anti-WAP Four-Disulfide Core Domain 2 (WFDC2) Antikörper

WFDC2 encodes a protein that is a member of the WFDC domain family. Zusätzlich bieten wir Ihnen WFDC2 Proteine (27) und WFDC2 Kits (25) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
WFDC2 10406 Q14508
WFDC2 67701 Q9DAU7
WFDC2 286888 Q8CHN3
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Top anti-WFDC2 Antikörper auf antikoerper-online.de

Showing 10 out of 175 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Maus Kaninchen Unkonjugiert IHC (p), ELISA, WB IF analysis of human ovarian cancer tissue using HE4 antibody (dilution of primary antibody at 1:100) Immunohistochemical staining of paraffin embedded human ovarian cancer tissue using HE4 antibody (primary antibody at 1:100) 100 μg Anmelden zum Anzeigen 10 bis 15 Tage
$531.13
Details
Maus Kaninchen Unkonjugiert ELISA, IHC (p), WB Western blot analysis of HE4 using anti-HE4 antibody . Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.  Lane 1: rat testis tissue lysates,  Lane 2: rat brain tissue lysates, Lane 3: rat thymus tissue lysates, Lane 4: mouse testis tissue lysates, Lane 5: mouse brain tissue lysates, Lane 6: mouse thymus tissue lysates, Lane 7: mouse HEPA1-6 whole cell lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-HE4 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 ug/mL overnight at 4℃, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for HE4 at approximately 19KD. The expected band size for HE4 is at 13KD. IHC analysis of HE4 using anti-HE4 antibody .HE4 was detected in paraffin-embedded section of mouse lung tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1ug/ml rabbit anti-HE4 Antibody  overnight at 4℃. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37℃. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen. 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Human Maus Unkonjugiert IHC, IHC (p), WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of HE4 expression in 22RV1 whole cell lysates ( Lane 1). HE4 at 25KD was detected using rabbit anti- HE4 Antigen Affinity purified polyclonal antibody (Catalog # ) at 0.5 ??g/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Maus Unkonjugiert ELISA, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.08 KDa) . Dilution: 1:500~1000 Detection limit for recombinant GST tagged WFDC2 is approximately 0.03ng/ml as a capture antibody. 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$461.00
Details
Human Ziege Unkonjugiert ELISA 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details
Human Ziege Unkonjugiert ELISA, WB Western Blot: HE4/WFDC2 Antibody [NBP1-49888] - HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human WFDC2 with C-terminal MYC tag probed (1ug/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed (1mg/ml) in Lane B. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Hund Ziege Unkonjugiert EIA, WB HEK293 lysate (10 µg protein in RIPA buffer) overexpressing Human WFDC2 with C-terminal MYC tag probed with AP22455PU-N (1 µg/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed with AP22455PU-N (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus Unkonjugiert WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$242.88
Details

Am meisten referenzierte anti-WFDC2 Antikörper

  1. Human Monoclonal WFDC2 Primary Antibody für ELISA, WB - ABIN564522 : Yuan, Duan, Yang, Luo, Xi: Detection of serum human epididymis secretory protein 4 in patients with ovarian cancer using a label-free biosensor based on localized surface plasmon resonance. in International journal of nanomedicine 2012 (PubMed)

  2. Human Polyclonal WFDC2 Primary Antibody für ELISA, WB - ABIN4276002 : Huhtinen, Suvitie, Hiissa, Junnila, Huvila, Kujari, Setälä, Härkki, Jalkanen, Fraser, Mäkinen, Auranen, Poutanen, Perheentupa: Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts. in British journal of cancer 2009 (PubMed)

Weitere Antikörper gegen WFDC2 Interaktionspartner

Human WAP Four-Disulfide Core Domain 2 (WFDC2) Interaktionspartner

  1. A panel of three tumor markers CYFRA 21.1, HE4 and ProGRP may play a role for discriminating LC from benign lung disease and subtyping as SCLC.

