Zinc Finger CCCH-Type Containing 14 Proteine (ZC3H14)

ZC3H14 belongs to a family of poly(A)-binding proteins that influence gene expression by regulating mRNA stability, nuclear export, and translation (Kelly et al., 2007 [PubMed 17630287]).[supplied by OMIM, Mar 2010].. Zusätzlich bieten wir Ihnen ZC3H14 Antikörper (39) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Maus ZC3H14 ZC3H14 75553 Q8BJ05
ZC3H14 192359 Q7TMD5
ZC3H14 79882 Q6PJT7
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Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$4,150.67
Details

ZC3H14 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Rat (Rattus)

Human ,
,

Weitere Proteine zu Zinc Finger CCCH-Type Containing 14 (ZC3H14) Interaktionspartnern

Caenorhabditis elegans (C. elegans) Zinc Finger CCCH-Type Containing 14 (ZC3H14) Interaktionspartner

  1. Study identified sut-2 as a gene required for tau neurotoxicity in C. elegans and cloned the sut-2 gene and found it encodes a novel sub-type of CCCH zinc finger protein conserved across animal phyla.

Mouse (Murine) Zinc Finger CCCH-Type Containing 14 (ZC3H14) Interaktionspartner

  1. Among the proteins increased in the hippocampi of Zc3h14Deltaex13/Deltaex13 mice compared to control are key synaptic proteins including CaMK2a (zeige CAMK2A Proteine). This newly generated mouse serves as a tool to study the function of ZC3H14 in vivo.

Human Zinc Finger CCCH-Type Containing 14 (ZC3H14) Interaktionspartner

  1. ATP5G1 (zeige ATP5G1 Proteine) turnover increases upon depletion of ZC3H14, double knockdown of ZC3H14 and the nonsense-mediated decay factor, UPF1 (zeige UPF1 Proteine), rescues ATP5G1 (zeige ATP5G1 Proteine) transcript levels. Furthermore, fractionation reveals an increase in the amount of ATP5G1 (zeige ATP5G1 Proteine) pre-mRNA that reaches the cytoplasm when ZC3H14 is depleted and that ZC3H14 binds to ATP5G1 (zeige ATP5G1 Proteine) pre-mRNA in the nucleus.

  2. we show here that human ZC3H14 can functionally substitute for dNab2 in fly neurons and can rescue defects in development and locomotion that are present in dNab2 null flies

  3. report a intellectual disability disease locus on chromosome 14q31.3 corresponding to mutation of the ZC3H14 gene that encodes a conserved polyadenosine RNA binding protein

  4. MSUT2 levels may influence neuronal vulnerability to tau toxicity and aggregation.

  5. New neuroprotective strategies targeting MSUT-2 that may be effective in modulating tau neurotoxicity in human tauopathy disorders.

  6. multiple transcripts encoding several ZC3H14 isoforms exist in vivo

ZC3H14 Protein Überblick

Protein Überblick

ZC3H14 belongs to a family of poly(A)-binding proteins that influence gene expression by regulating mRNA stability, nuclear export, and translation (Kelly et al., 2007

Genbezeichner und Symbole assoziert mit ZC3H14

  • Zinc finger CCCH domain-containing protein 14 (sut-2)
  • zinc finger CCCH type containing 14 (Zc3h14)
  • zinc finger CCCH-type containing 14 (ZC3H14)
  • zinc finger CCCH-type containing 14 S homeolog (zc3h14.S)
  • 1010001P15Rik Protein
  • 1700016A15Rik Protein
  • 2700069A02RIK Protein
  • AU014748 Protein
  • MSUT-2 Protein
  • Npuk68 Protein
  • NY-REN-37 Protein
  • SUT2 Protein
  • UKp68 Protein

Bezeichner auf Proteinebene für ZC3H14

zinc finger CCCH domain-containing protein 14 , zinc finger CCCH-type containing 14 , nuclear protein UKp68 , nuclear protein UKp83/UKp68 , mammalian suppressor of tau pathology-2 , renal carcinoma antigen NY-REN-37

GENE ID SPEZIES
178847 Caenorhabditis elegans
75553 Mus musculus
192359 Rattus norvegicus
79882 Homo sapiens
480412 Canis lupus familiaris
511473 Bos taurus
423399 Gallus gallus
100158380 Xenopus laevis
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