gamma-Interferon-Induced Monokine (CXCL9) ELISA Kits

Human gamma-Interferon-Induced Monokine (CXCL9) Interaktionspartner

1. Study in human cervical epithelial cells and mouse model highlights Herpes simplex virus type 2 (HSV-2) ICP4 as a vital viral protein in promoting CXCR3 ligand expression and CXCL9 as the key induced chemokine in mediating CD4+ T cell migration in HSV-2 infection.

2. Serum MIG levels reflect Crohn disease activity, and it could be a marker for the responsiveness of patients to treatments

3. In primary biliary cirrhosis (PBC), circulating MIG levels and CXCR3+ cells are related with the progression of the disease; their expression increases significantly in PBC patients with respect to controls

4. Elevated Bronchoalveolar Lavage Fluid CXCL9 concentrations markedly increased the Risk of Chronic Lung Allograft Dysfunction.

5. The SNPs of CXCL9 (rs10336) and CXCL10 (rs3921) are not associated with the incidence of acute cellular rejection

6. IL1B promotes the transendothelial migration of mesenchymal stem cells through CXCR3-CXCL9 axis.

7. A causative role of myeloid Shp2 in dampening T cell-mediated antitumor immunity by restraining the macrophage/CXCL9-T cell/IFN-gamma feedback loop.

8. CXC chemokine ligand 9 promotes the progression of diffuse large B-cell lymphoma in a beta-catenin-dependent manner.

9. CXCL9 level was significantly higher in alopecia areata patients compared with controls and with vitiligo patients

10. CXCL9 may promote prostate cancer progression via inhibition of cytokines from T cells.

11. High CXCL9 expression is associated with invasion and metastasis in tongue squamous cell carcinoma.

12. MIG low in the tumor microenvironment can be used as potential indicators for the progression of non-small cell lung cancer

13. the results of the current study revealed increased serum levels of MIG as a novel independent marker of poor prognosis in newly diagnosed patients with MM.

14. High CXCL9 expression is associated with clear-cell renal cell carcinoma.

15. Circulating CXCL9 serum levels are high in chronic Q fever patients and is a promising biomarker for the diagnosis of chronic Q fever.

16. High urine CXCL9 level is associated with acute rejection in Histologically Stable Kidney transplant Recipients.

17. IL-27 stimulation activated STAT1 and STAT3 in HeLa and T98G cells, suggesting that IL-27 engages the STAT1/3 pathway, which then leads to the upregulation of IL-6, IP-10, and MIG

18. CXCL9 expression in lesional macrophages implicates the skin as the source of circulating cytokines. CXCL9 is a promising biomarker of disease activity in morphea.

19. results support the notion that CXCL9 and CXCL10 exert tumour-suppressive function by TIL recruitment in human ovarian cancer

20. significant correlation between serum levels and the severity of coronary artery disease, quantified by the Gensini score

Pig (Porcine) gamma-Interferon-Induced Monokine (CXCL9) Interaktionspartner

1. This report describes the cloning and characterization of expressed gene sequences of bovine, equine, and swine CXCL9 from RNA obtained from peripheral blood mononuclear cells and other tissues.

Cow (Bovine) gamma-Interferon-Induced Monokine (CXCL9) Interaktionspartner

1. CXCK9 and CXCL10 chemokines displayed a trend of decreasing mRNA expression as lesion progressed, suggesting a higher level of importance during the early stages of the immune response to mycobacterial infection.

2. This report describes the cloning and characterization of expressed gene sequences of bovine, equine, and swine CXCL9 from RNA obtained from peripheral blood mononuclear cells and other tissues.

Mouse (Murine) gamma-Interferon-Induced Monokine (CXCL9) Interaktionspartner

1. Study in human cervical epithelial cells and mouse model highlights Herpes simplex virus type 2 (HSV-2) ICP4 as a vital viral protein in promoting CXCR3 ligand expression and CXCL9 as the key induced chemokine in mediating CD4+ T cell migration in HSV-2 infection.

2. Study show that CXCL9 and CXCL10 are overexpressed in skin of HPV16 E7 transgenic mice when compared with non-transgenic animals. Immune cell infiltration to E7 transgenic skin is a consequence of epidermal hyperplasia, and that hyperplasia induces CXCL9 and CXCL10 production to recruit a subset of CXCR3+ T cells, promoting rejection of grafted E7 transgenic skin depleted of immunosuppressive lymphocytes.

3. These findings demonstrate that CD11b(+) B cells induced in PPs during colitis actively recruit Treg cells to accomplish IgA isotype switch in a CXCL9-dependent manner.

4. although the expression of CXCL9 and CXCL11 are increased after spinal nerve ligation, they may not contribute to the maintenance of neuropathic pain.

5. CXCL9 may promote prostate cancer progression via inhibition of cytokines from T cells.

6. Cxcl9 has a role in angiogenesis and osteogenesis in bone.

7. Advanced glycation end products induce apoptosis and inflammation in mouse podocytes through CXCL9-mediated JAK2/STAT3 pathway activation.

8. Data suggest that the CXCL9-CXCR3 axis plays a pivotal role in the liver-specific distribution of TRAIL+ NK cells in mice.

9. IFNalphaR1 signaling promoted CXCL9 and CXCL10 synthesis, suggesting that these chemokines might be involved in the LPS and CD134 costimulation response.

10. CXCL10 plays in the pathogenesis of recurrent Herpetic stromal keratitis, and that CXCL9 displays its importance when CXCL10 is absent.

11. CXCL9 expression is strongly upregulated in PGRN KO mice and its level is correlated with severity of inflammation in a dermatitis model.

12. hepatic expression of the inflammatory CXC chemokine ligands (CXCL)9 and CXCL10 strongly increased whereas homeostatic CXCL12 significantly decreased.

13. Here, we report the evidence for the production of MIG, a second CXCR3 ligand, during the primary immune response to HSV-1 corneal infection.

14. These findings identify a novel role for the immune cell-derived CXCL9 chemokine in directing a protective antimicrobial response in the intestinal mucosa.

15. These results indicate that CXCL9 is crucial for recruiting immune T cells into the brain and inducing an accumulation of the T cells into the areas where tachyzoites proliferate to prevent reactivation of chronic T. gondii infection.

16. tumours are characterized by expression of inflammatory chemokines (CCL2, CCL5, CCL7, CCL8, CCL12, CXCL9, CXCL10 and CX3CL1), reflected by an enrichment of activated Foxp3(-) and Foxp3(+) T cells

17. Data show that testosterone treatment of female mice significantly reduced the expression of interleukin 17A (IL-17A), chemokines CXCL-9 and CXCL-10 within the liver.

18. Aged mice had similar levels of IL-1beta, TNF, IFN-gamma, IL-17, and granulocyte colony-stimulating factor following S. pneumoniae infection, compared with young mice, but increased levels of the chemokines CXCL9, CXCL12, CCL3, CCL4, CCL5, CCL11, and CCL17.

19. These findings functionally integrate K17, hnRNP K, and gene expression along with RSK and CXCR3 signaling in a keratinocyte-autonomous axis and provide a potential basis for their implication in tumorigenesis

20. In our mouse model, fatal progression of AIH is mediated by IL-18-dependent differentiation of T cells into Th1 cells and effector T cells, respectively, and that CXCR3-CXCL9 axis-dependent migration of those T cells is crucial for fatal progression.