anti-phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D) Antikörper

Acts as a GTP specific dissociation inhibitor (GDI). Zusätzlich bieten wir Ihnen phosphodiesterase 6D, CGMP-Specific, Rod, delta Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PDE6D 363272  
PDE6D 5147 O43924
PDE6D 18582 O55057
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Top anti-phosphodiesterase 6D, CGMP-Specific, Rod, delta Antikörper auf antikoerper-online.de

Showing 10 out of 36 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB ICC/IF Image Immunofluorescence analysis of methanol-fixed HeLa, using PDE6D, antibody at 1:500 dilution. WB Image Sample (30 ug of whole cell lysate) A: MOLT4 , 12% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 3 bis 4 Tage
$466.18
Details
Human Kaninchen Unkonjugiert WB PDE6D Antibody (Center)  western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the PDE6D antibody detected the PDE6D protein (arrow). PDE6D Antibody (Center)  western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the PDE6D antibody detected the PDE6D protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$385.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis in A2058 cell line lysates (35ug/lane). Western blot analysis in mouse heart tissue lysates (35ug/lane). 400 μL Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
Details
Human Maus Unkonjugiert IF, ELISA, WB PDE6D monoclonal antibody (M06), clone 5C7 Western Blot analysis of PDE6D expression in HeLa . Immunofluorescence of monoclonal antibody to PDE6D on HeLa cell. [antibody concentration 20 ug/ml] 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cell lines, using PDE6D antibody. 200 μL Anmelden zum Anzeigen 12 bis 14 Tage
$438.90
Details
Human Kaninchen Unkonjugiert ICC, IHC, IHC (p), WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
$537.17
Details
Maus Kaninchen Unkonjugiert ICC, IF, IHC, IHC (fro), WB   100 μg Anmelden zum Anzeigen 11 bis 14 Tage
$639.83
Details
Human Kaninchen Unkonjugiert ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 16 Tage
$658.43
Details
Human Kaninchen Unkonjugiert IF/ICC, IHC (fp), WB   100 μL Anmelden zum Anzeigen 6 bis 8 Tage
$431.20
Details

Am meisten referenzierte anti-phosphodiesterase 6D, CGMP-Specific, Rod, delta Antikörper

  1. Human Polyclonal PDE6D Primary Antibody für IHC, IHC (p) - ABIN4344439 : Thomas, Wright, Le Corre, Micalizzi, Romani, Abhyankar, Saada, Perrault, Amiel, Litzler, Filhol, Elkhartoufi, Kwong, Casanova, Boddaert, Baehr, Lyonnet, Munnich, Burglen, Chassaing, Encha-Ravazi et al.: A homozygous PDE6D mutation in Joubert syndrome impairs targeting of farnesylated INPP5E protein to the primary cilium. ... in Human mutation 2014 (PubMed)

Weitere Antikörper gegen phosphodiesterase 6D, CGMP-Specific, Rod, delta Interaktionspartner

Human phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D) Interaktionspartner

  1. PDE6delta binds selectively to the C-terminus of RPGR and that this interaction is critical for RPGR's localization to cilia.

  2. Studies indicate that the binding of UNC119 and PDE6D, to the lipid-modified ciliary cargo and the specific release of the cargo in the cilia by the ciliary small G-protein Arl3 in a GTP-dependent manner.

  3. Study identifies PDE6D as a novel Joubert syndrome gene and provides the first evidence of prenyl-binding-dependent trafficking in ciliopathies.

  4. RPGR is acting as a scaffold protein recruiting cargo-loaded PDE6D and Arl3 to release lipidated cargo into cilia.

  5. findings indicate that ARL13B, INPP5E, PDE6D, and CEP164 form a distinct functional network that is involved in JBTS and NPHP but independent of the ones previously defined by NPHP and MKS proteins

  6. Data show that PDEdelta activity augments K/Hras signalling by enriching Ras at the plasma membrane.

Cow (Bovine) phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D) Interaktionspartner

  1. Results suggest that PrBP/delta exclusively interacts with the soluble fraction of PDE6.

  2. The modest levels of basal activity exhibited by PDE6 purified from bovine rod outer segments (ROS) indicate that the inhibitory gamma subunit of PDE6 may not be tightly bound to PDE6 catalytic sites.

  3. PDEdelta functions as a prenyl-binding protein interacting with multiple prenylated proteins in retinal rods.

Mouse (Murine) phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D) Interaktionspartner

  1. It postulates a three-step mechanism regulating ciliary localization of INPP5E, consisting of farnesylation- and PDE6delta-mediated targeting, INPP5E-PDE6delta complex diffusion into the cilium with transfer to the IFT system, and retention inside cilia.

  2. the affinity to PDE6delta and the release by Arl2/3 in addition to a retention signal are the determinants for cargo sorting and enrichment at its destination.

  3. Knockout of Unc119 partially reversed the transport defect of GRK1 in cone photoreceptors caused by deletion of Pde6d.

  4. absence of PrBP/delta in retina impairs transport of prenylated proteins, particularly rhodopsin kinase 1 and cone PDE, to rod and cone outer segments

phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D) Antigen-Profil

Protein Überblick

Acts as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude and does so by decreasing the nucleotide dissociation rate. Stabilizes Arl3-GTP by decreasing the nucleotide dissociation (By similarity).

Genbezeichner und Symbole assoziert mit PDE6D

  • phosphodiesterase 6D (Pde6d) Antikörper
  • phosphodiesterase 6D (PDE6D) Antikörper
  • phosphodiesterase 6D, cGMP-specific, rod, delta (pde6d) Antikörper
  • phosphodiesterase 6D, cGMP-specific, rod, delta (Pde6d) Antikörper
  • AI841218 Antikörper
  • PDE6D Antikörper
  • PDED Antikörper
  • PrBP/delta Antikörper
  • zgc:92605 Antikörper

Bezeichner auf Proteinebene für PDE6D

retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta , phosphodiesterase 6D, cGMP-specific, rod, delta , Retinal rod rhodopsin-sensitive cGMP 3,5-cyclic phosphodiesterase subunit delta , phosphodiesterase 6D , GMP-PDE delta , protein p17 , cGMP-phosphodiesterase delta subunit , pde6D gene for cGMP-phosphodiesterase delta subunit

GENE ID SPEZIES
363272 Rattus norvegicus
424932 Gallus gallus
436981 Danio rerio
738319 Pan troglodytes
100286589 Salmo salar
100344476 Oryctolagus cuniculus
5147 Homo sapiens
281976 Bos taurus
403781 Canis lupus familiaris
18582 Mus musculus
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