Zinc Finger Protein, X-Linked Proteine (ZFX)

ZFX on the X chromosome is structurally similar to a related gene on the Y chromosome. Zusätzlich bieten wir Ihnen ZFX Antikörper (47) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Maus ZFX ZFX 22764 P17012
Ratte ZFX ZFX 367832  
ZFX 7543 P17010
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
Hefe Wildschwein His tag   1 mg 60 bis 71 Tage

ZFX Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat

Weitere Proteine zu Zinc Finger Protein, X-Linked (ZFX) Interaktionspartnern

Mouse (Murine) Zinc Finger Protein, X-Linked (ZFX) Interaktionspartner

  1. our findings show that RNAi-mediated disruption of Zfx/Zfy in mouse testis affected X/Y spermatogenesis. Additionally, results suggest that the paralogous genes Zfx/Zfy play an important role in the process of X and Y sperm development. The individual interference of Zfx/Zfy may predict the outcome of X and Y haploid sperms. Presented herein is an advanced method developed to control mouse X/Y spermatogenesis and sex rati

  2. Zfx is a common cell-intrinsic regulator of diverse Hedgehog-induced tumors.

  3. Zfx, a transcription factor that controls hematopoietic stem cell self-renewal, controls the initiation and maintenance of acute myeloid leukemia.

  4. These studies identify Zfx as a shared transcriptional regulator of embryonic stem cells and hematopoietic stem cells, suggesting a common genetic basis of self-renewal in embryonic and adult SC.

  5. Zfx restrains the stress response and couples antigen receptor signaling to cell expansion and maintenance during B-cell development and peripheral homeostasis

Human Zinc Finger Protein, X-Linked (ZFX) Interaktionspartner

  1. AR-V7 has both ARE/FOXA1 canonical and ZFX-directed non-canonical regulatory functions in the evolution of anti-androgen therapeutic resistance.

  2. ZFX-spliced transcripts could be considered as novel tumor markers with a probable value in diagnosis, prognosis, and therapy of breast cancer.

  3. MiR-493 functioned as tumor suppressor in HCC cells by regulating ZFX expression. Thus, miR-493 may provide potential value for HCC treatment.

  4. The depletion of ZFX using lentiviral shRNAs significantly inhibited cell proliferation by inducing cell cycle arrest in G0/G1 phase and resulted in increased cell apoptosis and invasive repression.

  5. The research findings indicate that Zinc finger protein X-linked (ZFX) activates and maintains EpCAM(+) liver cancer stem cells by promoting nuclear translocation and transactivation of beta-catenin. Furthermore, combination of ZFX and epithelial cell adhesion molecule (EpCAM) may serve as a significant indicator for prognosis of patients with hepatocellular carcinoma.

  6. Findings indicate that zinc-finger protein X-linked (ZFX) promotes colorectal cancer (CRC) progression by suppressing dual specificity phosphatase 5 (DUSP5) expression and suggest that ZFX is a prognostic biomarker and potentially useful therapeutic target in stage II/III CRC patients.

  7. colon cancer-associated transcript-1 knockdown inhibits proliferation and invasion of laryngeal squamous cell cancer cells through enhancing zinc finger protein, X-linked by sponging microRNA-218, elucidating a novel colon cancer-associated transcript-1-microRNA-218-zinc finger protein, X-linked regulatory axis in laryngeal squamous cell cancer and providing a promising therapeutic target for laryngeal cancer

  8. EZH2 and ZFX genes do not seem to have an impact on the onset of most parathyroid tumours, both benign and malignant, though further studies on larger cohorts of different ethnicity are needed.

  9. Zinc finger and X-linked factor ZFX transactivates the SET transcript 2 promoter through binding to a site closely located to the transcription start site.

  10. miR-144 has been demonstrated to act as a tumour suppressor in hepatocellular carcinoma (HCC) cell growth and motility by directly targeting ZFX, which implicates its potential applications in the development of HCC treatment

  11. demonstrated that ZFX is aberrantly expressed in multiple human leukemic cells and it modulates the growth and drug response of leukemic cells partially via B4GALT1, which suggests that ZFX is a new regulator of leukemic cells and warrants intensive investigations on this 'stemness' regulator in these deadly diseases

  12. ZFX is a novel oncogene promoting cell proliferation and inducing imatinib resistance via PI3K/Akt signaling pathway

  13. Zinc finger protein x-linked contributes to patient prognosis, and regulates cell proliferation and apoptosis in human laryngeal squamous cell carcinoma.

  14. ZFX expression may have a role in poor prognosis of renal cell carcinoma patients

  15. Nasopharyngeal carcinoma patients with high ZFX expression had lower 5-year overall survival rates, progression-free survival rates, loco-regional relapse-free survival rates and distant metastasis-free survival rates than those with low ZFX expression

  16. Our results provide evidence suggesting that ZFX overexpression is associated with the development of tongue SCC and ZFX knockdown is a potential treatment for tumor suppression

  17. These data demonstrate that ZFX functions as a critical upstream regulator of c-Myc and plays essential roles in the maintenance of the glioma stem cells phenotype

  18. ZFX is essential for the development and progression of squamous cell carcinoma of the tongue.

  19. our findings for the first time demonstrated that ZFX expression may be associated with the progress of colorectal cancer

  20. Study detected the expression of ZFX in 42 patients with renal cancer and found the expression of ZFX was specifically upregulated in cancer tissues at the mRNA and protein levels.

Cow (Bovine) Zinc Finger Protein, X-Linked (ZFX) Interaktionspartner

  1. ZFX transcripts were noted in all pre-compaction stage embryos and in female and male blastocysts; the expression of ZFX was significantly higher in female than in male blastocysts

ZFX Protein Überblick

Protein Überblick

This gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined.

Genbezeichner und Symbole assoziert mit ZFX

  • zinc finger protein X-linked (Zfx)
  • zinc finger protein, X-linked S homeolog (zfx.S)
  • zinc finger protein, X-linked (ZFX)
  • RGD1562664 Protein
  • xzfy-1 Protein
  • Zfx5 Protein
  • Zfx5,6 Protein
  • Zfx6 Protein
  • zfy1 Protein
  • ZNF926 Protein

Bezeichner auf Proteinebene für ZFX

X-linked zinc finger protein , zinc finger X-chromosomal protein , zinc finger protein X-linked 5 , zinc finger protein X-linked 6 , ZFY-1 , zinc finger Y-chromosomal protein 1 , zinc finger protein 1, Y linked , zinc finger protein X-linked , Zinc finger X-chromosomal protein , zinc finger protein ZFX

22764 Mus musculus
367832 Rattus norvegicus
397971 Xenopus laevis
7543 Homo sapiens
280961 Bos taurus
397294 Sus scrofa
491778 Canis lupus familiaris
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