V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) Proteine (MAFB)

The protein encoded by MAFB is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. Zusätzlich bieten wir Ihnen MAFB Antikörper (52) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
MAFB 9935 Q9Y5Q3
MAFB 54264 P54842
MAFB 16658 P54841
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Showing 8 out of 9 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Hefe Huhn His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,830.67
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Hefe Xenopus tropicalis His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,847.17
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Hefe Cynomolgus His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,867.33
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,867.33
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Hefe Zebrafisch His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,970.00
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MAFB Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Rat (Rattus)

Mouse (Murine)

Weitere Proteine zu V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) (MAFB) Interaktionspartnern

Human V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) (MAFB) Interaktionspartner

  1. This study further confirmed that the targeted single nucleotide polymorphisms at MAFB were associated with Non-syndromic cleft lip with or without cleft palate case-parent trios from Western Han Chinese population

  2. These results suggest that MAFB and MAFF play critical roles in the antitumor effects of retinoids by regulating the expression of retinoid target genes such as TFPI2 and can be promising for developing therapies to combat HCC invasion.

  3. MAFB enhanced leukemogenesis by the naturally occurring Notch1 mutants, decreased disease latency, and increased disease penetrance.

  4. USP5 regulates c-Maf stability and multiple myeloma cell survival.

  5. Data suggest that SUMOylated MAFB promotes colorectal cancer tumorigenesis through cell cycle regulation.

  6. these results demonstrate that MAFB critically determines the acquisition of the anti-inflammatory transcriptional and functional profiles of human macrophages

  7. The present study demonstrated that miR-152 was downregulated in NPC tissues and cell lines. In addition, miR-152 expression and MAFB knockdown inhibited cell proliferation, migration and invasion, and miR-152 suppressed the expression of MAFB at the mRNA and protein levels.

  8. Epidermal differentiation gene regulatory networks are controlled by MAF and MAFB.

  9. Loss of MAFB Function Causes Duane Syndrome, Aberrant Extraocular Muscle Innervation, and Inner-Ear Defects.

  10. Results indicate a hepatocellular carcinoma (HCC) regulatory pathway involving MafB transcription factor and cyclin D1, the dysfunction of which drives proliferative character in HCC.

  11. DNMT3A R882 mutation is associated with elevated expression of MAFB and M4/M5 immunophenotype of acute myeloid leukemia blasts.

  12. MAFB is a regulator and a marker of adipose tissue inflammation, a process that subsequently causes insulin resistance

  13. MAFB represents a unique signature and likely important regulator of the primate islet beta-cell.

  14. The rs2902940A allele carriers in the MAFB conferred a decreased serum ApoAI level in controls and an increased risk of coronary artery disease and ischemic stroke.

  15. Gata3 interacted with Gcm2 and MafB, two known transcriptional regulators of parathyroid development, and synergistically stimulated the PTH promoter.

  16. MiR-223 negatively regulates the growth and migration of NPC cells via reducing MAFB expression, and this finding provides a novel insight into understanding miR-223 regulation mechanism in nasopharyngeal carcinoma tumorigenesis.

  17. rs6065259 was the most important single nucleotide polymorphism in MAFB (OR6065259-AA=0.45; 95% CI: 0.28 to 0.71; p=0.0027), followed by rs13041247; no association was found between rs11696257 and NSCLP.

  18. These findings indicate that only a few transactivation domain-specific mutations within MAFB cause multicentric carpotarsal osteolysis.

  19. Mafb is responsible for executing one branch of the SGN differentiation program orchestrated by the Gata3 transcriptional network

  20. MAFA, MAFB, NKX6.1, and PDX1 activity provides a gauge of islet beta cell function, with loss of MAFA (and/or MAFB) representing an early indicator of beta cell inactivity

Zebrafish V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) (MAFB) Interaktionspartner

  1. Vegfc signaling increases mafba expression to control downstream transcription

Mouse (Murine) V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) (MAFB) Interaktionspartner

  1. MafB appears to play an important role in secondary hyperparathyroidism by regulation of parathyroid hormone and cyclin D2 expression.

  2. The expression of the first protein in the classical complement pathway C1q is important for mediating efferocytosis and is reduced in Mafb-deficient macrophages.

  3. present findings indicate that MafB enhances efferocytosis by regulating Axl expression in RAW264.7 macrophages

  4. Therefore, MafB promotes differentiation in postmitotic keratinocytes and simultaneously has potential to promote growth when ectopically expressed in undifferentiated basal keratinocytes.

