anti-Twisted Gastrulation Homolog 1 (Drosophila) (TWSG1) Antikörper

May be involved in dorsoventral axis formation. Zusätzlich bieten wir Ihnen TWSG1 Proteine (19) und TWSG1 Kits (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TWSG1 65960 Q9EP52
TWSG1 57045 Q9GZX9
TWSG1 363294  
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Top anti-TWSG1 Antikörper auf antikoerper-online.de

Showing 10 out of 35 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ICC, IHC, WB Figure. Western Blot; Sample: Recombinant protein. Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg 13 bis 16 Tage
$350.00
Details
Human Maus Unkonjugiert ELISA, IHC, IHC (p), WB Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-TSG / TWSG1 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 50 μg 11 bis 14 Tage
$561.00
Details
Human Maus Unkonjugiert ELISA, WB TWSG1 monoclonal antibody (M07), clone 2F3. Western Blot analysis of TWSG1 expression in human kidney. Detection limit for recombinant GST tagged TWSG1 is 0.3 ng/ml as a capture antibody. 100 μg 11 bis 12 Tage
$440.00
Details
Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged TWSG1 is approximately 0.1ng/ml as a capture antibody. Western Blot analysis of TWSG1 expression in transfected 293T cell line by TWSG1 monoclonal antibody (M01), clone 6E6.Lane 1: TWSG1 transfected lysate(25 KDa).Lane 2: Non-transfected lysate. 100 μg 11 bis 12 Tage
$440.00
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL 11 bis 12 Tage
$305.71
Details
Human Kaninchen Unkonjugiert IF/ICC, IHC, IP, WB Western blot analysis of the recombinant protein. IHC-P analysis of Human Tissue, with DAB staining. 100 μg 31 bis 36 Tage
$440.62
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB   100 μg 13 bis 16 Tage
$407.69
Details
Human Kaninchen Alexa Fluor 350 IF (p)   100 μL 14 bis 21 Tage
$416.90
Details
Human Kaninchen FITC IF (p)   100 μL 14 bis 21 Tage
$416.90
Details
Human Kaninchen Alexa Fluor 647 IF (p)   100 μL 14 bis 21 Tage
$416.90
Details

Am meisten referenzierte anti-TWSG1 Antikörper

  1. Human Monoclonal TWSG1 Primary Antibody für ELISA, WB - ABIN528066 : Koutlas, Forsman, Kyrkanides, Oetting, Petryk: Autosomal dominant mesomandibular fibro-osseous dysplasia: a self-resolving inherited fibro-osseous lesion of the jaws. in Frontiers in physiology 2012 (PubMed)

  2. Human Polyclonal TWSG1 Primary Antibody für ICC, IF - ABIN4363081 : Larman, Karolak, Adams, Oxburgh: Chordin-like 1 and twisted gastrulation 1 regulate BMP signaling following kidney injury. in Journal of the American Society of Nephrology : JASN 2009 (PubMed)

Weitere Antikörper gegen TWSG1 Interaktionspartner

Cow (Bovine) Twisted Gastrulation Homolog 1 (Drosophila) (TWSG1) Interaktionspartner

  1. TSG is an important modulator of BMP-regulated induced collagen II and X expression and cartilage development and chondrocyte differentiation

Mouse (Murine) Twisted Gastrulation Homolog 1 (Drosophila) (TWSG1) Interaktionspartner

  1. Our results show that BMP binding is required for TWSG1-mediated inhibition of osteoclast formation and function, and validate the critical functional regions within the TWSG1 protein for these interactions

  2. The goal of this study was to examine whether mice carrying a mutation in a gene encoding Twsg1, which is associated with a low penetrance of holoprosencephaly, are sensitized to retinoic acid teratogenesis.

  3. BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization.

  4. Data show that Bmp4, Bmp7, Gremlin and Twisted gastrulation (Twsg1) are all expressed in the thymus and expression was clearly different for each gene investigated.

  5. suggesting that Twsg1 expression in B cells serves to interpret BMP signals on a per-cell basis

  6. These results demonstrate that phenotypic variability in Twsg1-/- mice is associated with differential expression of certain developmentally regulated genes, and that craniofacial defects can be partially rescued by reduced p53 levels.

  7. TWSG1 overexpression inhibits RANKL-induced osteoclast differentiation

  8. TWSG1 appears to be the main regulator of BMP present in CP.

  9. Cv2 enhances pro-BMP activity of Tsg.

  10. The developmentally regulated expression of Twisted gastrulation reveals a role for bone morphogenetic proteins in the control of T cell development.

