anti-Ubiquitin Specific Peptidase 19 (USP19) Antikörper

Deubiquitinating enzyme that regulates the degradation of various proteins. Zusätzlich bieten wir Ihnen und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
USP19 10869 O94966
USP19 71472 Q3UJD6
USP19 361190 Q6J1Y9
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Top anti-USP19 Antikörper auf antikoerper-online.de

Showing 10 out of 64 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of USP19 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of USP19 expression in Jurkat (A), H9C2 (B) whole cell lysates. 200 μL 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, using USP19 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using USP19 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB 100 μL Verfügbar
$363.46
Details
Human Kaninchen Unkonjugiert ELISA, IHC, IHC (p), WB 50 μL 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL 6 bis 8 Tage
$484.00
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, WB ABIN6275653 staining  NIH-3T3 cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibod ABIN6275653 at 1/100 staining Human lung cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11 bis 12 Tage
$390.77
Details
Human Ziege Unkonjugiert ELISA, WB   0.1 mg 6 bis 7 Tage
$286.39
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of hUSP19-L1304 in Jurkat cell line lysates (35ug/lane) 400 μL 2 bis 3 Tage
$515.63
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB Immunhistochemistry analysis in human heart tissue (Formalin-fixed, Paraffin-embedded) using USP19  Western blot analysis of extracts from NIH-3T3 cells, using USP19 Antibody . The lane on the right is treated with the synthesized peptide. 50 μL 11 bis 13 Tage
$768.40
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg 11 bis 14 Tage
$507.83
Details

Am meisten referenzierte anti-USP19 Antikörper

  1. Human Polyclonal USP19 Primary Antibody für ELISA - ABIN449744 : Zhu, Ménard, Sulea: High incidence of ubiquitin-like domains in human ubiquitin-specific proteases. in Proteins 2007 (PubMed)

  2. Human Polyclonal USP19 Primary Antibody für IP, WB - ABIN256700 : Altun, Zhao, Velasco, Liu, Hassink, Paschke, Pereira, Lindsten: Ubiquitin-specific protease 19 (USP19) regulates hypoxia-inducible factor 1α (HIF-1α) during hypoxia. in The Journal of biological chemistry 2012 (PubMed)

Weitere Antikörper gegen USP19 Interaktionspartner

Human Ubiquitin Specific Peptidase 19 (USP19) Interaktionspartner

  1. HSP90 interacts with Htt-N90 on the N-terminal amphipathic alpha-helix, and then recruits USP19 to modulate the protein level and aggregation of Htt-N90.

  2. USP19 mRNA expression in human adipose tissue was positively correlated with the expression of important adipocyte genes in abdominal fat depots, but not subcutaneous fat depots.

  3. USP19 modulates GR levels and in so doing may modulate both insulin and glucocorticoid signaling, two critical pathways that control protein turnover in muscle and overall glucose homeostasis.

  4. USP19 is a key factor in modulating DNA damage repair by targeting HDAC1/2 K63-linked ubiquitination, cells with deletion or decreased expression of USP19 might cause genome instability and even contribute to tumorigenesis.

  5. findings establish USP19 is a negative regulator of the cellular type I IFN antiviral response to enterovirus 71 (EV71) infection; through the decrease of K63-linked polyubiquitination of TRAF3, USP19 suppresses cellular type I IFN signaling, supporting EV71 propagation in host cells

  6. The regulation of CORO2A through the deubiquitinating activity of USP19 affected the transcriptional repression activity of the retinoic acid receptor (RAR), suggesting that USP19 may be involved in the regulation of RAR-mediated adipogenesis.

  7. HRD1 is a novel substrate for USP19. USP19 negatively regulates the ubiquitination of HRD1 and prevents it from undergoing proteasomal degradation.

  8. USP19 positively regulates autophagy and antiviral immune responses by deubiquitinating Beclin-1.

  9. In conjunction with HSP90, the cytoplasmic USP19 may play a key role in triage decision for the disease-related polyQ-expanded substrates, suggesting a function of USP19 in quality control of misfolded proteins by regulating their protein levels

  10. Expression of USP19 correlates with that of MuRF1 and MAFbx/atrogin-1 in skeletal muscles

  11. These results clarify the role of USP19 in ERAD and suggest a novel DUB regulation that involves chaperone association and membrane integration

  12. USP19 interacts with the ubiquitin ligases SIAH1 and SIAH2, which promote USP19 ubiquitylation and degradation by the proteasome.

