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The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. Zusätzlich bieten wir Ihnen WBP2 Antikörper (40) und viele weitere Produktgruppen zu diesem Protein an.
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WBP2/ITCH signaling functions to link the intricate Wnt (zeige WNT2 Proteine) and Hippo signaling networks in breast cancer.
the miR (zeige MLXIP Proteine)-206/WBP2 axis can modulate tamoxifen sensitivity via regulating G1/S progression in estrogen receptor (zeige ESR1 Proteine) + breast cancer
The authors reported that the loss of Wbp2 expression leads to progressive high-frequency hearing loss in mouse, as well as in two deaf children, each carrying two different variants in the WBP2 gene.
data indicate that WBP-2 enhances ER transactivation function at certain genes by facilitating the recruitment and/or the stabilization of a histone modifier enzyme that favors a relaxed chromatin structure, permissive of transcription
The WW1 and WW2 domains of YAP2 (zeige YAP1 Proteine) recognize various PPXY motifs within WBP2 and WBP1 (zeige DDOST Proteine) in a highly promiscuous and subtle manner.
Data show that direct interaction of Wbp2 with TAZ (zeige TAZ Proteine) depends on the WW domain of TAZ (zeige TAZ Proteine).
WW domain binding protein-2, an E6-associated protein interacting protein, acts together with YAP (zeige YAP1 Proteine) as coactivators of estrogen and progesterone receptors.
This study established WBP2 as a tyrosine phosphorylation target of estrogen signaling via EGFR (zeige EGFR Proteine) crosstalk.
The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein, which binds to the WW domain of Yes kinase-associated protein by its PY motifs. The function of this protein has not been determined.
WW domain-binding protein 2
, WW domain binding protein 2
, WW domain binding protein 2-like