anti-Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4) Antikörper

The protein encoded by UBR4 is an E3 ubiquitin-protein ligase that interacts with the retinoblastoma-associated protein in the nucleus and with calcium-bound calmodulin in the cytoplasm. Zusätzlich bieten wir Ihnen UBR4 Kits (27) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
UBR4 23352 Q5T4S7
UBR4 69116 A2AN08
UBR4 313658 Q2TL32
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Top anti-UBR4 Antikörper auf antikoerper-online.de

Showing 10 out of 32 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert ELISA Immunohistochemistry (5μg/ml) staining of paraffin embedded Human Spleen. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry-Paraffin: UBR4 Antibody  - Staining of human prostate shows strong cytoplasmic positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: UBR4 Antibody [NBP1-28724] - FFPE section of human prostate carcinoma. Antibody used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Fledermaus Ziege Unkonjugiert ELISA, IHC, IHC (p) Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$639.83
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, WB Western Blot: UBR4 Antibody [NBP1-28730] - Detection of Human p600 on HeLa whole cell lysate using NBP28730. p600 was also immunoprecipitated by rabbit anti-p600 antibodies NBP1-28683 and NBP1-28724. Immunohistochemistry-Paraffin: UBR4 Antibody [NBP1-28730] - section of human prostate carcinoma. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Ziege Unkonjugiert ELISA, IHC   0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Kaninchen Unkonjugiert ICC, IHC, WB Figure. Western Blot; Sample: Recombinant protein. Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$386.00
Details
Human Maus Unkonjugiert ELISA, IF, WB Immunofluorescence of to RBAF600 on HeLa cell . Detection limit for recombinant GST tagged RBAF600 is approximately 0.1 ng/mL as a capture antibody. 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$461.00
Details
Human Maus Unkonjugiert IF, ELISA, WB Immunofluorescence of monoclonal antibody to RBAF600 on HeLa cell. [antibody concentration 10 ug/ml] Detection limit for recombinant GST tagged RBAF600 is approximately 0.1ng/ml as a capture antibody. 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details

UBR4 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-UBR4 Antikörper

  1. Human Polyclonal UBR4 Primary Antibody für ICC, IF - ABIN440546 : Corteggio, Di Geronimo, Roperto, Roperto, Borzacchiello: Bovine papillomavirus E7 oncoprotein binds to p600 in naturally occurring equine sarcoids. in The Journal of general virology 2011 (PubMed)

  2. Human Polyclonal UBR4 Primary Antibody für ELISA, IHC - ABIN4364019 : Lennerz, Fatho, Gentilini, Frye, Lifke, Ferel, Wölfel, Huber, Wölfel: The response of autologous T cells to a human melanoma is dominated by mutated neoantigens. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)

  3. Human Polyclonal UBR4 Primary Antibody für IHC, IHC (p) - ABIN4364020 : Ling, Beaulé, Chiang, Tian, Figeys, Cheng: Time-of-day- and light-dependent expression of ubiquitin protein ligase E3 component N-recognin 4 (UBR4) in the suprachiasmatic nucleus circadian clock. in PLoS ONE 2014 (PubMed)

Weitere Antikörper gegen UBR4 Interaktionspartner

Human Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4) Interaktionspartner

  1. Ubiquitin ligase Ubr4 is a key component of the podocin interactome purified from podocytes. Ubiquitylation of one podocin site, K301, do not only target podocin for proteasomal degradation, but may also affect stability and disassembly of the multimeric complex.

  2. Results showed KCMF1 (zeige KCMF1 Antikörper) C-terminus binds directly to RAD6, whereas N-terminal domains interact with UBR4 and point mutations found in X-linked intellectual disability (XLID) patients specifically lose the interaction with KCMF1 (zeige KCMF1 Antikörper) and UBR4.

  3. This review summarizes the central nervous system functions of p600 (zeige IL13 Antikörper) and proposes new perspectives on its biological complexity in neuronal physiology and neurological diseases.

