PFKP Protein (AA 2-780) (His tag)

Produktnummer ABIN1945445

Produktdetails

Target: PFKP (phosphofructokinase, Platelet (PFKP))

Protein-Typ: Recombinant

Proteineigenschaft: AA 2-780

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses PFKP Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Phosphofructokinase 1/PFKM/PFKX (C-6His)

Sequenz: THEEHHAAKT LGIGKAIAVL TSGGDAQGMN AAVRAVVRVG IFTGARVFFV HEGYQGLVDG GDHIKEATWE SVSMMLQLGG TVIGSARCKD FREREGRLRA AYNLVKRGIT NLCVIGGDGS LTGADTFRSE WSDLLSDLQK AGKITDEEAT KSSYLNIVGL VGSIDNDFCG TDMTIGTDSA LHRIMEIVDA ITTTAQSHQR TFVLEVMGRH CGYLALVTSL SCGADWVFIP ECPPDDDWEE HLCRRLSETR TRGSRLNIII VAEGAIDKNG KPITSEDIKN LVVKRLGYDT RVTVLGHVQR GGTPSAFDRI LGSRMGVEAV MALLEGTPDT PACVVSLSGN QAVRLPLMEC VQVTKDVTKA MDEKKFDEAL KLRGRSFMNN WEVYKLLAHV RPPVSKSGSH TVAVMNVGAP AAGMNAAVRS TVRIGLIQGN RVLVVHDGFE GLAKGQIEEA GWSYVGGWTG QGGSKLGTKR TLPKKSFEQI SANITKFNIQ GLVIIGGFEA YTGGLELMEG RKQFDELCIP FVVIPATVSN NVPGSDFSVG ADTALNTICT TCDRIKQSAA GTKRRVFIIE TMGGYCGYLA TMAGLAAGAD AAYIFEEPFT IRDLQANVEH LVQKMKTTVK RGLVLRNEKC NENYTTDFIF NLYSEEGKGI FDSRKNVLGH MQQGGSPTPF DRNFATKMGA KAMNWMSGKI KESYRNGRIF ANTPDSGCVL GMRKRALVFQ PVAELKDQTD FEHRIPKEQW WLKLRPILKI LAKYEIDLDT SDHAHLEHIT RKRSGEAAVV DHHHHHH

Produktmerkmale: Recombinant Human 6-phosphofructokinase, muscle type/Phosphofructo-1-kinase isozyme A/Phosphofructokinase 1/Phosphohexokinase is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (AA 2-780) of Human PFKM fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: PFKP (phosphofructokinase, Platelet (PFKP))

Andere Bezeichnung: Phosphofructokinase 1 (PFKP Produkte)

Synonyme: pfk Protein, pfk-c Protein, pfkf Protein, PFKP Protein, PFK-C Protein, PFKF Protein, 1200015H23Rik Protein, 9330125N24Rik Protein, PFKM Protein, phosphofructokinase, platelet Protein, phosphofructokinase, platelet S homeolog Protein, ATP-dependent 6-phosphofructokinase, platelet type Protein, pfkp Protein, PFKP Protein, pfkp.S Protein, LOC100549777 Protein, Pfkp Protein

Hintergrund: 6-phosphofructokinase, muscle type is a muscle-type isozyme that in humans is encoded by the PFKM gene. It belongs to the phosphofructokinase family and Two domains subfamily. PFKM functions as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. PFK1 converts fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP.

Molekulargewicht: 86.1 kDa

UniProt: P08237

Pathways: Warburg Effekt