anti-Vacuolar Protein Sorting 35 Homolog (S. Cerevisiae) (vps35) Antikörper

vps35 belongs to a group of vacuolar protein sorting (VPS) genes. Zusätzlich bieten wir Ihnen vps35 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
vps35 65114 Q9EQH3
vps35 55737 Q96QK1
vps35 25479  
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Top anti-vps35 Antikörper auf antikoerper-online.de

Showing 10 out of 44 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Chinese Hamster Ziege Unkonjugiert ICC, IF, IHC (p), IHC, ELISA, WB ABIN250175 staining (1µg/ml) of Human Brain lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. ABIN250175 staining of paraffin embedded Human Testis showing A) Epithelial cells of the epididymis and B) Some leydig cells. Microwaved antigen retrieval with A)Tris/EDTA buffer pH9 at 3?g/ml or B)Citrate buffer pH6 at 10ug/ml., HRP-staining. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$514.63
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Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit <br /> Target Name: Vps35 <br /> Sample Tissue: Mouse Lung lysates <br /> Antibody Dilution: 1.0 µg/mL 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert IHC, ELISA, WB ABIN185182 staining (1 ug/ml) of Human Brain lysate (RIPA buffer, 35 ug total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. ABIN185182 staining of paraffin embedded Human Testis showing A) Epithelial cells of the epididymis and B) Some leydig cells.  Microwaved antigen retrieval with A)Tris/EDTA buffer pH9 at 3 ug/ml or B)Citrate buffer pH6 at 10ug/ml., HRP-staining. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
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Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB IHC-P Image VPS35 antibody [C3], C-term detects VPS35 protein at cytoplasm and membrane on human colon carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded colon carcinoma. VPS35 antibody [C3], C-term , dilution: 1:250. WB Image VPS35 antibody [C3], C-term detects VPS35 protein by western blot analysis. A. 30 μg A549 whole cell extract B. 30 μg H1299 whole cell extract C. 30 μg HCT116 whole cell extract 7.5 % SDS-PAGE VPS35 antibody [C3], C-term , dilution: 1:1000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
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Human Kaninchen Unkonjugiert IHC, IHC (p), IP, WB Immunoprecipitation: VPS35 Antibody  - Immunoprecipitation of VPS35 protein from HeLa whole cell extracts using 5 ug of VPS35 antibody. Western blot analysis was performed using VPS35 antibody. EasyBlot anti-Rabbit IgG was used as a secondary reagent. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$514.63
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Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: VPS35 Antibody [NBP1-31069] - Methanol-fixed HCT116, using VPS35 antibody at 1:500 dilution. Western Blot: VPS35 Antibody [NBP1-31069] - Sample(30 ug of whole cell lysate)A:H1299B:HeLa S3 C:Hep G2 D:MOLT4 E:Raji 7. 5% SDS PAGE, antibody diluted at 1:500. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$514.63
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Rind (Kuh) Ziege Unkonjugiert EIA, IF, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 10 bis 12 Tage
$455.40
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Rind (Kuh) Ziege Unkonjugiert IHC (p), ELISA, WB Human Breast, Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
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Human Maus Unkonjugiert ELISA, WB VPS35 monoclonal antibody (M02), clone 2D3. Western Blot analysis of VPS35 expression in human colon. VPS35 monoclonal antibody (M02), clone 2D3. Western Blot analysis of VPS35 expression in HeLa. 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
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Rind (Kuh) Ziege Unkonjugiert ICC, IHC, ELISA, WB ABIN2560746 staining of paraffin embedded Human Testis showing A) Epithelial cells of the epididymis and B) Some leydig cells. Microwaved antigen retrieval with A)Tris/EDTA buffer pH9 at 3µg/ml or B)Citrate buffer pH6 at 10ug/ml., HRP-staining. ABIN2560746 (0.1µg/ml) staining of Human Cerebellum lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μL Anmelden zum Anzeigen 16 Days
$444.57
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vps35 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine)
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Human
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Rat (Rattus)
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Am meisten referenzierte anti-vps35 Antikörper

