phosphodiesterase 6D, CGMP-Specific, Rod, delta Proteine (PDE6D)

Acts as a GTP specific dissociation inhibitor (GDI). Zusätzlich bieten wir Ihnen phosphodiesterase 6D, CGMP-Specific, Rod, delta Antikörper (39) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte PDE6D PDE6D 363272  
PDE6D 5147 O43924
PDE6D 18582 O55057
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Top phosphodiesterase 6D, CGMP-Specific, Rod, delta Proteine auf antikoerper-online.de

Showing 8 out of 9 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Anmelden zum Anzeigen Verfügbar
$284.90
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$492.31
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Escherichia coli (E. coli) Human His tag   1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$4,000.00
Details
Human Unkonjugiert   1 mg Anmelden zum Anzeigen 6 Days
$5,440.29
Details

PDE6D Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D) Interaktionspartnern

Human phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D) Interaktionspartner

  1. PDE6delta binds selectively to the C-terminus of RPGR (zeige RPGR Proteine) and that this interaction is critical for RPGR's localization to cilia.

  2. Studies indicate that the binding of UNC119 (zeige UNC119 Proteine) and PDE6D, to the lipid-modified ciliary cargo and the specific release of the cargo in the cilia by the ciliary small G-protein (zeige RAC2 Proteine) Arl3 in a GTP (zeige AK3 Proteine)-dependent manner.

  3. Study identifies PDE6D as a novel Joubert syndrome gene and provides the first evidence of prenyl-binding-dependent trafficking in ciliopathies.

  4. RPGR is acting as a scaffold protein recruiting cargo-loaded PDE6D and Arl3 to release lipidated cargo into cilia.

  5. findings indicate that ARL13B (zeige ARL13B Proteine), INPP5E, PDE6D, and CEP164 form a distinct functional network that is involved in JBTS and NPHP but independent of the ones previously defined by NPHP and MKS (zeige MKS1 Proteine) proteins

  6. Data show that PDEdelta activity augments K/Hras signalling by enriching Ras at the plasma membrane.

Cow (Bovine) phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D) Interaktionspartner

  1. Results suggest that PrBP/delta exclusively interacts with the soluble fraction of PDE6.

  2. The modest levels of basal activity exhibited by PDE6 purified from bovine rod outer segments (ROS (zeige ROS1 Proteine)) indicate that the inhibitory gamma subunit of PDE6 may not be tightly bound to PDE6 catalytic sites.

Mouse (Murine) phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D) Interaktionspartner

  1. the affinity to PDE6delta and the release by Arl2 (zeige ARL2 Proteine)/3 in addition to a retention signal are the determinants for cargo sorting and enrichment at its destination.

  2. Knockout of Unc119 (zeige UNC119 Proteine) partially reversed the transport defect of GRK1 (zeige GRK1 Proteine) in cone photoreceptors caused by deletion of Pde6d.

  3. absence of PrBP/delta in retina impairs transport of prenylated proteins, particularly rhodopsin kinase (zeige GRK1 Proteine) 1 and cone PDE (zeige TWIST1 Proteine), to rod and cone outer segments

phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D) Protein Überblick

Protein Überblick

Acts as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude and does so by decreasing the nucleotide dissociation rate. Stabilizes Arl3-GTP by decreasing the nucleotide dissociation (By similarity).

Genbezeichner und Symbole assoziert mit PDE6D

  • phosphodiesterase 6D (Pde6d)
  • phosphodiesterase 6D (PDE6D)
  • phosphodiesterase 6D, cGMP-specific, rod, delta (pde6d)
  • phosphodiesterase 6D, cGMP-specific, rod, delta (Pde6d)
  • AI841218 Protein
  • PDE6D Protein
  • PDED Protein
  • PrBP/delta Protein
  • zgc:92605 Protein

Bezeichner auf Proteinebene für PDE6D

retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta , phosphodiesterase 6D, cGMP-specific, rod, delta , Retinal rod rhodopsin-sensitive cGMP 3,5-cyclic phosphodiesterase subunit delta , phosphodiesterase 6D , GMP-PDE delta , protein p17 , cGMP-phosphodiesterase delta subunit , pde6D gene for cGMP-phosphodiesterase delta subunit

GENE ID SPEZIES
363272 Rattus norvegicus
424932 Gallus gallus
436981 Danio rerio
738319 Pan troglodytes
100286589 Salmo salar
100344476 Oryctolagus cuniculus
5147 Homo sapiens
281976 Bos taurus
403781 Canis lupus familiaris
18582 Mus musculus
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