anti-Ubiquitin Specific Peptidase 37 (USP37) Antikörper

Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Zusätzlich bieten wir Ihnen USP37 Proteine (3) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
USP37 57695 Q86T82
USP37 319651 Q8C0R0
USP37    
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Top anti-USP37 Antikörper auf antikoerper-online.de

Showing 10 out of 35 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-USP37 Antibody Titration: 0.2-1 ug/mlPositive Control: 293T cell lysate 100 μL 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, WB UBP37 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35 µg/lane). This demonstrates the UBP37 antibody detected the UBP37 protein (arrow). 0.4 mL 6 bis 8 Tage
$484.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of USP37 expression in HeLa (A), mouse brain (B), rat brain (C) whole cell lysates. 200 μL 13 bis 14 Tage
$487.50
Details
Huhn Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB ABIN6273411 at 1/100 staining Rat brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of USP37 expression in Hela cell lysate,The lane on the left is treated with the antigen-specific peptide. 100 μL 11 bis 12 Tage
$390.77
Details
Human Kaninchen Unkonjugiert WB USP37 antibody used at 1 ug/ml to detect target protein. 50 μg 9 bis 11 Tage
$449.29
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB   100 μg 11 bis 14 Tage
$390.50
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μL 11 bis 14 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Immunohistochemical staining of human hippocampus with USP37 polyclonal antibody  shows distinct cytoplasmic positivity in astrocytes at 1:10-1:20 dilution. 100 μL 11 bis 12 Tage
$577.33
Details
Human Kaninchen Biotin ELISA, WB   200 μL 11 bis 14 Tage
$1,101.83
Details

Am meisten referenzierte anti-USP37 Antikörper

  1. Human Polyclonal USP37 Primary Antibody für ICC, IF - ABIN258290 : Das, Taylor, Gireud, Singh, Lee, Fuller, Ji, Fangusaro, Rajaram, Goldman, Eberhart, Gopalakrishnan: The deubiquitylase USP37 links REST to the control of p27 stability and cell proliferation. in Oncogene 2013 (PubMed)

  2. Human Polyclonal USP37 Primary Antibody für ICC, IF - ABIN4364592 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

Weitere Antikörper gegen USP37 Interaktionspartner

Human Ubiquitin Specific Peptidase 37 (USP37) Interaktionspartner

  1. Findings reveal that USP37 is highly expressed in BCSCs and is correlated with poor prognosis in breast cancer patients. USP37 can regulate the stemness, cell invasion and EMT via Hh pathway, and decreased USP37 confers sensitivity to cisplatin in breast cancer cells.

  2. these findings reveal a role for REST-associated G9a and histone H3K9 methylation in the repression of USP37 expression in medulloblastoma. Reactivation of USP37 by G9a inhibition has the potential for therapeutic applications in REST-expressing medulloblastomas

  3. USP37 interacts with Cdt1 and is able to de-ubiquitinate Cdt1 in vivo and, USP37 is able to regulate the loading of MCM complexes onto the chromatin.

  4. USP37 associates with cohesin and contributes to sister chromatid resolution. Cohesion defects are rescued by expression of an RNAi-resistant USP37, but not the catalytically impaired USP37(C350A) mutant.

  5. USP37 is significantly upregulated in human lung cancer tissues, where its expression is positively correlated with c-Myc protein expression.

  6. These results suggested that the UIMs in USP37 contribute to the full enzymatic activity, but not ubiquitin chain substrate specificity, of USP37 possibly by holding the ubiquitin chain substrate in the proximity of the catalytic core.

  7. our findings of USP37-modulating PLZF/RARA stability and cell transformation suggest that USP37 is a potential therapeutic target for PLZF/RARA-associated APL

  8. USP37 links REST to the control of p27 stability and cell proliferation.

  9. Skp1-Cul1-F-box ubiquitin ligase (SCF(betaTrCP))-mediated destruction of the ubiquitin-specific protease USP37 during G2-phase promotes mitotic entry

  10. The deubiquitinase USP37 binds CDH1 and removes degradative polyubiquitin from cyclin A. USP37 was induced by E2F factors in G1, peaked at G1/S, and was degraded in late mitosis. Phosphorylation of USP37 by CDK2 stimulated its full activity.

USP37 Antigen-Profil

Protein Überblick

Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'- linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-630 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2) (By similarity).

Genbezeichner und Symbole assoziert mit USP37

  • ubiquitin specific peptidase 37 (USP37) Antikörper
  • ubiquitin specific peptidase 37 (usp37) Antikörper
  • ubiquitin specific peptidase 37 (Usp37) Antikörper
  • 4932415L06Rik Antikörper
  • C330008N13Rik Antikörper
  • wu:fi15b04 Antikörper
  • wu:fi38d03 Antikörper
  • zgc:152882 Antikörper
  • zgc:153999 Antikörper

Bezeichner auf Proteinebene für USP37

ubiquitin specific peptidase 37 , ubiquitin specific protease 37 , ubiquitin carboxyl-terminal hydrolase 37-like , deubiquitinating enzyme 37 , tmp_locus_50 , ubiquitin carboxyl-terminal hydrolase 37 , ubiquitin thioesterase 37 , ubiquitin thiolesterase 37 , ubiquitin-specific-processing protease 37 , Deubiquitinating enzyme 37 , Ubiquitin carboxyl-terminal hydrolase 37 , Ubiquitin thiolesterase 37 , Ubiquitin-specific-processing protease 37 , fi15b04 , usp39

GENE ID SPEZIES
459944 Pan troglodytes
701732 Macaca mulatta
100124313 Xenopus (Silurana) tropicalis
100155158 Sus scrofa
100347231 Oryctolagus cuniculus
100389662 Callithrix jacchus
100481404 Ailuropoda melanoleuca
100541053 Meleagris gallopavo
100602108 Nomascus leucogenys
57695 Homo sapiens
319651 Mus musculus
407168 Bos taurus
488523 Canis lupus familiaris
424216 Gallus gallus
768201 Danio rerio
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