Ubiquitin Specific Peptidase 48 Proteine (USP48)

USP48 encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Zusätzlich bieten wir Ihnen USP48 Antikörper (39) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
USP48 84196 Q86UV5
Maus USP48 USP48 170707 Q3V0C5
Ratte USP48 USP48 362636 Q76LT8
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage

USP48 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,

Am meisten referenzierte USP48 Proteine

  1. Human USP48 Protein expressed in Wheat germ - ABIN1324823 : Schweitzer, Naumann: CSN-associated USP48 confers stability to nuclear NF-?B/RelA by trimming K48-linked Ub-chains. in Biochimica et biophysica acta 2015 (PubMed)

Weitere Proteine zu Ubiquitin Specific Peptidase 48 (USP48) Interaktionspartnern

Human Ubiquitin Specific Peptidase 48 (USP48) Interaktionspartner

  1. USP48 and BRAF mutations have a role in Cushing's disease

  2. USP48 inactivation reduces chromosomal instability of Fanconi anemia (FA)-defective cells. Our results highlight a role for USP48 in controlling DNA repair and suggest it as a potential target that could be therapeutically exploited for FA.

  3. In contrast to other deubiquitinating enzymes (DUBs) that have been previously implicated in the regulation of Mdm2 protein stability, USP48 did not induce Mdm2 stabilization by significantly reducing Mdm2 ubiquitination levels.

  4. down-regulation of USP48 increases E-cadherin expression and epithelial barrier integrity through reducing TRAF2 stability

  5. study reveals that the USP48-Gli1 regulatory axis is critical for glioma cell proliferation and glioblastoma tumorigenesis.

  6. Data suggest that ubiquitin specific protease-48 (USP48) promotes genome stability by antagonizing BRCA1 E3 ligase function.

  7. this study demonstrates that USP48 controls the Ubiquitin/proteasome-system-dependent turnover of activated NF-kappaB/RelA in the nucleus.

  8. Northern blot analysis revealed a single USP31 transcript of approximately 4 kb, which was primarily expressed in the testis and lung.

  9. The Overexpression of USP31 in HEK 293T cells inhibited TNFalpha, CD40, LMP1, TRAF2, TRAF6 and IKKbeta-mediated NF-kappaB activation, but did not inhibit Smad-mediated transcription activation.

  10. data demonstrate a crucial role for the dynamic interaction between D3R and USP48 in the regulation of NHE3 expression and function

USP48 Protein Überblick

Protein Überblick

This gene encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Genbezeichner und Symbole assoziert mit USP48

  • ubiquitin specific peptidase 48 (USP48)
  • ubiquitin specific peptidase 48 (Usp48)
  • ubiquitin specific peptidase 48 (usp48)
  • 2810449C13Rik Protein
  • AI115503 Protein
  • BC021769 Protein
  • D330022K21Rik Protein
  • MGC135142 Protein
  • RAP1GA1 Protein
  • synUSP Protein
  • Usp31 Protein
  • USP48 Protein
  • zgc:112364 Protein

Bezeichner auf Proteinebene für USP48

deubiquitinating enzyme 48 , ubiquitin carboxyl-terminal hydrolase 48 , ubiquitin specific protease 31 , ubiquitin specific protease 48 , ubiquitin thioesterase 48 , ubiquitin thiolesterase 48 , ubiquitin-specific-processing protease 48 , synaptic ubiquitin-specific protease , ubiquitin specific peptidase 48 , ubiquitin carboxyl-terminal hydrolase 48-like

84196 Homo sapiens
170707 Mus musculus
362636 Rattus norvegicus
456602 Pan troglodytes
769457 Gallus gallus
100141158 Bos taurus
478198 Canis lupus familiaris
100023231 Monodelphis domestica
100058232 Equus caballus
100087092 Ornithorhynchus anatinus
100145207 Xenopus (Silurana) tropicalis
100332674 Danio rerio
100402610 Callithrix jacchus
100440156 Pongo abelii
100464072 Ailuropoda melanoleuca
100603457 Nomascus leucogenys
100625904 Sus scrofa
100725391 Cavia porcellus
Ausgewählte Anbieter für USP48 Proteine (USP48)
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