anti-Vacuolar Protein Sorting 26 Homolog A (S. Pombe) (VPS26A) Antikörper

VPS26A belongs to a group of vacuolar protein sorting (VPS) genes. Zusätzlich bieten wir Ihnen Vacuolar Protein Sorting 26 Homolog A (S. Pombe) Proteine (13) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
VPS26A 9559 O75436
VPS26A 30930 P40336
VPS26A 361846 Q6AY86
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Top anti-Vacuolar Protein Sorting 26 Homolog A (S. Pombe) Antikörper auf antikoerper-online.de

Showing 10 out of 77 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Ziege Unkonjugiert ELISA, WB ABIN185172 staining (1 ug/ml) of Human Kidney lysate (RIPA buffer, 35 ug total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. 100 μg 6 bis 7 Tage
$429.84
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB WB Image Sample(30 ug whole cell lysate) A:293T B:A431, C:HeLa S3, D:Hep G2 , 10% SDS PAGE antibody diluted at 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded A549 xenograft, using VPS26, antibody at 1:500 dilution. 100 μL 3 bis 4 Tage
$466.18
Details
Huhn Ziege Unkonjugiert ELISA, WB 100 μg 11 bis 14 Tage
$610.50
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Huhn Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$551.83
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Human Kaninchen Unkonjugiert EIA, WB   0.4 mL 4 bis 8 Tage
$522.50
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Rind (Kuh) Ziege Unkonjugiert WB   0.1 mg 4 bis 8 Tage
$462.00
Details
Human Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$419.83
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of VPS26A Antibody in HepG2 cell line lysates (35ug/lane) Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with VPS26A Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL 2 bis 3 Tage
$515.63
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB 200 μL 12 bis 14 Tage
$438.90
Details

Am meisten referenzierte anti-Vacuolar Protein Sorting 26 Homolog A (S. Pombe) Antikörper

  1. Human Polyclonal VPS26A Primary Antibody für ELISA, WB - ABIN547236 : Haft, de la Luz Sierra, Bafford, Lesniak, Barr, Taylor: Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes. in Molecular biology of the cell 2000 (PubMed)

  2. Human Monoclonal VPS26A Primary Antibody für ICC, IF - ABIN4365823 : Aranda, Rathjen, Johannes, Fernández-Hernando: MicroRNA 199a-5p Attenuates Retrograde Transport and Protects against Toxin-Induced Inhibition of Protein Biosynthesis. in Molecular and cellular biology 2019 (PubMed)

Weitere Antikörper gegen Vacuolar Protein Sorting 26 Homolog A (S. Pombe) Interaktionspartner

Human Vacuolar Protein Sorting 26 Homolog A (S. Pombe) (VPS26A) Interaktionspartner

  1. We investigated the modification of air pollution and diabetes association by a genetic risk score covering 63 T2D genes. Five single variants near GRB14, UBE2E2, PTPRD, VPS26A and KCNQ1 showed nominally significant interactions with PM10 (P<0.05). Our results suggest that genetic risk for T2D may modify susceptibility to air pollution through alterations in insulin sensitivity.

  2. The retromer complex is a highly conserved membrane trafficking assembly composed of three proteins - Vps26, Vps29 and Vps35, which are impaired in neurodegenerative diseases. (Review)

  3. X-ray crystallographic analysis of a 4-component complex comprising the VPS26 & VPS35 subunits of retromer, sorting nexin SNX3, & recycling signal from the divalent cation transporter DMT1-II; analysis identifies a binding site for canonical recycling signals at the interface between VPS26 & SNX3; shows cooperative interactions among the VPS subunits, SNX3 & cargo that couple signal-recognition to membrane recruitment.

  4. Mutagenesis studies coupled with coimmunoprecipitations revealed that retromer-mediated trafficking requires the Env cytoplasmic tail that we show binds directly to retromer components Vps35 and Vps26.

  5. provides molecular insights into the essential role of Vps26 and Vps35 in Rab7-mediated recruitment of the core retromer complex

  6. This study demonstrated that Genetic variability of VPS26A in parkinsonism.

  7. Mutations in the gene composing the retromer cargo recognition subunit are not a common cause of Parkinson's disease.

  8. Mutations in VPS26A are not a frequent cause of Parkinson's disease.

  9. VPS26A binding increases the affinity of the SNX27 PDZ domain for PDZ- binding motifs by an order of magnitude, revealing cooperativity in cargo selection.

