anti-Ubiquitin Protein Ligase E3C (UBE3C) Antikörper

E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Zusätzlich bieten wir Ihnen UBE3C Proteine (4) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
UBE3C 362294  
UBE3C 100763 Q80U95
UBE3C 9690 Q15386
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Top anti-UBE3C Antikörper auf antikoerper-online.de

Showing 10 out of 41 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB Western blot analysis of UBE3C expression in HeLa (A), HepG2 (B), THP1 (C) whole cell lysates. 200 μL 13 bis 14 Tage
$487.50
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host:  Rabbit  Target Name:  UBE3C  Sample Type:  THP-1 whole cell lysates  Antibody Dilution:  1.0ug/ml 100 μL 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert ELISA, WB Western Blot (WB) analysis of specific cells using UBE3C Polyclonal Antibody. 100 μL Verfügbar
$363.46
Details
Human Kaninchen Unkonjugiert IF/ICC, IHC, WB Western blot analysis of extracts of various cell lines, using UBE3C antibody (ABIN5973842) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded human breast cancer using UBE3C Antibody (ABIN5973842) at dilution of 1/100 (40x lens). 100 μL 11 bis 16 Tage
$426.40
Details
Human Kaninchen Unkonjugiert IF, IHC, WB Western blot analysis of extracts of various cell lines, using UBE3C antibody. Immunohistochemistry of paraffin-embedded human breast cancer using UBE3C Antibody. 200 μL 12 bis 14 Tage
$438.90
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL 11 bis 12 Tage
$305.71
Details
Human Maus Unkonjugiert WB Western Blot analysis of UBE3C expression in transfected 293T cell line by UBE3C MaxPab polyclonal antibody.Lane 1: UBE3C transfected lysate(44.44 KDa).Lane 2: Non-transfected lysate. 50 μL 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of various cell lines, using UBE3C antibody. Immunofluorescence analysis of U2OS cell using UBE3C antibody. Blue: DAPI for nuclear staining. 100 μL 11 bis 13 Tage
$366.77
Details
Human Kaninchen Unkonjugiert WB   100 μL 11 bis 14 Tage
$375.83
Details
Human Kaninchen Unkonjugiert WB Western Blot analysis of UBE3C expression in transfected 293T cell line by UBE3C MaxPab polyclonal antibody.Lane 1: UBE3C transfected lysate(45.80 KDa).Lane 2: Non-transfected lysate. 100 μg 11 bis 12 Tage
$425.71
Details

Am meisten referenzierte anti-UBE3C Antikörper

  1. Human Polyclonal UBE3C Primary Antibody für IF, IHC - ABIN6149838 : Wen, Wen, Li, Jin, Wang, Zhou, Chen: UBE3C promotes growth and metastasis of renal cell carcinoma via activating Wnt/β-catenin pathway. in PLoS ONE 2016 (PubMed)

  2. Human Polyclonal UBE3C Primary Antibody für ELISA, WB - ABIN564179 : Urso, Chen, Scrimgeour, Lee, Lee, Clarkson: Alterations in mRNA expression and protein products following spinal cord injury in humans. in The Journal of physiology 2007 (PubMed)

Weitere Antikörper gegen UBE3C Interaktionspartner

Mouse (Murine) Ubiquitin Protein Ligase E3C (UBE3C) Interaktionspartner

  1. Usp14 and Ube3c cycle together on and off proteasomes, and the presence of ubiquitinated substrates promotes their association. This mechanism enables proteasome activity to adapt to the supply of substrates.

Human Ubiquitin Protein Ligase E3C (UBE3C) Interaktionspartner

  1. miR-542-3p functioned as a tumor suppressor gene in regulating the epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma via targeting UBE3C.

  2. Usp14 and Ube3c cycle together on and off proteasomes, and the presence of ubiquitinated substrates promotes their association. This mechanism enables proteasome activity to adapt to the supply of substrates.

  3. UBE3C promotes melanoma progression, possibly by inducing epithelial-mesenchymal transition in melanoma cells

  4. Ectopic overexpression of UBE4A, but not UBE3C, in cells was downregulated in vitro migration and invasion in these cells. Cumulatively, our data reveals a novel post-translational regulatory mechanism of regulating ILEI1 expression, a protein required for metastatic progression in prostate cancer cells

  5. data reveal that high UBE3C expression contributes to glioma progression by ubiquitination and degradation of ANXA7, and thus presents a novel and promising target for glioma therapy.

  6. these observations suggest that UBE3C plays an important role in RCC development and progression, and UBE3C may be a novel target for prevention and treatment of ccRCC.

  7. UBE3C is a mutant candidate oncogene involved in tumor development and progression of hepatocellular carcinoma.

  8. knockdown renders cells more susceptible to the Hsp90 inhibitor 17-AAG, suggesting that UBE3C protects against the harmful accumulation of protein fragments arising from incompletely degraded proteasome substrates.

  9. Our findings provide evidence that variations in UBE3C are potent genetic markers of nasal polyps development in Korean asthmatics.

  10. negatively regulates type I interferon through ubiquitination of the transcription factors

  11. gene polymorphism is associated with the risk of Aspirin-intolerant asthma

  12. TIP120B is a specific substrate of KIAA10; both are highly expressed in human skeletal muscle, suggesting that KIAA10 may regulate TIP120B homeostasis specifically in this tissue.

UBE3C Antigen-Profil

Protein Überblick

E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.

Genbezeichner und Symbole assoziert mit UBE3C

  • ubiquitin protein ligase E3C (UBE3C) Antikörper
  • ubiquitin protein ligase E3C (Ube3c) Antikörper
  • ubiquitin protein ligase E3C (ube3c) Antikörper
  • ubiquitin protein ligase E3C S homeolog (ube3c.S) Antikörper
  • AI853514 Antikörper
  • HECTH2 Antikörper
  • kiaa0010 Antikörper
  • MGC146390 Antikörper
  • mKIAA0010 Antikörper
  • RGD1559986 Antikörper
  • UBE3C Antikörper
  • zgc:63649 Antikörper

Bezeichner auf Proteinebene für UBE3C

ubiquitin-protein ligase E3C , ubiquitin protein ligase E3C , ubiquitin-protein isopeptide ligase (E3) , ubiquitin-protein ligase E3C-like

GENE ID SPEZIES
508513 Bos taurus
482822 Canis lupus familiaris
719956 Macaca mulatta
472637 Pan troglodytes
362294 Rattus norvegicus
393445 Danio rerio
100763 Mus musculus
420447 Gallus gallus
9690 Homo sapiens
380493 Xenopus laevis
779973 Xenopus (Silurana) tropicalis
100016776 Monodelphis domestica
100228118 Taeniopygia guttata
100475169 Ailuropoda melanoleuca
100547787 Meleagris gallopavo
100723450 Cavia porcellus
101925366 Macaca fascicularis
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