  5. MAFB localized in Leydig and Sertoli cells in testes at E18.5 while it localized in Leydig cells, Sertoli cells, and pachytene spermatocytes in adult testes. Examination revealed that MAFB-deficient testes developed normally by E18.5, and spermatogenesis was not disrupted in adult mice. MAFB MAFB might be critical for phagocytosis activity of Sertoli cells.

  6. MafB controls endothelial sprouting in vitro and in vivo in postnatal retinal angiogenesis.

  7. Macrophage-specific inhibition of MafB may destabilize atherosclerotic plaques in advanced lesions

  8. a protective role of oxLDL-associated LPS on beta-cell function during hyperlipidemia by inducing miR-155-5p, which prevents the upregulation of MafB and beta-to-alpha-cell reprogramming.

  9. Increased mafB at the common myeloid progenitor stage steers their lineage away from the megakaryocyte erythrocyte progenitor production and drives the terminal fate of these progenitors to form macrophages vs. dendritic cells, causing anemia, monocytosis, and dendritic cell loss. It is a transcriptional activator of M-CSFR and a repressor of transferrin receptors, promoting macrophages and plasmacytoid dendritic cells.

  10. An elevation of MSR1 levels in infiltrating myeloid cells observed 3 d after experimental stroke was dependent on the transcription factor Mafb. Mafb deficiency in infiltrating myeloid cells caused impaired clearance of DAMPs, more severe inflammation, and exacerbated neuronal injury in a murine model of ischemic stroke.

  11. a Mafb-driven Cre strain was generated to determine whether any dendritic cells (DCs) identified by Zbtb46-green fluorescent protein expression originate from a Mafb-expressing population.

  12. MafB deletion in maternal beta-cells also produced GDM, with inadequate beta-cell expansion accompanied by failure to induce PRLR-dependent target genes regulating beta-cell proliferation. These results unveil molecular roles for PRLR signaling in orchestrating the physiologic expansion of maternal beta-cells during pregnancy.

  13. MafB play an important role in promoting hindbrain choroid plexus development during embryogenesis

  14. Meanwhile, the observed reduction in the phagocytic activity of the MafB-shRNA-expressing cells was attenuated by ectopic expression of Fcgr3. Together, the results presented here indicate that MafB influences the phagocytic activity of macrophages by promoting Fcgr3, but not Fcgr2b, expression.

  15. Loss of MAFB Function Causes Duane Syndrome, Aberrant Extraocular Muscle Innervation, and Inner-Ear Defects.

  16. MafB and c-Maf have different expression patterns in macrophages, suggesting differences in function.

  17. MAFB is an important transcription factor involved in lymphangiogenesis.

  18. Study provides insights to elucidate mechanisms of gene regulation through androgen response elements present in Mafb 3'UTR for a better understanding of the processes of urethral masculinization.

  19. It contributes to the development of hyperglycemia in the Mafa-deficient background in adults as well as in embryos.

  20. MafB is only essential to islet alpha-cell activity and not beta-cell.

MAFB Protein Überblick

Protein Überblick

The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This gene contains no introns.

Genbezeichner und Symbole assoziert mit MAFB

  • MAF bZIP transcription factor B (MAFB)
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B (mafb)
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B S homeolog (mafb.S)
  • MAF bZIP transcription factor B (Mafb)
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba (mafba)
  • v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (Mafb)
  • b-maf Protein
  • kr Protein
  • Kreisler Protein
  • Krml Protein
  • Krml1 Protein
  • Maf-B Protein
  • mafb Protein
  • MCTO Protein
  • MGC108453 Protein
  • val Protein
  • valentino Protein
  • wu:fc22d11 Protein
  • wu:fj82a09 Protein
  • XMafB Protein

Bezeichner auf Proteinebene für MAFB

v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) , v-maf musculoaponeurotic fibrosarcoma oncogene protein B , v-maf musculoaponeurotic fibrosarcoma oncogene homolog B , Transcription factor MafB , bzip transcription factor mafB , transcription factor MafB , Kreisler maf-related leucine zipper homolog , MAFB/Kreisler basic region/leucine zipper transcription factor , Kreisler maf-related leucine zipper homolog (b-maf) , maf-B , transcription factor Maf-1 , v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B , transcription factor Val , valentino , Kreisler (maf-related) leucine zipper protein , V-maf musculoaponeurotic fibrosarcoma oncogene homolog B , segmentation protein Kr

GENE ID SPEZIES
469941 Pan troglodytes
554333 Ovis aries
595086 Xenopus (Silurana) tropicalis
399156 Xenopus laevis
9935 Homo sapiens
532376 Bos taurus
54264 Rattus norvegicus
30210 Danio rerio
16658 Mus musculus
419173 Gallus gallus
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