  4. Although UBR4 is not an ion channel gene, the potential for disrupted Ca(2+) control within neuronal cells highlights its potential for a role in this form of episodic ataxia.

  5. Dengue virus co-opts UBR4 to degrade STAT2 (zeige STAT2 Antikörper) and antagonize type I interferon (zeige IFNA Antikörper) signaling.

  6. Human papillomavirus E7 oncoprotein associates with p600 (zeige IL13 Antikörper); interaction strongly contributes to cellular transformation independent of ability of E7 to bind pRB (zeige RB1 Antikörper).

  7. Results identify and characterize p600, a unique 600-kDa retinoblastoma protein- and calmodulin-binding protein.

Mouse (Murine) Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4) Interaktionspartner

  1. Ubiquitin ligase Ubr4 is a key component of the podocin interactome purified from cultured podocytes and native glomeruli. Ubiquitylomic analysis of mouse glomeruli revealed that podocin is ubiquitylated at two lysine residues. Ubiquitylation of one podocin site, K301, do not only target podocin for proteasomal degradation, but may also affect stability and disassembly of the multimeric complex.

  2. This study is the first to identify a novel E3 ubiquitin ligase (zeige MUL1 Antikörper) component, UBR4, in the murine SCN (zeige SRI Antikörper) and to implicate the N-end rule degradation pathway as a potential player in regulating core clock mechanisms and photic entrainment.

  3. UBR4-deficient mice die during embryogenesis and exhibit pleiotropic abnormalities, including impaired vascular development in the yolk sac (zeige ADCY10 Antikörper).

  4. Found murine p600 (formally called RBAF600) copurified with the E7 oncoprotein in C127 cells. This interaction was found to correlate with the ability of E7 to increase transformation.

  5. This study identified protein 600 (p600) as a novel microtubule-associated protein (zeige SPAG5 Antikörper) (MAP) developmentally regulated in neurons. p600 exhibits the unique feature to interact with the endoplasmic reticulum (ER).

  6. Member of UBR box protein family, termed Ubr4. Binds to destabilizing N-terminal residues of N-end rule substrates. Participates in degradation of N-end rule substrates.

UBR4 Antigen-Profil

Protein Überblick

The protein encoded by this gene is an E3 ubiquitin-protein ligase that interacts with the retinoblastoma-associated protein in the nucleus and with calcium-bound calmodulin in the cytoplasm. The encoded protein appears to be a cytoskeletal component in the cytoplasm and part of the chromatin scaffold in the nucleus. In addition, this protein is a target of the human papillomavirus type 16 E7 oncoprotein.

Genbezeichner und Symbole assoziert mit UBR4

  • ubiquitin protein ligase E3 component n-recognin 4 (UBR4) Antikörper
  • ubiquitin protein ligase E3 component n-recognin 4 (Ubr4) Antikörper
  • E3 ubiquitin-protein ligase UBR4 (LOC100511934) Antikörper
  • 1810009A16Rik Antikörper
  • A930005E13Rik Antikörper
  • D930005K06Rik Antikörper
  • Gm1032 Antikörper
  • Gm1666 Antikörper
  • mKIAA0462 Antikörper
  • N28143 Antikörper
  • p600 Antikörper
  • Rbaf600 Antikörper
  • Zubr1 Antikörper

Bezeichner auf Proteinebene für UBR4

retinoblastoma-associated factor 600 , zinc finger, UBR1 type 1 , E3 ubiquitin-protein ligase UBR4 , N-recognin-4 , retinoblastoma-associated factor 600-like protein , retinoblastoma-associated factor of 600 kDa , zinc finger UBR1-type protein 1 , ZUBR1

GENE ID SPEZIES
456576 Pan troglodytes
23352 Homo sapiens
478211 Canis lupus familiaris
69116 Mus musculus
313658 Rattus norvegicus
100511934 Sus scrofa
419469 Gallus gallus
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