V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) Proteine (MAFB)

The protein encoded by MAFB is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. Zusätzlich bieten wir Ihnen MAFB Antikörper (51) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
MAFB 9935 Q9Y5Q3
MAFB 54264 P54842
MAFB 16658 P54841
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Showing 8 out of 9 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Hefe Huhn His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,830.67
Details
Hefe Xenopus tropicalis His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,847.17
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,867.33
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Hefe Cynomolgus His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,867.33
Details
Hefe Zebrafisch His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,970.00
Details

MAFB Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Rat (Rattus)

Mouse (Murine)

Weitere Proteine zu V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) (MAFB) Interaktionspartnern

Human V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) (MAFB) Interaktionspartner

  1. These results suggest that MAFB and MAFF (zeige MAFF Proteine) play critical roles in the antitumor effects of retinoids by regulating the expression of retinoid target genes such as TFPI2 (zeige TFPI2 Proteine) and can be promising for developing therapies to combat HCC (zeige FAM126A Proteine) invasion.

  2. MAFB enhanced leukemogenesis by the naturally occurring Notch1 (zeige NOTCH1 Proteine) mutants, decreased disease latency, and increased disease penetrance.

  3. USP5 (zeige USP5 Proteine) regulates c-Maf (zeige MAF Proteine) stability and multiple myeloma cell survival.

  4. Data suggest that SUMOylated MAFB promotes colorectal cancer tumorigenesis through cell cycle regulation.

  5. these results demonstrate that MAFB critically determines the acquisition of the anti-inflammatory transcriptional and functional profiles of human macrophages

  6. The present study demonstrated that miR (zeige MLXIP Proteine)-152 was downregulated in NPC (zeige NPC1 Proteine) tissues and cell lines. In addition, miR (zeige MLXIP Proteine)-152 expression and MAFB knockdown inhibited cell proliferation, migration and invasion, and miR (zeige MLXIP Proteine)-152 suppressed the expression of MAFB at the mRNA and protein levels.

  7. Epidermal differentiation gene regulatory networks are controlled by MAF (zeige MAF Proteine) and MAFB.

  8. Loss of MAFB Function Causes Duane Syndrome, Aberrant Extraocular Muscle Innervation, and Inner-Ear Defects.

  9. Results indicate a hepatocellular carcinoma (HCC (zeige FAM126A Proteine)) regulatory pathway involving MafB transcription factor and cyclin D1 (zeige CCND1 Proteine), the dysfunction of which drives proliferative character in HCC (zeige FAM126A Proteine).

  10. DNMT3A (zeige DNMT3A Proteine) R882 mutation is associated with elevated expression of MAFB and M4/M5 immunophenotype of acute myeloid leukemia (zeige BCL11A Proteine) blasts.

Zebrafish V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) (MAFB) Interaktionspartner

  1. Vegfc (zeige VEGFC Proteine) signaling increases mafba expression to control downstream transcription

Mouse (Murine) V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog B (Avian) (MAFB) Interaktionspartner

  1. The expression of the first protein in the classical complement pathway C1q is important for mediating efferocytosis and is reduced in Mafb-deficient macrophages.

  2. present findings indicate that MafB enhances efferocytosis by regulating Axl (zeige AXL Proteine) expression in RAW264.7 macrophages

  3. Therefore, MafB promotes differentiation in postmitotic keratinocytes and simultaneously has potential to promote growth when ectopically expressed in undifferentiated basal keratinocytes.

  4. MAFB localized in Leydig and Sertoli cells in testes at E18.5 while it localized in Leydig cells, Sertoli cells, and pachytene spermatocytes in adult testes. Examination revealed that MAFB-deficient testes developed normally by E18.5, and spermatogenesis was not disrupted in adult mice. MAFB MAFB might be critical for phagocytosis activity of Sertoli cells.

  5. MafB controls endothelial sprouting in vitro and in vivo in postnatal retinal angiogenesis.

  6. Macrophage-specific inhibition of MafB may destabilize atherosclerotic plaques in advanced lesions

  7. a protective role of oxLDL-associated LPS (zeige TLR4 Proteine) on beta-cell function during hyperlipidemia by inducing miR (zeige MLXIP Proteine)-155-5p, which prevents the upregulation of MafB and beta-to-alpha-cell reprogramming.

  8. Increased mafB at the common myeloid progenitor stage steers their lineage away from the megakaryocyte erythrocyte progenitor production and drives the terminal fate of these progenitors to form macrophages vs. dendritic cells, causing anemia, monocytosis, and dendritic cell loss. It is a transcriptional activator of M-CSFR (zeige CSF1R Proteine) and a repressor of transferrin (zeige Tf Proteine) receptors, promoting macrophages and plasmacytoid dendritic cells.

  9. An elevation of MSR1 (zeige MSR1 Proteine) levels in infiltrating myeloid cells observed 3 d after experimental stroke was dependent on the transcription factor Mafb. Mafb deficiency in infiltrating myeloid cells caused impaired clearance of DAMPs, more severe inflammation, and exacerbated neuronal injury in a murine model of ischemic stroke.

  10. a Mafb-driven Cre strain was generated to determine whether any dendritic cells (DCs) identified by Zbtb46 (zeige ZNF340 Proteine)-green fluorescent protein expression originate from a Mafb-expressing population.

MAFB Protein Überblick

Protein Überblick

The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This gene contains no introns.

Genbezeichner und Symbole assoziert mit MAFB

  • MAF bZIP transcription factor B (MAFB)
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B (mafb)
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B S homeolog (mafb.S)
  • MAF bZIP transcription factor B (Mafb)
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba (mafba)
  • v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (Mafb)
  • b-maf Protein
  • kr Protein
  • Kreisler Protein
  • Krml Protein
  • Krml1 Protein
  • Maf-B Protein
  • mafb Protein
  • MCTO Protein
  • MGC108453 Protein
  • val Protein
  • valentino Protein
  • wu:fc22d11 Protein
  • wu:fj82a09 Protein
  • XMafB Protein

Bezeichner auf Proteinebene für MAFB

v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) , v-maf musculoaponeurotic fibrosarcoma oncogene protein B , v-maf musculoaponeurotic fibrosarcoma oncogene homolog B , Transcription factor MafB , bzip transcription factor mafB , transcription factor MafB , Kreisler maf-related leucine zipper homolog , MAFB/Kreisler basic region/leucine zipper transcription factor , Kreisler maf-related leucine zipper homolog (b-maf) , maf-B , transcription factor Maf-1 , v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B , transcription factor Val , valentino , Kreisler (maf-related) leucine zipper protein , V-maf musculoaponeurotic fibrosarcoma oncogene homolog B , segmentation protein Kr

GENE ID SPEZIES
469941 Pan troglodytes
554333 Ovis aries
595086 Xenopus (Silurana) tropicalis
399156 Xenopus laevis
9935 Homo sapiens
532376 Bos taurus
54264 Rattus norvegicus
30210 Danio rerio
16658 Mus musculus
419173 Gallus gallus
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