  1. Chinese Hamster Polyclonal vps35 Primary Antibody für ICC, IF - ABIN250175 : Hong, Yang, Zhang, Niu, Li, Zhao, Liu: The retromer component SNX6 interacts with dynactin p150(Glued) and mediates endosome-to-TGN transport. in Cell research 2009 (PubMed)
    Show all 15 Pubmed References

  2. Human Monoclonal vps35 Primary Antibody für ELISA, WB - ABIN565910 : Prosser, Tran, Schooley, Wendland, Ngsee: A novel, retromer-independent role for sorting nexins 1 and 2 in RhoG-dependent membrane remodeling. in Traffic (Copenhagen, Denmark) 2010 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal vps35 Primary Antibody für IHC, ELISA - ABIN185182 : Zhang, Yu, Gao, Fu, Dai, Zhao, Zheng, Zhao: Cloning and characterization of human VPS35 and mouse Vps35 and mapping of VPS35 to human chromosome 16q13-q21. in Genomics 2001 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal vps35 Primary Antibody für IHC, IHC (p) - ABIN4365839 : Yin, Liu, He, Zhou, Yuan, Zhao: Vps35-dependent recycling of Trem2 regulates microglial function. in Traffic (Copenhagen, Denmark) 2016 (PubMed)

Weitere Antikörper gegen vps35 Interaktionspartner

Fruit Fly (Drosophila melanogaster) Vacuolar Protein Sorting 35 Homolog (S. Cerevisiae) (vps35) Interaktionspartner

  1. The in vivo effects of P316S, D620N and L774M of VPS35 using Drosophila as a model, were investigated.

  2. The findings of this study indicate that the VPS35 may play a crucial role in alpha-synucle in degradation by modulating the maturation of cathepsin D (zeige CTSD Antikörper) and might thereby contribute to the pathogenesis of the disease.

  3. overexpression of Vps35 ameliorates the pathogenic mutant LRRK2 eye phenotype in a Drosophila model of Parkinson's disease

  4. Vps35 negatively regulates actin (zeige ACTB Antikörper) polymerisation, and genetic interactions suggest that some of the endocytic and signalling defects of vps35 mutants are due to this function

Mouse (Murine) Vacuolar Protein Sorting 35 Homolog (S. Cerevisiae) (vps35) Interaktionspartner

  1. Vps35 D620N allele is a partial-loss-of-function allele and that such a genetic predisposition and age-related alterations in the nigrostriatal dopamine system cooperatively influence the pathogenesis of PARK17.

  2. Results provide evidence for a critical role of Vps35 in mouse corneal dystrophy; suggest that SLC4A11 (zeige SLC4A11 Antikörper) appears to be a Vps35/retromer cargo, and Vps35-regulation of SLC4A11 (zeige SLC4A11 Antikörper) trafficking may underlie Vps35/retromer regulation of corneal dystrophy.

  3. Our study suggests that Vps35/retromer is responsible for recycling of Trem2 (zeige TREM2 Antikörper) in the regulation of microglial function such as proinflammatory responses.

  4. Using in vivo knockdown of the critical retromer component VPS35, we demonstrate a specific role for this endosomal sorting complex in the trafficking of AMPA (zeige GRIA3 Antikörper) receptors during NMDA-receptor-dependent LTP (zeige SCP2 Antikörper) at mature hippocampal synapses.

  5. the data presented in this manuscript demonstrate a critical function of VPS35 in regulating PTH1R (zeige PTH1R Antikörper) trafficking. This event and VPS35-interaction with PPP1R14C (zeige PPP1R14C Antikörper) appear to be essential for turning off PTH1R's endosomal signaling, and promoting PTH1R (zeige PTH1R Antikörper)-mediated catabolic response and bone remodeling.

  6. These results provide evidence for VPS35's function in promoting spine maturation, which is likely through increasing AMPA (zeige GRIA3 Antikörper) receptor targeting to the postsynaptic membrane.