  10. Rabankyrin-5 interacts with EHD1 and Vps26 to regulate endocytic trafficking and retromer function

  11. Colocalization of Vps26 paralogues with different endosomally located Rab proteins shows prolonged association of Vps26B-retromer with maturing endosomes relative to Vps26A-retromer.

  12. These observations indicate that the mammalian retromer complex assembles by sequential association of SNX1/2 and Vps26-Vps29-Vps35 subcomplexes on endosomal membranes and that SNX1 and SNX2 play interchangeable but essential roles.

  13. Membrane recruitment of the cargo-selective retromer subcomplex VPS35/29/26 is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5.

Mouse (Murine) Vacuolar Protein Sorting 26 Homolog A (S. Pombe) (VPS26A) Interaktionspartner

  1. VPS26A binding increases the affinity of the SNX27 PDZ domain for PDZ- binding motifs by an order of magnitude, revealing cooperativity in cargo selection.

  2. Vps26 is implicated in regulating Vps35p membrane association, therefore Vps26 plays a role in cargo recognition of the cytoplasmic coat retromer complex.

  3. These results revealed that the retromer complex could be formed from different Vps26 isoforms in a tissue-specific manner.

Vacuolar Protein Sorting 26 Homolog A (S. Pombe) (VPS26A) Antigen-Profil

Protein Überblick

This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms.

Genbezeichner und Symbole assoziert mit VPS26A

  • VPS26, retromer complex component A (VPS26A) Antikörper
  • VPS26 retromer complex component A (Vps26a) Antikörper
  • vacuolar protein sorting 26A (VPS26A) Antikörper
  • vacuolar protein sorting 26 (LOC692917) Antikörper
  • vacuolar protein sorting homolog26 (vpsh26) Antikörper
  • vacuolar protein sorting 26 homolog A (S. pombe) pseudogene (LOC100147400) Antikörper
  • VPS26 retromer complex component A L homeolog (vps26a.L) Antikörper
  • VPS26, retromer complex component A (Vps26a) Antikörper
  • vacuolar protein sorting 26 homolog A (S. pombe) (vps26a) Antikörper
  • AA407240 Antikörper
  • DKFZp459G2011 Antikörper
  • hb58 Antikörper
  • hbeta58 Antikörper
  • MNC6.7 Antikörper
  • MNC6_7 Antikörper
  • pep8a Antikörper
  • vacuolar protein sorting 26A Antikörper
  • vps26 Antikörper
  • vps26a Antikörper
  • wu:fc67e06 Antikörper
  • zgc:56673 Antikörper

Bezeichner auf Proteinebene für VPS26A

vacuolar protein sorting-associated protein 26A , vesicle protein sorting 26A , H beta 58 , h58 protein , mVPS26 , vacuole protein sorting 26 , vacuolar protein sorting 26 A , vacuolar protein sorting 26 homolog A (S. pombe) , vacuolar protein sorting-associated protein 26A-like , vacuolar protein sorting 26 , vacuolar protein sorting homolog26 , zmh1 , 5C06F05 , PCO142195 , p-5C06F05 , PCO142195_ov , uaz5c06f05(gfu) , Zea mouse H58 homolog1 , vacuolar protein sorting-associated protein 26A-A , vesicle protein sorting 26A-A , vacuolar protein sorting 26 homolog A , Vesicle protein sorting 26A

GENE ID SPEZIES
9559 Homo sapiens
30930 Mus musculus
510574 Bos taurus
423696 Gallus gallus
479233 Canis lupus familiaris
717371 Macaca mulatta
748846 Pan troglodytes
835435 Arabidopsis thaliana
100174023 Pongo abelii
100385858 Callithrix jacchus
692917 Bombyx mori
100282332 Zea mays
361846 Rattus norvegicus
100147400 Equus caballus
100596592 Nomascus leucogenys
432091 Xenopus laevis
100726769 Cavia porcellus
393881 Danio rerio
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