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Transcriptional activator. Zusätzlich bieten wir Ihnen Zinc Finger Protein 143 Antikörper (25) und und viele weitere Produktgruppen zu diesem Protein an.
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The inhibition of ZNF143 activity by small molecules induced tumor regression.
Data show that zinc finger protein 143 (ZNF143) promotes epithelial-mesenchymal transition (EMT (zeige ITK Proteine)) through regulating PI3K (zeige PIK3CA Proteine)/AKT (zeige AKT1 Proteine) pathway in gastric cancer (GC) cells.
The results show that as an important partner of CTCF, ZNF143 helps establishing the conserved chromatin structure by cooperating with cohesin.
ZNF143 is directly recruited to the promoter of genes engage in chromatin interactions, where it binds to its DNA recognition sequence.
THAP11, ZNF143, and HCF-1 (zeige HCFC1 Proteine) form a mutually dependent complex on chromatin, which is independent of E2F (zeige E2F1 Proteine) occupancy.
ZNF143 expresses different 3'-untranslated regions (3'-UTR) as a result of alternative polyadenylation
High zinc-finger protein 143 is associated with cancer cell migration and invasion through ZEB1 and E-cadherin (zeige CDH1 Proteine) in colon cancer.
HCFC1 (zeige HCFC1 Proteine) is a common component of active human CpG-island promoters and coincides with ZNF143, THAP11, YY1 (zeige YY1 Proteine), and GABP transcription factor occupancy.
ZNF143 upregulated GPX1 (zeige GPX1 Proteine) activity and protecting cells from oxidative damage.
GIPC (zeige GIPC1 Proteine) is involved in IGF-1 (zeige IGF1 Proteine) signaling leading to ZNF143 expression through the regulation of ROS (zeige ROS1 Proteine) production, which may play a role for colon cancer tumorigenesis.
Zfp143 regulates Nanog (zeige NANOG Proteine) expression through modulation of Oct4 (zeige POU5F1 Proteine) binding.
STAF influences selenoprotein expression by enhancing Sec tRNA gene synthesis in an organ-specific manner
The knockdown of the transcriptional activator ZNF143 by injection of translational-blocking Morpholino Oligonucleotides causes many significant phenotypic effects in zebrafish embryos
Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8 (By similarity).
, selenocysteine tRNA gene transcription-activating factor
, transcriptional activator Staf
, selenocysteine tRNA gene transcription activating factor
, zinc finger protein 80, related sequence 1
, Selenocysteine tRNA gene transcription-activating factor
, selenocysteine tRNA activating factor
, zinc finger protein 143