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Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Zusätzlich bieten wir Ihnen UBE2Q2 Antikörper (55) und und viele weitere Produktgruppen zu diesem Protein an.
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UBE2Q1 hypomethylation is associated with Colorectal Cancer.
The newly characterized human gene, UBE2Q2, may have implications for the pathogenesis of acute lymphoblastic leukemia.
In the 21 breast cancer cases investigated, a high increase in UBE2Q2 expression was found in 8 breast cancers (38.1%), a moderately increased UBE2Q2 expression was observed in 7 cases (33.3%), and no sig. changes were detected in 6 cases (28.6%).
Found high expression levels of UBE2Q2 in human head and neck carcinoma cell lines and cancer tissues; found the level of UBE2Q2 is decreased in cell lines and cancer tissues that have resistance to CDDP or docetaxel.
the novel LOC92912 gene is characterized. It is over-expressed in hypopharyngeal tumours. Its functions may be linked with the cytoskeleton; it may represent a new target for cancer therapeutics.
Inhibition of the UBE2Q2 protein causes cells to undergo a prolonged prophase arrest suggesting that UBE2Q2 normally functions to antagonize an early mitotic checkpoint.
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination (By similarity).
ubiquitin carrier protein Q2
, ubiquitin-conjugating enzyme E2 Q2
, ubiquitin-protein ligase Q2
, ubiquitin-conjugating enzyme E2Q (putative) 2
, ubiquitin-conjugating enzyme E2Q 2
, ubiquitin-conjugating enzyme UBCi
, ubiquitin-conjugating enzyme E2Q family member 2
, ubiquitin conjugating enzyme E2Q family member 2 L homeolog