  11. acts as both a BMP-4 agonist in skeletogenesis and a BMP-4 antagonist in T-cell development

  12. Tsg-/-;Bmp4+/- compound mutants die at birth and display holoprosencephaly, first branchial arch and eye defects

  13. results suggest that twisted gastrulation and chordin are involved in osteoblast differentiation and mineralization by regulating BMP signaling

  14. Tsg overexpression inhibits BMP action in stromal and preosteoblastic cells and, accordingly, arrests their differentiation toward the osteoblastic pathway

  15. TSG is an important modulator of BMP-regulated induced collagen II and X expression and cartilage development and chondrocyte differentiation

  16. endogenous Tsg is required for normal BMP activity in osteoblastic cells in vitro, but it plays a minor role in the regulation of adult bone homeostasis in vivo

  17. The context-dependent functional relationship between Tsg and Cv2 during mouse development, is presented.

  18. Development of the vertebral morphogenetic field is reported in the interactions of CV-2 and Twg.

  19. Twsg1 limits apoptosis in the distal region of the mandibular arch in mice.

  20. Twsg1 interferes with BMP-mediated hepcidin expression and may act with GDF15 to dysregulate iron homeostasis

Human Twisted Gastrulation Homolog 1 (Drosophila) (TWSG1) Interaktionspartner

  1. Internal cleavage and synergy with TWSG1 enhance BMP-4 inhibition by BMPER.

  2. Findings indicate that twisted gastrulation homolog 1 (TWSG1) maybe serves as a tumor suppressor gene in gastric cancer and potential biomarker or therapeutic target for the diagnosis and treatment of gastric cancer.

  3. Tsg functions as a BMP-agonist by inducing conformational change in chordin making it more susceptible to tolloid cleavage and as a BMP-antagonist either independently or via a chordin-mediated mechanism.

  4. Data suggest CHRD (chordin) cleavage by tolloid-like metalloproteinases is insufficient to regulate BMP(bone morphogenetic protein)/BMPR signaling; CHRD fragments and TSG (twisted gastrulation protein) contribute to inhibition of BMP/BMPR signaling.

  5. these results suggest that BMPER and Tsg maintain a fine-tuned equilibrium that controls BMP pathway activity and is necessary for vascular cell homeostasis.

  6. mutations in the twisted gastrulation homolog 1 gene are neither a common direct cause nor a frequent modifying factor for human holoprosencephaly pathologies

  7. Tsg functions as an agonist synergizing with TGF-beta to inhibit T-cell activation.

  8. interferes with BMP-mediated hepcidin expression and may act with GDF15 to dysregulate iron homeostasis in thalassemia syndromes.

Zebrafish Twisted Gastrulation Homolog 1 (Drosophila) (TWSG1) Interaktionspartner

  1. Data show that in endothelial cells, bone morphogenetic protein endothelial precursor-derived regulator (BMPER) and twisted gastrulation protein homolog 1 (TWSG1) are necessary for regular Notch signaling activity.

  2. Twisted gastrulation enhances BMP signaling through chordin dependent and independent mechanisms

  3. zebrafish Tsg1 promotes BMP signaling, and thus ventral cell fates, during DV axial patterning

TWSG1 Antigen-Profil

Protein Überblick

May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity).

Genbezeichner und Symbole assoziert mit TWSG1

  • twisted gastrulation BMP signaling modulator 1 (TWSG1) Antikörper
  • twisted gastrulation homolog 1 (Drosophila) (TWSG1) Antikörper
  • twisted gastrulation BMP signaling modulator 1 (Twsg1) Antikörper
  • twisted gastrulation BMP signaling modulator 1a (twsg1a) Antikörper
  • twisted gastrulation BMP signaling modulator 1 S homeolog (twsg1.S) Antikörper
  • twisted gastrulation BMP signaling modulator 1b (twsg1b) Antikörper
  • 1810013J15Rik Antikörper
  • 9030422N06Rik Antikörper
  • AW552143 Antikörper
  • D17Ertd403e Antikörper
  • DKFZp469J051 Antikörper
  • fi23f01 Antikörper
  • tsg Antikörper
  • tsg1 Antikörper
  • tsga Antikörper
  • tsgb Antikörper
  • Twg Antikörper
  • twsg Antikörper
  • twsg1 Antikörper
  • wu:fi23f01 Antikörper
  • ztsg1 Antikörper

Bezeichner auf Proteinebene für TWSG1

twisted gastrulation homolog 1 (Drosophila) , twisted gastrulation protein homolog 1 , twisted gastrulation homolog 1 , Twisted gastrulation protein homolog 1 , twisted gastrulation 1 , twisted gastrulation a , twisted gastrulation protein homolog 1-A , twisted gastrulation b , twisted gastrulation protein homolog 1-B

GENE ID SPEZIES
455294 Pan troglodytes
537290 Bos taurus
705804 Macaca mulatta
490546 Canis lupus familiaris
374024 Gallus gallus
100172557 Pongo abelii
65960 Mus musculus
57045 Homo sapiens
363294 Rattus norvegicus
84037 Danio rerio
399387 Xenopus laevis
259304 Danio rerio
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