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The protein encoded by VGLL1 binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus. Zusätzlich bieten wir Ihnen VGLL1 Proteine (4) und und viele weitere Produktgruppen zu diesem Protein an.
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VGLL1 expression is associated with a triple-negative basal-like phenotype in breast cancer
Vgll1 interacts with TEAD4 in a manner similar to the transcription coactivators, as well as oncogenes YAP and TAZ, despite having a varied primary sequence. Vgll1 has the potential to promote cancer progression.
The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus. It may thus function as a specific coactivator for the mammalian TEFs.
, transcription cofactor vestigial-like protein 1
, vestigial like 1 homolog
, vestigial like 1 (Drosophila)
, vestigial like 1
, vestigial-related factor