Zinc Finger Protein 36, C3H Type, Homolog (Mouse) Proteine (ZFP36)

mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Zusätzlich bieten wir Ihnen ZFP36 Antikörper (98) und ZFP36 Kits (11) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
ZFP36 7538 P26651
Maus ZFP36 ZFP36 22695 P22893
Ratte ZFP36 ZFP36 79426 P47973
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Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,871.00
Details

ZFP36 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,

Am meisten referenzierte ZFP36 Proteine

  1. Human ZFP36 Protein expressed in Wheat germ - ABIN1325745 : McDermott, Ellis, Bou-Gharios, Clegg, Tew: RNA binding proteins regulate anabolic and catabolic gene expression in chondrocytes. in Osteoarthritis and cartilage 2016 (PubMed)

Weitere Proteine zu Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) Interaktionspartnern

Human Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) Interaktionspartner

  1. The role of TTP (zeige ADAMTS13 Proteine) in human cancers and immunity.[review]

  2. Findings reveal tristetraprolin, which is known to bind COX-2 mRNA and promote its rapid degradation, as regulator of COX-2 expression in influenza A viruses (IAV) infection. During IAV replication and viral RNA accumulation TTP (zeige ADAMTS13 Proteine) mRNA synthesis was induced, resulting in reduced COX-2 levels.

  3. our data demonstrate that TTP (zeige ADAMTS13 Proteine) acts as a regulator of mitochondrial dynamics through enhancing degradation of alpha-Syn mRNA in cancer cells. This finding will increase understanding of the molecular basis of mitochondrial dynamics.

  4. Suggest that TTP (zeige ADAMTS13 Proteine) is an important prognostic indicator for prostate cancer, and augmenting TTP (zeige ADAMTS13 Proteine) function would effectively disable the metabolism and proliferation of aggressive prostate tumors.

  5. RAS signaling can upregulate tumor cell PD-L1 (zeige CD274 Proteine) expression through a mechanism involving increases in PD-L1 (zeige CD274 Proteine) mRNA stability via modulation of the AU-rich element-binding protein tristetraprolin.

  6. Because TTP (zeige ADAMTS13 Proteine) also represses IL-1beta (zeige IL1B Proteine) expression, it is a dual inhibitor of the IL-1beta (zeige IL1B Proteine) system, regulating expression of the cytokine and the upstream controller NLRP3 (zeige NLRP3 Proteine)

  7. Data show that the synthetic liver X receptors (LXRs) agonist T0901317 promoted cytokines IL-1beta (zeige IL1B Proteine), IL-6 (zeige IL6 Proteine) and TNFalpha (zeige TNF Proteine) mRNA degradation, destabilized TNFalpha (zeige TNF Proteine) mRNA through its 3'-untranslated region, and increased the expression of tristetraprolin (TTP).

  8. TTP (zeige ADAMTS13 Proteine) was demonstrated to destabilize the VEGF (zeige VEGFA Proteine) mRNA in ARPE-19 cells under hypoxic conditions. Furthermore, CM from TTP (zeige ADAMTS13 Proteine)-overexpressing ARPE-19 cells suppressed tube formation in HUVECs.

  9. this study shows that TTP (zeige ADAMTS13 Proteine) is down-regulated in glioma tissue samples and cell lines, and is associated with diminished survival in glioma patients

  10. TTP (zeige ADAMTS13 Proteine) inhibited the proliferation, migration, and invasion of gastric cancer cell lines through regulation of IL-33 (zeige IL33 Proteine).

Pig (Porcine) Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) Interaktionspartner

  1. direct interaction between TTP protein and porcine TNF-alpha (zeige TNF Proteine) mRNA ARE probe

Mouse (Murine) Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) Interaktionspartner

  1. mRNA-binding protein tristetraprolin (TTP) is induced by iron deficiency and degrades mRNAs of mitochondrial Fe/S-cluster-containing proteins, specifically Ndufs1 (zeige NDUFS1 Proteine) in complex I and Uqcrfs1 (zeige UQCRFS1 Proteine) in complex III, to match the decrease in Fe/S-cluster availability.

