anti-Ubiquitin Specific Peptidase 12 (USP12) Antikörper

Deubiquitinating enzyme. Zusätzlich bieten wir Ihnen USP12 Proteine (9) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
USP12 219333 O75317
USP12 360763  
USP12 22217 Q9D9M2
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Top anti-USP12 Antikörper auf antikoerper-online.de

Showing 10 out of 88 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-USP12 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Placenta 100 μL 2 bis 3 Tage
$319.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit  Target Name: Usp12  Sample Tissue: Mouse Stomach lysates  Antibody Dilution: 1.0 µg/mL 100 μL 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, WB USP12 Antibody (Center) western blot analysis in A375 cell line lysates (35 µg/lane). This demonstrates the USP12 antibody detected the USP12 protein (arrow). USP12 Antibody (Center) western blot analysis in mouse bladder tissue lysates (35 µg/lane). This demonstrates the USP12 antibody detected the USP12 protein (arrow). 0.4 mL 6 bis 8 Tage
$484.00
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL 6 bis 8 Tage
$484.00
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL 6 bis 8 Tage
$484.00
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$581.17
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis USP12 using K562 whole cell lysates 100 μL 11 bis 12 Tage
$390.77
Details
Human Maus Unkonjugiert WB 100 μL 11 bis 14 Tage
$522.50
Details
Maus Kaninchen Unkonjugiert WB Western blot analysis in mouse bladder tissue lysates (35ug/lane). Western blot analysis in A375 cell line lysates (35ug/lane). 400 μL 2 bis 3 Tage
$515.63
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$551.83
Details

Weitere Antikörper gegen USP12 Interaktionspartner

Human Ubiquitin Specific Peptidase 12 (USP12) Interaktionspartner

  1. WDR20 plays a crucial role in as a "targeting subunit" that modulates CRM1-dependent shuttling of the USP12/UAF1/WDR20 complex between the plasma membrane, cytoplasm and nucleus.

  2. USP12 deubiquitinates MDM2 and AR, which in turn controls the levels of the TP53 tumour suppressor and AR oncogene in prostate cancer.

  3. Findings indicate that deubiquitinase Usp12 (Usp12) overexpression accelerates autophagic flux and induces an approximately sixfold increase in autophagic structures as determined by ultrastructural analyses.

  4. Our results highlight the interfaces essential for regulation of USP12 activity and show a conserved second binding of UAF1 which could be important for regulatory functions independent of USP12 activity.

  5. UAF1 and WDR20 interact with USP12 at two distinct sites far from its catalytic center, allosterically activating the enzyme.

  6. Usp12 deubiquitylates and prevents lysosomal degradation of LAT and Trat1 to maintain the proximal TCR complex for the duration of signaling.

  7. Results suggest role for USP46/USP12 in Epstein-Barr virus induced growth transformation.

  8. Usp12 directly deubiquitinates and stabilises the Akt phosphatases PHLPP and PHLPPL resulting in decreased levels of active pAkt.

  9. Coimmunoprecipitation experiments indicated that human papillomavirus type 31 E1 assembles into a ternary complex with UAF1 and any one of these three USPs: USP1, USP12 and USP46.

  10. our results reveal WDR48 and USP12 as novel PHLPP1 regulators and potential suppressors of tumor cell survival

  11. Usp12 acts in a pro-proliferative manner by stabilizing AR and enhancing its cellular function.

  12. The ubiquitin-specific protease 12 (USP12) is a negative regulator of notch signaling acting on notch receptor trafficking toward degradation.

  13. WDR20 serves as a stimulatory subunit for preserving and regulating the activity of the subset of the UAF1 x USP12 complexes

  14. two novel multisubunit deubiquitinating enzyme complexes containing USP12 and USP46, respectively. Both complexes contain the UAF1 protein as a bona fide subunit. Interestingly, UAF1

Mouse (Murine) Ubiquitin Specific Peptidase 12 (USP12) Interaktionspartner

  1. Mechanistic analysis suggest that USP12 may be required for the activation of NFkappaB pathway as knockdown of USP12 reduced the inhibitory phosphorylation of IkappaBalpha, a well characterized inhibitor of NFkappaB nuclear translocation.

  2. Product has deubiquitinating enzyme activity and sequence analysis showed 98.3% amino acid identity with human UBH1.

Xenopus laevis Ubiquitin Specific Peptidase 12 (USP12) Interaktionspartner

  1. we identified USP12 and USP46 as histone H2A and H2B deubiquitinases that regulate Xenopus development

USP12 Antigen-Profil

Protein Überblick

Deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with wdr48 to have a high activity (By similarity).

Genbezeichner und Symbole assoziert mit USP12

  • ubiquitin specific peptidase 12 (USP12) Antikörper
  • ubiquitin specific peptidase 12 (usp12) Antikörper
  • ubiquitin specific peptidase 12 (Usp12) Antikörper
  • ubiquitin specific peptidase 12a (usp12a) Antikörper
  • ubiquitin specific peptidase 12 L homeolog (usp12.L) Antikörper
  • sb:eu882 Antikörper
  • ubh1 Antikörper
  • usp12 Antikörper
  • usp12l1 Antikörper
  • USP12P1 Antikörper
  • wu:fi09d12 Antikörper

Bezeichner auf Proteinebene für USP12

deubiquitinating enzyme 12 , ubiquitin carboxyl-terminal hydrolase 12 , ubiquitin specific protease 12 like 1 , ubiquitin thioesterase 12 , ubiquitin thiolesterase 12 , ubiquitin-hydrolyzing enzyme 1 , ubiquitin-specific-processing protease 12 , Deubiquitinating enzyme 12 , Ubiquitin thioesterase 12 , Ubiquitin-specific-processing protease 12 , ubiquitin specific protease 12 , ubiquitin specific peptidase 12 pseudogene 1 , ubiquitin-specific protease 12-like 1 , deubiquitinating enzyme 12A , ubiquitin carboxyl-terminal hydrolase 12A , ubiquitin specific peptidase 12 , ubiquitin thioesterase 12A , ubiquitin thiolesterase 12A , ubiquitin-specific-processing protease 12A , ubiquitin hydrolyzing enzyme 1 , Deubiquitinating enzyme 12-A , Ubiquitin thioesterase 12-A , Ubiquitin-specific-processing protease 12-A , ubiquitin carboxyl-terminal hydrolase 12-A , ubiquitin thiolesterase 12-A

GENE ID SPEZIES
219333 Homo sapiens
100194904 Salmo salar
360763 Rattus norvegicus
428078 Gallus gallus
486033 Canis lupus familiaris
525655 Bos taurus
565736 Danio rerio
735835 Pan troglodytes
100511469 Sus scrofa
22217 Mus musculus
734447 Xenopus laevis
100730392 Cavia porcellus
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