anti-Ubiquitin Specific Peptidase 17-Like 2 (USP17L2) Antikörper

Deubiquitinating enzyme that specifically removes conjugated ubiquitin from CDC25A, thereby playing a key role in cell cycle regulation. Zusätzlich bieten wir Ihnen USP17L2 Proteine (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
USP17L2 377630 Q6R6M4
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Top anti-USP17L2 Antikörper auf antikoerper-online.de

Showing 9 out of 11 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB WB Suggested Anti-USP17L2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human heart WB Suggested Anti-USP17L2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Human heart 100 μL 2 bis 3 Tage
$319.00
Details
Human Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$581.17
Details
Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged DUB3 is approximately 0.3ng/ml as a capture antibody. Western Blot detection against Immunogen (36.74 KDa) . 100 μg 11 bis 12 Tage
$440.00
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL 11 bis 12 Tage
$305.71
Details
Human Maus Unkonjugiert ELISA, WB   100 μg 11 bis 14 Tage
$837.83
Details
Human Kaninchen Unkonjugiert FACS, WB   400 μL 11 bis 14 Tage
$493.17
Details
Human Kaninchen Unkonjugiert WB   100 μL 11 bis 14 Tage
$551.83
Details
Human Maus Unkonjugiert ELISA, WB   100 μg 6 bis 8 Tage
$491.70
Details
Human Kaninchen Unkonjugiert   400 μL 11 bis 16 Tage
$596.97
Details

Weitere Antikörper gegen USP17L2 Interaktionspartner

Human Ubiquitin Specific Peptidase 17-Like 2 (USP17L2) Interaktionspartner

  1. further analysis revealed 2 hemizygous deletions in the grandmother that segregate in several of her affected offspring. The first deletion was found in the UGT2B28 locus, spanning 7 informative sequence variants across at least 14 kb. The second deletion, located in USP17L2, spans 3 informative variants across at least 2 kb. On the whole, the findings of the presents study implicate 2 additional genes in the pathogenesis

  2. our results revealed the essential role of the MGMT-DUB3-MCL1 axis in the chemoresistance of ovarian cancer and identified that a combined treatment with HDACis and PaTrin-2 is an effective method for overcoming chemoresistance in ovarian cancer.

  3. DUB3 promotes BET inhibitor resistance and cancer progression by deubiquitinating BRD4.

  4. Dub3 is identified as a bona fide Snail1 deubiquitinase, which interacts with and stabilizes Snail1.

  5. these data identify DUB3 and USP7 as factors that regulate DNA replication by controlling Geminin protein stability, and suggest that USP7 may be involved in Geminin dysregulation during breast cancer progression.

  6. We provide evidence that DUB3 proteins regulate YAP/TAZ activity by controlling the stability of the E3 ligase ITCH, the LATS kinases and the AMOT family proteins. As a novel Hippo pathway regulator, DUB3 has the potential to act a tumor suppressor by limiting YAP activity.

  7. In cigarette smoke extract-exposed airway epithelial cells and macrophages, HDAC2 is excessively ubiquitinated and degraded in the proteasome attributed to low expression of USP17.

  8. These data indicate that the Dub3 might be a valuable biomarker for the prediction of ovarian cancer prognosis and Dub3 inhibition might be a potential strategy for ovarian cancer treatment.

  9. Dub3 counteracts H2AX E3 ligases RNF8 and RNF168. Moreover, Dub3 and H2AX interact and Dub3 deubiquitinates H2AX in vitro.

  10. Recently, much progress has been made in understanding the physiological functions of cytokine-inducible DUBs such as DUB-1, DUB-2, and DUB-3/USP17, in regulation of cell proliferation and apoptosis in lymphocytes. [review]

  11. As a major regulator of Cdc25A, Dub3 is an example of a transforming ubiquitin hydrolase that subverts a key component of the cell cycle machinery, promoting oncogenic transformation.

  12. human DUB-3, like the murine DUB family members, is transiently induced in response to cytokines and can, when constitutively expressed, block growth factor-dependent proliferation.

  13. Identifies DUB3 as being one of 30 genes with the most variable copy numbers in three human genomes.

USP17L2 Antigen-Profil

Protein Überblick

Deubiquitinating enzyme that specifically removes conjugated ubiquitin from CDC25A, thereby playing a key role in cell cycle regulation. Deubiquitination of CDC25A prevents its degradation by the proteasome during the G1/S and G2/M phases of the cell cycle and is required for cell-cycle progression. Has transforming capabilities on cell lines. May also function in cell apoptosis.

Genbezeichner und Symbole assoziert mit USP17L2

  • ubiquitin specific peptidase 17-like family member 2 (USP17L2) Antikörper
  • ubiquitin carboxyl-terminal hydrolase 17 (LOC695235) Antikörper
  • DUB-3 Antikörper
  • DUB3 Antikörper
  • USP17 Antikörper

Bezeichner auf Proteinebene für USP17L2

deubiquitinating enzyme 17-like protein 2 , deubiquitinating enzyme 3 , deubiquitinating protein 3 , ubiquitin carboxyl-terminal hydrolase 17 , ubiquitin carboxyl-terminal hydrolase 17-like protein 2 , ubiquitin specific peptidase 17-like 2 , ubiquitin thioesterase 17-like protein 2 , ubiquitin thiolesterase 17-like protein 2 , ubiquitin-specific-processing protease 17-like protein 2

GENE ID SPEZIES
377630 Homo sapiens
695235 Macaca mulatta
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