  2. Expression of the RNA-binding protein, tristetraprolin (TTP) was down-regulated in response to calcineurin inhibition.

  3. by utilizing Ttp-/- mice we demonstrated the in vivo anti-inflammatory role of Ttp in radiation pneumonitis.

  4. Results suggest that RNA-binding proteins such as TTP are expressed and perhaps involved in the modulation of inflammation-induced pregnancy pathologies.

  5. The authors found that the endogenous Zfp36 directly interacts with the cytoplasmic poly(A)-binding protein. Importantly, this interaction is required for the translational repression of Zfp36's target mRNAs in resolving inflammation.

  6. degrades p28 (zeige GSTO1 Proteine) to inhibit IL-27 (zeige IL27 Proteine) production by macrophages and is thereby a negative regulator of the antitumour response

  7. Results suggest that tristetraprolin (TTP) as a cytoskeletal regulator is required for spindle morphology/chromosome alignment and actin polymerization in oocytes.

  8. RAS signaling can upregulate tumor cell PD-L1 (zeige CD274 Proteine) expression through a mechanism involving increases in PD-L1 (zeige CD274 Proteine) mRNA stability via modulation of the AU-rich element-binding protein tristetraprolin.

  9. these data support the hypothesis that TTP plays a role in the post-transcriptional regulation of the ODC (zeige ODC1 Proteine) mRNA transcript.

  10. Posttranscriptional gene regulation by TTP schedules the termination of the antimicrobial engagement of neutrophils.

ZFP36 Protein Überblick

Protein Überblick

mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF).

Genbezeichner und Symbole assoziert mit ZFP36

  • ZFP36 ring finger protein (ZFP36)
  • ZFP36 ring finger protein L homeolog (zfp36.L)
  • tristetraproline (EDI_287240)
  • Tristetraproline (Bm1_42085)
  • tristetraproline (LOAG_03119)
  • similar to Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth (ZFP36)
  • ZFP36 ring finger protein (zfp36)
  • zinc finger protein 36 (Zfp36)
  • ZFP36 ring finger protein (Zfp36)
  • C3H-1 Protein
  • g0s24 Protein
  • Gos24 Protein
  • Nup475 Protein
  • rnf162a Protein
  • Tis11 Protein
  • TIS11D Protein
  • TISII Protein
  • Ttp Protein
  • Zfp-36 Protein
  • ZFP36 Protein

Bezeichner auf Proteinebene für ZFP36

G0/G1 switch regulatory protein 24 , growth factor-inducible nuclear protein NUP475 , tristetraprolin , tristetraproline , zinc finger protein 36 homolog , zinc finger protein 36, C3H type, homolog , zinc finger protein, C3H type, 36 homolog , CCCH zinc finger protein C3H-1 , Tristetraproline , TIS11 , TTP , zfp-36 , zinc finger protein homologous to Zfp-36 in mouse , similar to Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth , zinc finger protein 36, C3H type, homolog (mouse) , CCCH (CX8CX5CX3H) zinc finger domain RNA-binding protein , TPA-induced sequence 11 , TNF alpha inhibitor , Tax interacting protein

GENE ID SPEZIES
7538 Homo sapiens
398102 Xenopus laevis
5879635 Entamoeba dispar SAW760
6103302 Brugia malayi
9940506 Loa loa
282127 Bos taurus
698280 Macaca mulatta
736203 Pan troglodytes
100127733 Xenopus (Silurana) tropicalis
100316849 Sus scrofa
22695 Mus musculus
79426 Rattus norvegicus
484510 Canis lupus familiaris
443283 Ovis aries
100733110 Cavia porcellus
100340391 Oryctolagus cuniculus
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