Ubiquitin Specific Peptidase 21 Proteine (USP21)

USP21 encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. Zusätzlich bieten wir Ihnen USP21 Antikörper (104) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
USP21 27005 Q9UK80
Maus USP21 USP21 30941 Q9QZL6
USP21 688466 B2GUX4
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage

USP21 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Rat (Rattus)

Weitere Proteine zu Ubiquitin Specific Peptidase 21 (USP21) Interaktionspartnern

Human Ubiquitin Specific Peptidase 21 (USP21) Interaktionspartner

  1. Results from computational biology identified a cancer mutation that inactivates the nuclear export signals of the human deubiquitinase USP21, and leads to the aberrant accumulation of this protein in the nucleus.

  2. Data show that ubiquitin variants (Ubvs) that bind to USP2 or USP21 contain a similar core functional epitope, or "hot spot," consisting mainly of positions that are conserved as the wild type sequence, but also some positions that prefer mutant sequences.

  3. USP21 binds to the promoter region of IL-8 and mediates transcriptional initiation, which regulates the stem-cell like property of human renal cell carcinoma

  4. USP21 interacts with, deubiquitinates and stabilizes BRCA2 to promote efficient RAD51 loading at DNA double-strand breaks.

  5. a critical role of p38-mediated USP21 phosphorylation in regulating STING-mediated antiviral functions and identifies p38-USP21 axis as an important pathway that DNA virus adopts to avoid innate immunity responses.

  6. USP21 recruits and stabilises Gli1 at the centrosome.

  7. USP21 specifically regulates the Lys48-linked polyubiquitination and stability of NANOG

  8. Data show that SUMOylated BANP, E5R, and Nac1 (BEN) domain 3 (BEND3) stabilizes NoRC component TTF-1-interacting protein 5 (Tip5)via association with ubiquitin specific protease 21 (USP21) debiquitinase

  9. The protein stability of IL-33 is maintained by USP21 through deubiquitination

  10. Identification of the E3 deubiquitinase ubiquitin-specific peptidase 21 (USP21) as a positive regulator of the transcription factor GATA3

  11. Study observed a reduction in the number of A549 cells developing a primary cilium upon serum starvation when USP21 was depleted with two independent siRNA oligos.

  12. Study report that USP21 cleaves Ub polymers, and with reduced activity also targets ISG15, but is inactive against NEDD8.

  13. USP21 plays an important role in the down-regulation of TNFalpha-induced NF-kappaB activation through deubiquitinating RIP1.

USP21 Protein Überblick

Protein Überblick

This gene encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation. The encoded protein is also able to release NEDD8, a ubiquitin-like protein, from NEDD8-conjugated proteins. This gene has been referred to as USP16 and USP23 but is now known as USP21. Alternatively spliced transcript variants have been described.

Genbezeichner und Symbole assoziert mit USP21

  • ubiquitin specific peptidase 21 (USP21)
  • ubiquitin specific peptidase 21 (Usp21)
  • ESTM28 Protein
  • Usp16 Protein
  • USP21 Protein
  • Usp23 Protein
  • W53272 Protein

Bezeichner auf Proteinebene für USP21

ubiquitin specific peptidase 21 , Ubiquitin specific peptidase 21 , NEDD8-specific protease , deubiquitinating enzyme 21 , ubiquitin carboxyl-terminal hydrolase 21 , ubiquitin specific protease 21 , ubiquitin thioesterase 21 , ubiquitin thiolesterase 21 , ubiquitin-specific processing protease 21 , ubiquitin-specific protease 16 , ubiquitin-specific-processing protease 21 , ubiquitin specific protease 23 , ubiquitin-specific protease 21

469556 Pan troglodytes
478979 Canis lupus familiaris
719894 Macaca mulatta
100028924 Monodelphis domestica
100066197 Equus caballus
100152455 Sus scrofa
100413038 Callithrix jacchus
100431690 Pongo abelii
100483223 Ailuropoda melanoleuca
100601460 Nomascus leucogenys
27005 Homo sapiens
534273 Bos taurus
30941 Mus musculus
688466 Rattus norvegicus
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