anti-Uromodulin (UMOD) Antikörper

UMOD encodes uromodulin, the most abundant protein in normal urine. Zusätzlich bieten wir Ihnen Uromodulin Kits (64) und Uromodulin Proteine (21) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
UMOD 7369 P07911
UMOD 22242 Q91X17
UMOD 25128 P27590
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Top anti-Uromodulin Antikörper auf

Showing 10 out of 185 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-UMOD Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>THP-1 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-UMOD Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>THP-1 cell lysate WB Suggested Anti-UMOD <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: THP-1 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert WB Western blot analysis of Uromodulin expression in HEK293T (A), THP1 (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
Human Kaninchen Unkonjugiert IHC (p), WB UMOD Antibody (Center) (ABIN658177) western blot analysis in MDA-MB453 cell line lysates (35 µg/lane). This demonstrates the UMOD antibody detected the UMOD protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse kidney tissue labeled with Anti-MCKD2/UMOD Polyclonal Antibody, Unconjugated (ABIN678473) at 1:200 followed by conjugation to the secondary antibody and DAB staining L1 rat kidney lysates, L2 human kidney carcinoma lysates probed (ABIN678473) Anti MCKD2/UMOD Polyclonal, Unconjugated at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band and observed band size: 65kD. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
Hund Maus FITC EIA, IHC (fro), IF, IHC (p)   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
Hund Maus Unkonjugiert EIA, IHC (fro), IF, IHC (p)   0.25 mg Anmelden zum Anzeigen 6 bis 8 Tage
Hund Maus HRP EIA, IHC (fro), IF, IHC (p), RIA   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
Human Maus Unkonjugiert IP, ELISA, WB Detection limit for recombinant GST tagged UMOD is 0.3 ng/ml as a capture antibody. Western Blot analysis of UMOD expression in transfected 293T cell line by UMOD monoclonal antibody (M03), clone 3F10.<br><br>Lane 1: UMOD transfected lysate (Predicted MW: 66.7 KDa).<br>Lane 2: Non-transfected lysate.<br> 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage

UMOD Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Uromodulin Antikörper

  1. Human Polyclonal Uromodulin Primary Antibody für IHC (fro), ELISA - ABIN2476682 : Conner, Mansour: Serotonin receptor-mediated activation of adenylate cyclase in the neuroblastoma NCB.20: a novel 5-hydroxytryptamine receptor. in Molecular pharmacology 1990 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal Uromodulin Primary Antibody für IP, ELISA - ABIN521253 : Jou, Fang, Chen, Chen, Cheng, Shen, Liao, Tsai: Proteomic study of renal uric acid stone. in Urology 2012 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal Uromodulin Primary Antibody für IF, IHC (p) - ABIN521251 : Larkin, Zhang, Godfrey, Molostvov, Zehnder, Rabbani, Thornalley: Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes. in PLoS ONE 2013 (PubMed)

  4. Human Polyclonal Uromodulin Primary Antibody für IF (p) - ABIN729800 : Cho, Song, Oh, Kim, Ko, Lee, Jo: Fate of Neutrophils during the Recovery Phase of Ischemia/Reperfusion Induced Acute Kidney Injury. in Journal of Korean medical science 2017 (PubMed)

Weitere Antikörper gegen Uromodulin Interaktionspartner

Human Uromodulin (UMOD) Interaktionspartner

  1. Studied genetic association of uromodulin SNP in kidney function of patients with hypertension and cardiovascular disease.

  2. Single-nucleotide polymorphism in UMOD gene is associated with type 2 diabetes.

  3. UMOD gene variants in humans fulfill the criteria for ascribing a gene as causal of Hypertension.

  4. The missense mutation p.142R>R/Q in the uromodulin gene in patients with cast Nephropathy in Multiple Myeloma.

  5. Data show that one SNP (rs183962941), located in a non-coding region of uromodulin protein (UMOD), was nominally associated with end-stage renal disease (ESRD).

  6. THP appears to participate directly in complement inactivation by its ability to act as a cofactor for C3b degradation.

  7. High urinary uromodulin levels are associated with lower risk for UTI (zeige AMBP Antikörper) in older community-dwelling adults independent of traditional UTI (zeige AMBP Antikörper) risk factors.

