anti-Ubiquitin Specific Peptidase 1 (USP1) Antikörper

USP1 encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. Zusätzlich bieten wir Ihnen USP1 Proteine (8) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
USP1 7398 O94782
USP1 230484 Q8BJQ2
USP1 313387 Q569C3
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Top anti-USP1 Antikörper auf antikoerper-online.de

Showing 10 out of 104 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-USP1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human brain WB Suggested Anti-USP1 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: Human brain 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of USP1 expression in HEK293T (A), NIH3T3 (B), H9C2 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and human liver tissue labeled with Anti-USP-1 Polyclonal Antibody, Unconjugated (ABIN675578) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and human glioma tissue labeled with Anti-USP-1 Polyclonal Antibody, Unconjugated (ABIN675578) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$306.90
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$335.00
Details
Human Kaninchen Unkonjugiert IP 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: USP1 Antibody [ABIN2577927] - FFPE section of human thyroid carcinoma. Affinity purified rabbit anti-USP1 used at a dilution of 1:250. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Hund Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert WB USP1 Antibody (C-term)  western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the USP1 antibody detected the USP1 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-USP1 Pab (ABIN388876) in HepG2 cell line lysate (35 µg/lane). USP1(arrow) was detected using the purified polyclonal antibody (1:60 dilution) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details

Am meisten referenzierte anti-USP1 Antikörper

  1. Human Polyclonal USP1 Primary Antibody für IP - ABIN257791 : Lee, Yang, Cohn, Sikdar, DAndrea, Myung: Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1. in The Journal of biological chemistry 2010 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal USP1 Primary Antibody für IHC, IHC (p) - ABIN257792 : Murai, Yang, Dejsuphong, Hirota, Takeda, DAndrea: The USP1/UAF1 complex promotes double-strand break repair through homologous recombination. in Molecular and cellular biology 2011 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal USP1 Primary Antibody für IHC, IHC (p) - ABIN4364533 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

Weitere Antikörper gegen USP1 Interaktionspartner

Human Ubiquitin Specific Peptidase 1 (USP1) Interaktionspartner

  1. Our preclinical studies provide the framework for clinical evaluation of USP1 inhibitors, alone or in combination, as a potential novel multiple myeloma therapy.

  2. There is evidence that USP1/WDR48 (zeige WDR48 Antikörper) complex promotes cancer stem cell conservation and regulation of DNA damage repair. [REVIEW]

  3. These results outline a novel mechanism for the control of TBK1 (zeige TBK1 Antikörper) activity and suggest USP1-UAF1 (zeige WDR48 Antikörper) complex as a potential target for the prevention of viral diseases.

  4. USP1 is a key senescence regulator controlling genomic integrity.

  5. High USP1 expression is associated with glioma.

  6. USP1-UAF1 (zeige WDR48 Antikörper) complex promotes homologous recombination repair via multiple mechanisms: through FANCD2 (zeige FANCD2 Antikörper) deubiquitination, as well as by interacting with RAD51AP1 (zeige RAD51AP1 Antikörper).

  7. The results suggest that silencing USP1 inhibits cell proliferation and invasion in U2OS cells. Therefore, USP1 may provide a novel therapeutic target for the treatment of osteosarcoma.

  8. Translational regulation of the mRNA encoding USP1 is involved in the DNA damage response as a determinant of cisplatin resistance.

  9. Ubiquitination-specific proteases 1 (USP1)-mediated protein stabilization promotes glioblastoma (GBM) stem-like cells maintenance and treatment resistance, thereby providing a rationale for USP1 inhibition as a potential therapeutic approach against GBM.

  10. analysis of the function and regulation of the USP1-UAF1 (zeige WDR48 Antikörper) complex

Mouse (Murine) Ubiquitin Specific Peptidase 1 (USP1) Interaktionspartner

  1. our results strongly suggest that Usp1 is involved in the regulation of centrosome duplication, at least in part via ID1 (zeige ID1 Antikörper), and Usp1 may exert its oncogenic activity, partially through inducing centrosome abnormality.

  2. Data suggest Usp1 down-regulation by autocleavage is critical for Usp1 to exert role in DNA interstrand crosslink repair; Usp1 role is de-ubiquitination of Fancd2 (Fanconi anemia complementation group D2 (zeige FANCD2 Antikörper)) and Pcna (proliferating cell nuclear antigen (zeige PCNA Antikörper)).

  3. Homozygous Uaf1 (zeige WDR48 Antikörper)(-/-) embryos died at embryonic day 7.5 (E7.5). These mutant embryos were small and developmentally retarded.

  4. Autocleaved Usp1 remains a deubiquitylase because its fragments remain associated with Uaf1 (zeige WDR48 Antikörper), an enhancer of Usp1 activity, until the C-terminal fragment is selectively destroyed by the Arg/N-end rule pathway.

  5. Bone marrow from Fancd2 (zeige FANCD2 Antikörper)-/- mice and Usp1-/- mice exhibited marked hematopoietic defects.

  6. mouse Usp1 functions downstream in the Fanconi anemia (zeige PALB2 Antikörper) pathway, and its deubiquitination is required for Fancd2 (zeige FANCD2 Antikörper) nuclear foci assembly

USP1 Antigen-Profil

Protein Überblick

This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized.

Genbezeichner und Symbole assoziert mit USP1

  • ubiquitin specific peptidase 1 (USP1) Antikörper
  • ubiquitin specific peptidase 1 S homeolog (usp1.S) Antikörper
  • ubiquitin specific peptidase 1 (Usp1) Antikörper
  • UBP Antikörper
  • usp1-a Antikörper

Bezeichner auf Proteinebene für USP1

ubiquitin carboxyl-terminal hydrolase 1 , ubiquitin specific protease 1 , ubiquitin specific peptidase 1 , ubiquitin carboxyl-terminal hydrolase 1-like , deubiquitinating enzyme 1 , hUBP , ubiquitin carboxyl terminal hydrolase 1 , ubiquitin specific processing protease 1 , ubiquitin thioesterase 1 , ubiquitin thiolesterase 1 , ubiquitin-specific-processing protease 1 , ubiquitin specific peptdiase 1

GENE ID SPEZIES
100070397 Equus caballus
447465 Xenopus laevis
456901 Pan troglodytes
695157 Macaca mulatta
100443075 Pongo abelii
7398 Homo sapiens
230484 Mus musculus
313387 Rattus norvegicus
424685 Gallus gallus
479549 Canis lupus familiaris
100523071 Sus scrofa
516328 Bos taurus
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