  7. Deletion of the VPS35 gene in dopamine (DA) neurons resulted in Parkinson disease-like deficits, including loss of DA neurons and accumulation of alpha-synuclein.

  8. These results suggest that VPS35 deficiency or mutation promotes Parkinson Disease (PD) pathogenesis, and reveals a crucial pathway, VPS35-Lamp2a-alpha-synuclein, to prevent PD pathogenesis.

  9. Our studies reveal unexpected genetic and functional interactions between VPS35 and EIF4G1, two seemingly unrelated PD genes, and functionally connect them to alpha-synuclein pathobiology in yeast, worms, and mouse.

  10. Vps35 is necessary for mouse retinal ganglion cell survival and regeneration.

Human Vacuolar Protein Sorting 35 Homolog (S. Cerevisiae) (vps35) Interaktionspartner

  1. Present data support a role for perturbed VPS35 and retromer function in the pathogenesis of Parkinson's disease.

  2. These findings provide new mechanistic insights into the role of VPS35 in the regulation of AIMP2 (zeige AIMP2 Antikörper) levels and cell death.

  3. The retromer complex is a highly conserved membrane trafficking assembly composed of three proteins - Vps26 (zeige VPS26A Antikörper), Vps29 (zeige VPS29 Antikörper) and Vps35, which are impaired in neurodegenerative diseases. (Review)

  4. It could interact with DRD1 (zeige DRD1 Antikörper) and regulate DRD1 (zeige DRD1 Antikörper) cell surface recycling, as well as DRD1 (zeige DRD1 Antikörper)- mediated dopamine signaling.

  5. The absence of mutations in VPS35 genes reveals that they are uncommon causes of Parkinson disease in Brazil

  6. VPS35 has been associated with autosomal dominant forms of Parkinson's disease with a high but incomplete penetrance .

  7. results lend further support to the notion that VPS35-DLP1 (zeige DNM1L Antikörper) interaction is key to the retromer-dependent recycling of mitochondrial DLP1 (zeige DNM1L Antikörper) complex during mitochondrial fission and provide a novel therapeutic target to control excessive fission and associated mitochondrial deficits.

  8. Silencing VPS35 increased N-Ras's association with cytoplasmic vesicles, diminished GTP (zeige AK3 Antikörper) loading of Ras, and inhibited mitogen-activated protein kinase (zeige MAPK1 Antikörper) signaling and growth of N-Ras (zeige NRAS Antikörper)-dependent melanoma cells.

  9. deletion of VPS35 in yeast (vps35Delta) leads to a dose-dependent growth defect towards copper. This increased sensitivity could be rescued by transformation with yeast wild-type VPS35 but not by the expression of a construct harboring the yeast equivalent (i.e. D686N) of the most commonly identified VPS35-associated Parkinson disease mutation, p.D620N

  10. the Vps35 R524W-containing retromer has a decreased endosomal association, which can be partially rescued by R55, a small molecule previously shown to stabilize the retromer complex, supporting the potential for future targeting of the retromer complex in the treatment of Parkinson disease.

vps35 Antigen-Profil

Protein Überblick

This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex.