  2. Serum Smac (zeige DIABLO Antikörper) expression level was significantly lower in the EAOC group than in the control group and benign ovarian tumor group (P< 0.05), while HE4 and CA125 (zeige MUC16 Antikörper) expression levels were significantly higher in the EAOC group than the other two groups.

  3. This study demonstrated that altered expression of HE4 may involve in tumorigenesis in the uterine cervix. Our findings also suggested the presence of a correlation between HE4 expression and the invasive potential of uterine tumors. Therefore it may be thought that the tissue expression of HE4 can be used to differentiate high grade intraepithelial tumors from carcinomas.

  4. High serum HE4 level is associated with epithelial ovarian cancer.

  5. Use of HE4 instead of CA125 (zeige MUC16 Antikörper) did not significantly improve diagnostic performance of risk of malignancy indices 1-4 in patients with an adnexal mass

  6. The significant effect of the normalization of the HE4 marker after therapy and 50% reduction of HE4 levels before interval cytoreductive surgery on PFS and OS confirmed that HE4 might be an independent prognostic factor of treatment response.

  7. HE4 could help with the differentiation of prognostically varied patient groups as well as with the decision-making process associated with the development of individual treatment plans

  8. Studied serum levels of Parkinson's disease-associated protein 7 (DJ-1 (zeige PARK7 Antikörper)) and human epididymis protein 4 (HE4) in endometrial cancer (EC) patients and healthy controls. The median serum concentrations of DJ-1 (zeige PARK7 Antikörper) and HE4 were found to be significantly higher in EC patients compared to controls.

  9. HE4 is a biomarker for ovarian cancer recurrence [review]

  10. Numerous studies indicated that HE4 is able to promote cancer progression and drug resistance. These observations strongly suggest that HE4 may play a significant role in cancer recurrence through its bioactivity in the regulation of malignant behavior at the cellular level. Overall, available data shows that high serum HE4 levels correlate well with ovarian cancer recurrence. [review]

Mouse (Murine) WAP Four-Disulfide Core Domain 2 (WFDC2) Interaktionspartner

  1. Causal testing implicates Wfdc2 and Hdac3 (zeige HDAC3 Antikörper) as novel genes affecting high density lipoprotein levels

WFDC2 Antigen-Profil

Protein Überblick

This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.

Genbezeichner und Symbole assoziert mit WFDC2

  • WAP four-disulfide core domain 2 (WFDC2) Antikörper
  • WAP four-disulfide core domain 2 (wfdc2) Antikörper
  • WAP four-disulfide core domain 2 (Wfdc2) Antikörper
  • 1600023A02Rik Antikörper
  • BE-20 Antikörper
  • CE4 Antikörper
  • dJ461P17.6 Antikörper
  • EDDM4 Antikörper
  • HE4 Antikörper
  • re4 Antikörper
  • si:ch211-153a8.3 Antikörper
  • WAP5 Antikörper
  • WFDC2 Antikörper
  • WFDC3 Antikörper

Bezeichner auf Proteinebene für WFDC2

WAP four-disulfide core domain 2 , WAP four-disulfide core domain 3 , WAP four-disulfide core domain protein 2 , WAP domain containing protein HE4-V4 , epididymal protein 4 , epididymal secretory protein E4 , epididymis-specific, whey-acidic protein type, four-disulfide core , major epididymis-specific protein E4 , putative protease inhibitor WAP5 , WAP domain-containing protein HE4 , epididymal secretory protein 4 , epididymal protein BE-20

GENE ID SPEZIES
419300 Gallus gallus
458283 Pan troglodytes
618044 Bos taurus
100074492 Ornithorhynchus anatinus
556600 Danio rerio
396987 Sus scrofa
10406 Homo sapiens
67701 Mus musculus
286888 Rattus norvegicus
403919 Canis lupus familiaris
100009206 Oryctolagus cuniculus
Ausgewählte Anbieter für anti-WFDC2 (WFDC2) Antikörper
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