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May act as an inhibitor of TGF-beta signaling (By similarity). Zusätzlich bieten wir Ihnen Vasorin Proteine (14) und Vasorin Kits (11) und viele weitere Produktgruppen zu diesem Protein an.
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VASN stimulates tumor progression and angiogenesis.
Expression levels of ST3Gal1 and TGFB1 were high in breast cancer tumors samples and positively correlated with each other. Shorter relapse-free survival associated with lower expression of VASN and combination of low VASN with high ST3GAL1 yielded even higher risk of recurrence. Findings illustrated a feedback regulatory loop in which TGF-beta1 upregulates ST3Gal1 to circumvent the negative impact of VASN.
Vasorin acts as a switch to augment Notch signaling under hypoxic conditions.
confirmed for the first time that HepG2-derived VASN can be transferred to human umbilical vein endothelial cells (HUVECs) via receptor mediated endocytosis of exosomes, at least in part through HSPGs
results suggest that down-regulation of vasorin expression contributes to neointimal formation after vascular injury and that vasorin modulates cellular responses to pathological stimuli in the vessel wall [vasorin]
Vasn regulates folliculogenesis, maintenance of the ovarian reserve and ovulation.
Study characterized the expression pattern of Vasn during mouse embryonic development; with various distinct expression domains, results indicate important roles for Vasn e.g., in the developing skeletal system, the kidneys, and the lungs.
ATIA is an HIF-1 target that regulates mitochondrial redox pathways.
May act as an inhibitor of TGF-beta signaling (By similarity).
, protein slit-like 2
, slit-like 2
, Slit-like 2