  8. The uromodulin-CFH (zeige CFH Antikörper) interaction enhanced the cofactor activity of CFH (zeige CFH Antikörper) for factor I-mediated cleavage of C3b to inactivated C3b.

  9. These findings suggest that the levels of urinary microvesicle-bound uromodulin are associated with the severity of diabetic kidney disease.

  10. Data strongly suggest that the uromodulin ancestral allele, driving higher urinary excretion of uromodulin, has been kept at a high frequency because of its protective effect against urinary tract infections

Mouse (Murine) Uromodulin (UMOD) Interaktionspartner

  1. results strongly suggest that the progressive worsening of kidney functions reflects the accumulation of the deleterious effects of the misfolded mutant THP and the compensatory responses

  2. Endoplasmic reticulum stress and apoptosis are key features in a mouse model of kidney disease driven by the uromodulin p.Cys147Trp mutation.

  3. Consistently, pathway enrichment analysis indicates that mutant uromodulin expression affects ER function and protein homeostasis.

  4. we show that Tamm-Horsfall protein deficiency stimulates proximal epithelial activation of the Interleukin-23/Interleukin-17 (zeige IL17A Antikörper) axis and systemic neutrophilia.

  5. TNFalpha (zeige TNF Antikörper) regulates uromodulin expression in a homeostatic setting, but the impact of TNFalpha (zeige TNF Antikörper) on uromodulin during kidney injury is superseded by other factors that could inhibit HNF1beta (zeige HNF1B Antikörper)-mediated expression of uromodulin.

  6. AGP was more effective in limiting hepatic inflammation and maintaining perfusion than saline or HAS, in both endotoxemic and septic mice. AGP sequestration of LPS (zeige TLR4 Antikörper) may contribute to its anti-inflammatory effects.

  7. UMOD upregulates TRPV5 (zeige TRPV5 Antikörper) by decreasing caveolin-1 (zeige CAV1 Antikörper) dependent endocytosis of TRPV5 (zeige TRPV5 Antikörper).

  8. UMOD regulates sodium uptake in the thick ascending limb of the loop of Henle by modulating the effect of tumor necrosis factor-alpha (zeige TNF Antikörper) on NKCC2A expression, making UMOD an important determinant of blood pressure control.

  9. Genetic susceptibility link to hypertension and chronic kidney disease to uromodulin expression and uromodulin's effect on salt reabsorption in the kidney.

  10. Using an ischemia-reperfusion model of murine acute kidney injury, we show that, while THP expression in thick ascending loop is downregulated at the peak of injury, it is significantly upregulated 48 h after.

Cow (Bovine) Uromodulin (UMOD) Interaktionspartner

Uromodulin (UMOD) Antigen-Profil

Protein Überblick

This gene encodes uromodulin, the most abundant protein in normal urine. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. Uromodulin may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of uromodulin in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the autosomal dominant renal disorders medullary cystic kidney disease-2 (MCKD2) and familial juvenile hyperuricemic nephropathy (FJHN). These disorders are characterized by juvenile onset of hyperuricemia, gout, and progressive renal failure. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform.

Genbezeichner und Symbole assoziert mit anti-Uromodulin (UMOD) Antikörper

  • uromodulin (UMOD) Antikörper
  • uromodulin (Umod) Antikörper
  • ADMCKD2 Antikörper
  • FJHN Antikörper
  • HNFJ Antikörper
  • HNFJ1 Antikörper
  • MCKD2 Antikörper
  • THGP Antikörper
  • THP Antikörper
  • urehr4 Antikörper

Bezeichner auf Proteinebene für anti-Uromodulin (UMOD) Antikörper

uromodulin , Tamm-Horsfall urinary glycoprotein , uromucoid , THP , tamm-Horsfall urinary glycoprotein , uromodulin (uromucoid, Tamm-Horsfall glycoprotein) , Urmodulin (Tamm-Horsfall protein) , uromucoid, human : Tamm-Horsfall glycoprotein

695883 Macaca mulatta
100026222 Monodelphis domestica
7369 Homo sapiens
403510 Canis lupus familiaris
22242 Mus musculus
25128 Rattus norvegicus
281567 Bos taurus
100730507 Cavia porcellus
100173805 Pongo abelii
100511125 Sus scrofa
100342440 Oryctolagus cuniculus
Ausgewählte Anbieter für anti-Uromodulin (UMOD) Antikörper
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