Zinc Finger Protein 278 Proteine (ZNF278)

The protein encoded by ZNF278 contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Zusätzlich bieten wir Ihnen Zinc Finger Protein 278 Antikörper (20) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
ZNF278 23598 Q9HBE1
Maus ZNF278 ZNF278 56218  
Ratte ZNF278 ZNF278 305471  
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Top Zinc Finger Protein 278 Proteine auf antikoerper-online.de

Showing 3 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$8,498.50
Details
Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$338.33
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Anmelden zum Anzeigen 10 bis 12 Tage
$251.74
Details

ZNF278 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
,

Weitere Proteine zu Zinc Finger Protein 278 (ZNF278) Interaktionspartnern

Human Zinc Finger Protein 278 (ZNF278) Interaktionspartner

  1. this study show that PATZ1 expression correlates positively with BAX (zeige BAX Proteine) and negatively with BCL6 (zeige BCL6 Proteine) and survival in human diffuse large B cell lymphomas

  2. Our results suggest that PATZ1 and PP4R2 (zeige PPP4R2 Proteine) provide negative feedback on IKK (zeige CHUK Proteine)/NF-kappaB (zeige NFKB1 Proteine) signaling to prevent cancer cells from over-stimulation from cellular stimuli

  3. The derived allele of rs174557, which is the common variant in most populations, diminishes binding of PATZ1, a transcription factor conferring allele-specific downregulation of FADS1 (zeige FADS1 Proteine).

  4. Loss of PATZ1 expression is associated with thyroid cancer progression.

  5. Results show that PATZ1 binds to p53 (zeige TP53 Proteine) and inhibits p53 (zeige TP53 Proteine)-dependent transcription activation.

  6. these results propose that Patz1 is important for ESC pluripotency.

  7. The data support a PATZ1 tumour-suppressive function based on its ability to enhance p53 (zeige TP53 Proteine)-dependent transcription and apoptosis.

  8. PATZ1 may have an important role in the regulation of EC senescence through an ROS (zeige ROS1 Proteine)-mediated p53 (zeige TP53 Proteine)-dependent pathway and contribute to vascular diseases associated with aging.

  9. these results showed a potentially novel mechanism of cAMP signaling mediated through the interaction of RIalpha (zeige PRKAR1A Proteine) with PATZ1.

  10. MAZR and MITF (zeige MITF Proteine) synergistically transactivated the mMCP-6 gene. MAZR appeared to play important roles in the normal phenotypic expression of mast cells in association with MITF (zeige MITF Proteine)

Mouse (Murine) Zinc Finger Protein 278 (ZNF278) Interaktionspartner

  1. endothelial PATZ1 thus potently inhibits endothelial function and angiogenesis via inhibition of FABP4 (zeige FABP4 Proteine) expression, and abnormal induction of endothelial PATZ1 may contribute to multiple aspects of vascular dysfunction in diabetes

  2. Together, these results suggest a novel mechanism regulating endothelial PATZ1 expression based on the down-regulation of miR (zeige MLXIP Proteine)-24 expression caused by hyperglycemia. Interfering with PATZ1 expression via miRNAs or miRNA mimics could potentially represent a new way to target endothelial PATZ1-dependent signaling of vascular dysfunction in diabetes.

  3. the repression of ThPOK (zeige ZBTB7B Proteine) during CD8 (zeige CD8A Proteine) lineage differentiation is mediated by the synergistic activity of the transcription factor MAZR and Runx/CBFbeta (zeige CBFB Proteine) complexes.

  4. Results show that PATZ1 binds to p53 (zeige TP53 Proteine) and inhibits p53 (zeige TP53 Proteine)-dependent transcription activation.

  5. The data support a PATZ1 tumour-suppressive function based on its ability to enhance p53 (zeige TP53 Proteine)-dependent transcription and apoptosis.

  6. analysis of embryos in which Patz1 was disrupted revealed the presence of severe defects in the CNS and in the cardiac outflow tract, which eventually lead to a pre-mature in utero death during late gestation or soon after birth

  7. PATZ1 may have an important role in the regulation of EC senescence through an ROS (zeige ROS1 Proteine)-mediated p53 (zeige TP53 Proteine)-dependent pathway and contribute to vascular diseases associated with aging.

  8. controls the CD4 (zeige CD4 Proteine) versus CD8 (zeige CD8A Proteine) lineage fate of double-positive thymocytes

  9. MAZR and MITF (zeige MITF Proteine) synergistically transactivated the mMCP-6 gene. MAZR appeared to play important roles in the normal phenotypic expression of mast cells in association with MITF (zeige MITF Proteine)

  10. results demonstrate epigenetic control of the Cd8 (zeige CD8A Proteine) loci and identify MAZR as an important regulator of Cd8 (zeige CD8A Proteine) expression

Zinc Finger Protein 278 (ZNF278) Protein Überblick

Protein Überblick

The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated t1\;22p36.1\;q12. The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene.

Genbezeichner und Symbole assoziert mit ZNF278

  • POZ/BTB and AT hook containing zinc finger 1 (PATZ1)
  • POZ/BTB and AT hook containing zinc finger 1 S homeolog (patz1.S)
  • POZ (BTB) and AT hook containing zinc finger 1 (Patz1)
  • POZ-, AT hook-, and zinc finger-containing protein 1 (LOC100153931)
  • 8430401L15Rik Protein
  • AI447519 Protein
  • dJ400N23 Protein
  • Mazr Protein
  • Patz Protein
  • RIAZ Protein
  • ZBTB19 Protein
  • Zfp278 Protein
  • Znf278 Protein
  • ZSG Protein

Bezeichner auf Proteinebene für ZNF278

zinc finger protein 278 , BTB-POZ domain zinc finger transcription factor , BTB/POZ domain zinc finger transcription factor , MAZ-related factor , POZ-, AT hook-, and zinc finger-containing protein 1 , POZ-AT hook-zinc finger protein , protein kinase A RI subunit alpha-associated protein , zinc finger and BTB domain-containing protein 19 , zinc finger sarcoma gene protein , POZ and AT hook containing zinc finger 1 long C isoform , transcription factor (MAZ-related) MAZR

GENE ID SPEZIES
100058375 Equus caballus
733194 Xenopus laevis
416963 Gallus gallus
23598 Homo sapiens
486365 Canis lupus familiaris
100328729 Oryctolagus cuniculus
56218 Mus musculus
305471 Rattus norvegicus
532416 Bos taurus
100153931 Sus scrofa
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