  13. experimentally verified the targets heterogeneous nuclear ribonucleoprotein U, phosphatidylinositol-3-OH kinase, the WNK (with-no-lysine) kinase family and USP19 (ubiquitin-specific peptidase 19) as vulnerable nodes in the host cellular defence system against viruses

  14. ubiquitin-specific protease-19 (USP19) interacts with components of the hypoxia pathway including HIF-1alpha and rescues it from degradation independent of its catalytic activity

  15. The USP19 deubiquitinase regulates the stability of c-IAP1 and c-IAP2.

  16. ability of USP19 to regulate cell proliferation and p27(Kip1) levels; complete loss of USP19 function on cell growth may arise as a result of oncogenic transformation of cells.

  17. USP19 is the first example of a membrane-anchored deubiquitinating enzymes involved in the turnover of endoplasmic-reticulum-associated degradation substrates.

Mouse (Murine) Ubiquitin Specific Peptidase 19 (USP19) Interaktionspartner

  1. USP19 is an important regulator of fat development. Its inactivation in mice exerts effects on multiple tissues, which may protect against the negative metabolic effects of high-fat feeding.

  2. USP19 modulates GR levels and in so doing may modulate both insulin and glucocorticoid signaling, two critical pathways that control protein turnover in muscle and overall glucose homeostasis.

  3. Data suggest that expression of Usp19 in skeletal muscle can be regulated by dietary factors; here, supplementation with phytoestrogen daidzein down-regulates Usp19 expression via Esrb signaling and increases skeletal muscle mass. (Usp19 = ubiquitin-specific peptidase 19; Esrb = estrogen receptor beta)

  4. Expression of USP19 correlates with that of MuRF1 and MAFbx/atrogin-1 in skeletal muscles

  5. Deubiquitination by USP19 does modulate muscle cell differentiation and that this function requires the ER-localized isoform and appears to act through regulation of the unfolded-protein response (UPR) signaling.

  6. Data suggest that, in young female mice, 17beta-estradiol upregulates USP19 expression through Esr1 (estrogen receptor alpha) and leads to down-regulation of muscle mass and down-regulation of ubiquitination of muscle proteins.

  7. E2 induces USP19 expression through nuclear ERalpha, (ii) increased USP19-mediated deubiquitinating activity represses myogenesis, and (iii) ERbeta inhibits ERalpha-activated USP19 expression.

  8. study reports that the USP19 deubiquitinating enzyme interacts with and stabilizes KPC1, thereby modulating p27(Kip1) levels and cell proliferation

USP19 Antigen-Profil

Protein Überblick

Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin- dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic- reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non- catalytic manner. Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis.

Genbezeichner und Symbole assoziert mit USP19

  • ubiquitin specific peptidase 19 (usp19) Antikörper
  • ubiquitin specific peptidase 19 (USP19) Antikörper
  • universal stress protein (RR_RS18085) Antikörper
  • ubiquitin carboxyl-terminal hydrolase 19 (PTRG_09611) Antikörper
  • ubiquitin specific peptidase 19 (Usp19) Antikörper
  • 8430421I07Rik Antikörper
  • AI047774 Antikörper
  • MGC145127 Antikörper
  • si:dkey-32e6.9 Antikörper
  • USP19 Antikörper
  • wu:fc26a05 Antikörper
  • Zmynd9 Antikörper

Bezeichner auf Proteinebene für USP19

ubiquitin specific peptidase 19 , ubiquitin-specific protease 19 , ubiquitin specific protease 19 , universal stress protein , ubiquitin carboxyl-terminal hydrolase 19 , ubiquitin carboxyl-terminal hydrolase 19-like , deubiquitinating enzyme 19 , ubiquitin thioesterase 19 , ubiquitin thiolesterase 19 , ubiquitin-specific-processing protease 19 , zinc finger MYND domain-containing protein 9 , ubiquitin-specific processing protease 19

GENE ID SPEZIES
324335 Danio rerio
514587 Bos taurus
707512 Macaca mulatta
780341 Xenopus (Silurana) tropicalis
3127658 Haloarcula marismortui ATCC 43049
6347901 Pyrenophora tritici-repentis Pt-1C-BFP
460364 Pan troglodytes
476627 Canis lupus familiaris
100442002 Pongo abelii
100511534 Sus scrofa
100597821 Nomascus leucogenys
10869 Homo sapiens
71472 Mus musculus
361190 Rattus norvegicus
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