anti-Vitamin K-dependent protein C (PROC) Antikörper

PROC encodes a vitamin K-dependent plasma glycoprotein. Zusätzlich bieten wir Ihnen PROC Kits (67) und PROC Proteine (37) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PROC 25268 P31394
PROC 19123 P33587
PROC 5624 P04070
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Top anti-PROC Antikörper auf antikoerper-online.de

Showing 10 out of 216 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti-Protein C antibody, Western blotting Lane 1: JURKAT Cell Lysate Lane 2: CEM Cell Lysate Lane 3: SMMC Cell Lysate Lane 4: HELA Cell Lysate Anti-Protein C antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Pferd Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-PROC Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  MCF7 cell lysate Host:  Rabbit  Target Name:  PROC  Sample Type:  Human Adult Placenta  Antibody Dilution:  1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB WB Suggested Anti-PRH2 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Heart 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$319.00
Details
Ziege Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-PROC Antibody Titration:  2.5ug/ml  Positive Control:  Transfected 293T 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of Protein C expression in HeLa (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: Molt-4 , 10% SDS PAGE antibody diluted at 1:3000 100 μL Anmelden zum Anzeigen 3 bis 4 Tage
$466.18
Details
Human Kaninchen Unkonjugiert ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Human Colon, antibody was diluted at 1:100. 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Human Ziege Unkonjugiert ELISA, IEP, IHC, IHC (p) Vessels, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Liver, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 250 μg Anmelden zum Anzeigen 11 bis 14 Tage
$727.83
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
$493.17
Details

Am meisten referenzierte anti-PROC Antikörper

  1. Human Polyclonal PROC Primary Antibody für IHC (p), WB - ABIN3044486 : Liu, An, Liu, Li, Tang, Chen: Mouse lung slices: An ex vivo model for the evaluation of antiviral and anti-inflammatory agents against influenza viruses. in Antiviral research 2015 (PubMed)
    Show all 10 Pubmed References

  2. Cow (Bovine) Polyclonal PROC Primary Antibody für EIA, RIA - ABIN613777 : Satou, Nishi, Hishinuma, Hosoda, Kangawa, Sugimoto: Identification of activated protein C as a ghrelin endopeptidase in bovine plasma. in The Journal of endocrinology 2014 (PubMed)

Weitere Antikörper gegen PROC Interaktionspartner

Mouse (Murine) Vitamin K-dependent protein C (PROC) Interaktionspartner

  1. Data show that activated protein C signals via protease activated receptors PAR2 (zeige F2RL1 Antikörper)/PAR3 (zeige F2RL2 Antikörper) to expand Treg cells, mitigating the disease in mice.

  2. insulin (zeige INS Antikörper) and aPC (zeige APC Antikörper) converge on a common spliced-X-box binding protein-1 (zeige XBP1 Antikörper) (sXBP1) signaling pathway to maintain endoplasmic reticulum (ER) homeostasis.

  3. loss of the convertase furin (zeige FURIN Antikörper) or PC5 (zeige PCSK5 Antikörper)/6 in hepatocytes results in a approximately 30% decrease in APC (zeige APC Antikörper) levels, with no significant contribution from PACE4 (zeige PCSK6 Antikörper). We conclude that prior convertase cleavage of protein C in hepatocytes is critical for its thrombin (zeige F2 Antikörper) activation.

  4. APC (zeige APC Antikörper) modifies pulmonary fibrosis by limiting thrombin (zeige F2 Antikörper)-dependent macrophage recruitment.

  5. Small interfering RNA-mediated silencing of protein C in apolipoprotein E (zeige APOE Antikörper)-deficient mice creates a condition that allows the occurrence of spontaneous atherothrombosis.

  6. These findings reveal a novel biological function and mechanism of the protein C pathway in which protein S and the aPC (zeige APC Antikörper)-cleaved form of fV are cofactors for anti-inflammatory cell signaling by aPC (zeige APC Antikörper) in the context of endotoxemia and infection

  7. activated PC-EPCR-PAR1 signaling promotes hematopoietic stem cell retention in bone marrow.

  8. impaired EPCR (zeige PROCR Antikörper)/protein C-binding interactions not only result in procoagulant and proinflammatory effects, but also impact hematopoiesis

  9. SOD prevents thrombomodulin (zeige THBD Antikörper) methionine oxidation, promotes protein C activation, and protects against arterial and venous thrombosis in mice.

  10. sPLA2 (zeige PLA2G2A Antikörper)-V plays a thrombogenic role by impairing the ability of EPCR (zeige PROCR Antikörper) to promote protein C activation.

Human Vitamin K-dependent protein C (PROC) Interaktionspartner

  1. The fusion protein recapitulates the functional and structural properties of the thrombin (zeige F2 Antikörper)-thrombomodulin (zeige THBD Antikörper) complex, prolongs the clotting time by generating pharmacological quantities of activated protein C and effectively diagnoses protein C deficiency in human plasma.

  2. Polymorphisms of F2, PROC, PROZ, and F13A1 Genes are Associated With Recurrent Spontaneous Abortion in Chinese Han Women.

