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ZNRF1 encodes an E3 ubiquitin-protein ligase that plays a role in neural-cell differentiation.
Showing 6 out of 7 products:
rs17684886 (ZNRF1) and rs599019 (COLEC12 (zeige COLEC12 Proteine)) are associated with diabetic retinopathy and rs6427247 (SCYL1BP1 (zeige GORAB Proteine)) and rs899036 (API5 (zeige API5 Proteine)) are associated with severe diabetic retinopathy in Chinese patients with type 2 diabetes
ZNRF1 and ZNRF2 (zeige ZNRF2 Proteine) are new players in regulation of the ubiquitous Na(+)/K(+)ATPase (zeige ATP1A1 Proteine) that is tuned to changing demands in many physiological contexts.
data suggest that ZNRF proteins play a role in the establishment and maintenance of neuronal transmission and plasticity via their ubiquitin ligase activity
These results suggest that ZNRF1 mediates regulation of neuritogenesis via interaction with tubulin (zeige TUBB Proteine).
up-regulation of ZNRF1 activity by oxidative stress leads to neuronal apoptosis and Wallerian degeneration.
The ZNRF1-AKT (zeige AKT1 Proteine)-GSK3B-CRMP2 (zeige DPYSL2 Proteine) pathway plays an important role in controlling Wallerian degeneration.
This gene encodes an E3 ubiquitin-protein ligase that plays a role in neural-cell differentiation. Overexpression of this gene causes neurite-like elongation. The encoded protein contains both a zinc finger and a RING finger motif and is localized in the endosome/lysosome compartment, indicating that it may be involved in ubiquitin-mediated protein modification, and in synaptic vessicle membranes in neurons.
E3 ubiquitin-protein ligase ZNRF1
, nerve injury gene 283
, nerve injury-induced gene 283 protein
, zinc and ring finger protein 1
, zinc/RING finger protein 1
, peripheral nerve injury protein nin283
, ring finger protein 42
, zinc ring finger protein 1
, E3 ubiquitin-protein ligase ZNRF2
, zinc and ring finger 1
, E3 ubiquitin-protein ligase znrf1