Genbezeichner und Symbole assoziert mit vps35

  • VPS35, retromer complex component (VPS35) Antikörper
  • vacuolar protein sorting-associated protein 35 (Tc00.1047053511367.170) Antikörper
  • vacuolar protein sorting-associated protein 35 (Tb10.70.5460) Antikörper
  • vacuolar protein sorting-associated protein 35 (BBOV_IV009740) Antikörper
  • vacuolar protein sorting-associated protein 35 (CC1G_12185) Antikörper
  • vacuolar protein sorting-associated protein 35 (PTRG_08682) Antikörper
  • vacuolar protein sorting-associated protein 35 (CMU_017400) Antikörper
  • vacuolar protein sorting-associated protein 35 (PHATR_43830) Antikörper
  • vacuolar protein sorting-associated protein 35 (MCYG_00751) Antikörper
  • vacuolar protein sorting-associated protein 35 (MGYG_01212) Antikörper
  • hypothetical protein (PGTG_10018) Antikörper
  • vacuolar protein sorting-associated protein 35 (Tsp_09825) Antikörper
  • vacuolar protein sorting 35 homolog (S. cerevisiae) (VPS35) Antikörper
  • VPS35, retromer complex component (vps35) Antikörper
  • Vacuolar protein sorting 35 (Vps35) Antikörper
  • VPS35 retromer complex component L homeolog (vps35.L) Antikörper
  • VPS35 retromer complex component (vps35) Antikörper
  • vacuolar protein sorting 35 homolog (S. cerevisiae) (vps35) Antikörper
  • vacuolar protein sorting 35 (EHI_086580) Antikörper
  • vacuolar protein sorting 35 (EHI_002990) Antikörper
  • vacuolar protein sorting 35 (EHI_041950) Antikörper
  • vacuolar protein sorting 35 (EHI_096520) Antikörper
  • Vacuolar protein sorting 35 (Bm1_44045) Antikörper
  • vacuolar protein sorting 35 (LOC100285267) Antikörper
  • VPS35 retromer complex component (Vps35) Antikörper
  • 23.m05999 Antikörper
  • AI647796 Antikörper
  • bZ34G2.3 Antikörper
  • CG5625 Antikörper
  • DKFZp459E1510 Antikörper
  • Dmel\\CG5625 Antikörper
  • dvps35 Antikörper
  • MEM3 Antikörper
  • MGC81959 Antikörper
  • PARK17 Antikörper
  • si:rp71-34g2.3 Antikörper
  • vps35 Antikörper
  • wu:fa66e03 Antikörper
  • wu:fb95c08 Antikörper
  • zgc:136268 Antikörper

Bezeichner auf Proteinebene für vps35

vacuolar protein sorting-associated protein 35 , vacuolar protein sorting 35 homolog (S. cerevisiae) , vacuolar protein sorting 35 homolog , vacuolar protein sorting 35-like , CG5625-PA , CG5625-PB , Vps35-PA , Vps35-PB , vacuolar protein sorting 35 , Vacuolar protein sorting 35 , maternal embryonic message 3 , maternal-embryonic 3 , vesicle protein sorting 35 , hVPS35

GENE ID SPEZIES
415750 Gallus gallus
465139 Pan troglodytes
475346 Canis lupus familiaris
717394 Macaca mulatta
3551850 Trypanosoma cruzi strain CL Brener
3663050 Trypanosoma brucei brucei strain 927/4 GUTat10.1
5479130 Babesia bovis T2Bo
6004947 Coprinopsis cinerea okayama7130
6346969 Pyrenophora tritici-repentis Pt-1C-BFP
6995620 Cryptosporidium muris RN66
7203962 Phaeodactylum tricornutum CCAP 1055/1
9223543 Arthroderma otae CBS 113480
10032453 Arthroderma gypseum CBS 118893
10544762 Puccinia graminis f. sp. tritici CRL 75-36-700-3
10907761 Trichinella spiralis
100015669 Monodelphis domestica
100056512 Equus caballus
100174173 Pongo abelii
100351202 Oryctolagus cuniculus
100367783 Saccoglossus kowalevskii
100551222 Meleagris gallopavo
100559729 Anolis carolinensis
100599794 Nomascus leucogenys
100623578 Sus scrofa
37536 Drosophila melanogaster
446307 Xenopus laevis
549980 Xenopus (Silurana) tropicalis
561697 Danio rerio
3405460 Entamoeba histolytica HM-1:IMSS
3407291 Entamoeba histolytica HM-1:IMSS
3410852 Entamoeba histolytica HM-1:IMSS
3411245 Entamoeba histolytica HM-1:IMSS
6103693 Brugia malayi
100285267 Zea mays
65114 Mus musculus
55737 Homo sapiens
25479 Rattus norvegicus
521864 Bos taurus
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