  3. Laboratory tests and direct sequencing of PROC and SERPINC1 (zeige SERPINC1 Antikörper) were conducted for the patient and his family members. Coagulation tests revealed that the patient presented type I antithrombin (zeige SERPINC1 Antikörper) deficiency combined with decreased protein C activity resulting from a small insertion mutation c.848_849insGATGT in SERPINC1 (zeige SERPINC1 Antikörper) and a short deletion variant c.572_574delAGA in PROC.

  4. Using protein C-factor VII (zeige TH Antikörper) chimera demonstrate that APC (zeige APC Antikörper) light chain amino acid residues outside the EPCR (zeige PROCR Antikörper)-binding site enable cytoprotective PAR1 (zeige MARK2 Antikörper) signaling.

  5. We recently identified a venous thrombosis patient whose plasma level of protein C antigen is normal, but its anticoagulant activity is only 34 % of the normal level. Genetic analysis revealed that the proband and her younger brother carry a novel heterozygous mutation c.346G>A, p.Gly74Ser (G74S) in PROC.

  6. Developed functional protein S assays that measure both the activated protein C- and TFPI (zeige TFPI Antikörper)-cofactor activities of protein S in plasma, which are hardly if at all affected by the FV Leiden mutation.

  7. Protein C seems inversely associated with mortality in patients with advanced prostate, lung and pancreatic cancer. Further research should validate protein C as a biomarker for mortality, and explore the effects of protein C on progression of cancer.

  8. Genetically higher protein C was associated with a lower risk of ischaemic heart disease.

  9. EPCR (zeige PROCR Antikörper) occupancy recruits G-protein coupled receptor kinase 5 (zeige GRK5 Antikörper), thereby inducing beta-arrestin-2 (zeige ARRB2 Antikörper) biased PAR1 (zeige MARK2 Antikörper) signaling by both APC (zeige APC Antikörper) and thrombin (zeige F2 Antikörper). In

  10. A novel mutation of A309V in PROC was determined in a family of two patients with late onset protein C deficiency

Cow (Bovine) Vitamin K-dependent protein C (PROC) Interaktionspartner

  1. Activated protein c is a ghrelin (zeige GHRL Antikörper) endopeptidase.

  2. Activated protein C(APC (zeige APC Antikörper)) combined with protein S(PS) had significant antithrombotic effect. APC (zeige APC Antikörper) combined with PS prolonged clotting time. Dependence on APC (zeige APC Antikörper)-cofactor activity of PS for expression of anticoagulant activity by APC (zeige APC Antikörper).

PROC Antigen-Profil

Protein Überblick

This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.

Genbezeichner und Symbole assoziert mit PROC

  • protein C (inactivator of coagulation factors Va and VIIIa), a (proca) Antikörper
  • protein C, inactivator of coagulation factors Va and VIIIa (PROC) Antikörper
  • protein C (inactivator of coagulation factors Va and VIIIa) (PROC) Antikörper
  • protein C, inactivator of coagulation factors Va and VIIIa S homeolog (proc.S) Antikörper
  • protein C, inactivator of coagulation factors Va and VIIIa (proc) Antikörper
  • vitamin K-dependent protein C (CpipJ_CPIJ000393) Antikörper
  • vitamin K-dependent protein C (CpipJ_CPIJ002754) Antikörper
  • vitamin K-dependent protein C (CpipJ_CPIJ003717) Antikörper
  • vitamin K-dependent protein C (CpipJ_CPIJ003718) Antikörper
  • vitamin K-dependent protein C (CpipJ_CPIJ014440) Antikörper
  • vitamin K-dependent protein C (CpipJ_CPIJ018032) Antikörper
  • vitamin K-dependent protein C (CpipJ_CPIJ018737) Antikörper
  • protein C, inactivator of coagulation factors Va and VIIIa (Proc) Antikörper
  • protein C (Proc) Antikörper
  • APC Antikörper
  • MGC64425 Antikörper
  • PC Antikörper
  • PROC Antikörper
  • PROC1 Antikörper
  • si:ch1073-188c16.3 Antikörper
  • THPH3 Antikörper
  • THPH4 Antikörper
  • zgc:63987 Antikörper

Bezeichner auf Proteinebene für PROC

protein C , procl , anticoagulant protein C , vitamin K-dependent protein C , protein C (inactivator of coagulation factors Va and VIIIa) , vitamin K-dependent protein C-like , autoprothrombin IIA , blood coagulation factor XIV , inactivator of coagulation factors Va, VIII , catalytic region , protein C (precursor of vitamin K-dependent serine protease)

GENE ID SPEZIES
393327 Danio rerio
395085 Gallus gallus
459593 Pan troglodytes
100302329 Ovis aries
380116 Xenopus laevis
548476 Xenopus (Silurana) tropicalis
100231143 Taeniopygia guttata
100448857 Pongo abelii
6031231 Culex quinquefasciatus
6033948 Culex quinquefasciatus
6035053 Culex quinquefasciatus
6035054 Culex quinquefasciatus
6047546 Culex quinquefasciatus
6052150 Culex quinquefasciatus
6052641 Culex quinquefasciatus
25268 Rattus norvegicus
19123 Mus musculus
5624 Homo sapiens
281428 Bos taurus
101096161 Felis catus
476104 Canis lupus familiaris
100051306 Equus caballus
396954 Sus scrofa
100009223 Oryctolagus cuniculus
699077 Macaca mulatta
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