anti-Tumor Necrosis Factor-Inducible Protein 6 (TNFAIP6) Antikörper

The protein encoded by TNFAIP6 is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. Zusätzlich bieten wir Ihnen Tumor Necrosis Factor-Inducible Protein 6 Kits (39) und Tumor Necrosis Factor-Inducible Protein 6 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TNFAIP6 84397  
TNFAIP6 21930 O08859
TNFAIP6 7130 P98066
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-Tumor Necrosis Factor-Inducible Protein 6 Antikörper auf antikoerper-online.de

Showing 10 out of 47 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL 2 bis 3 Tage
$319.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IP, IHC, WB Immunohistochemical analysis of TSG6 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of TSG6 expression in MCF7 (A), HCT15 (B), HeLa (C) whole cell lysates. 200 μL 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of TSG6 expression in rat brain extract ( Lane 1) and HELA whole cell lysates ( Lane 2). TSG6 at 31KD was detected using rabbit anti- TSG6 Antigen Affinity purified polyclonal antibody (Catalog #) at 0.5 µg/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). 100 μg 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from Jurkat/HeLa/HepG2 cells, using TSG6 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, WB ABIN6269034 staining Hela by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. Western blot analysis of TSG6 expression in HeLa cells.The lane on the left is treated with the antigen-specific peptide. 100 μL 11 bis 12 Tage
$390.77
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of mouse brain, using TNFAIP6 Antibody. Immunohistochemistry of paraffin-embedded human stomach using TNFAIP6 antibody. 200 μL 12 bis 14 Tage
$438.90
Details
Maus Kaninchen Unkonjugiert ICC, IHC, WB Figure. Western Blot; Sample: Recombinant TNFaIP6, Mouse. Figure.DAB staining on IHC-P. Samples: Mouse Tissue 100 μg 13 bis 16 Tage
$396.00
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB   100 μL Verfügbar
$363.46
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB 0.1 mg 6 bis 8 Tage
$434.50
Details
Human Huhn Unkonjugiert WB 0.05 mg 2 bis 3 Tage
$515.63
Details

Am meisten referenzierte anti-Tumor Necrosis Factor-Inducible Protein 6 Antikörper

  1. Human Polyclonal TNFAIP6 Primary Antibody für IHC, IHC (p) - ABIN4363082 : Eikrem, Strauss, Beisland, Scherer, Landolt, Flatberg, Leh, Beisvag, Skogstrand, Hjelle, Shresta, Marti: Development and confirmation of potential gene classifiers of human clear cell renal cell carcinoma using next-generation RNA sequencing. in Scandinavian journal of urology 2016 (PubMed)

Weitere Antikörper gegen Tumor Necrosis Factor-Inducible Protein 6 Interaktionspartner

Mouse (Murine) Tumor Necrosis Factor-Inducible Protein 6 (TNFAIP6) Interaktionspartner

  1. TSG-6 deficiency protects against airway hyperresponsiveness after ozone (in vivo) or short-fragment hyaluronan (sHA) (in vitro and in vivo) exposure. Moreover, TSG-6(-/-) tracheal ring non-responsiveness to sHA was reversed by exogenous TSG-6 addition.

  2. Loss of TSG6 expression is associated with Embryos failing to Initiate Midgut Rotation.

  3. TSG-6 up-regulation counteracts the progression of atherosclerosis. (Review)

  4. our results showed that the increase of oxidative stress, activation of the NLRP3 inflammasome and NF-kappaB signaling in SAP was substantially inhibited following administration of hMSCs or TSG-6, which was dependent on the presence of CD-44 receptors in acinar cells.

  5. TSG-6 protects hepatocytes from damage by enhancing autophagy influx and contributes to liver regeneration

  6. TSG6 functions by converting macrophages from a proinflammatory to an anti-inflammatory phenotype secondary to suppression of TLR4/NF-kappaB signaling and STAT1 and STAT3 activation.

  7. This study provided the first evidence of TSG-6 secreted by mesenchymal stem cells promoting corneal epithelial wound healing in diabetic mice through activating corneal epithelial stem/progenitor cells and accelerating M2 macrophage polarization

  8. This study shows that TSG-6 is expressed in the CNS, suggesting a role for TSG-6 in astrocyte activation and tissue repair.

  9. Data (including data from studies in knockout mice) suggest that TSG-6 is needed for release of hyaluronan rafts (leukocyte-adhesive rafts) from apical surface of tracheal mucosa into bronchoalveolar lavage fluid as heavy chain hyaluronan complexes.

  10. the well characterized hyaluronan-binding site in the TSG-6 Link module is not used for recognition during transfer of HCs onto HA.

  11. Thus, TSG6, HA, and IalphaI were crucial factors for the settlement and probably the subsequent differentiation of MSCs.

  12. BM-MSCs injected into mice with colitis do not localize to the intestine but instead form aggregates in the peritoneum where they produce immunoregulatory molecules, including TSG6, that reduce intestinal inflammation.

  13. This study demonstrated that following stimulation with TNF-alpha, MSCs modulate microglia activity through TSG-6.

  14. suggest that TSG-6 plays an important role in MSCs-mediated immunosuppressive effect on DC

  15. This study provides insight into what we believe to be a previously undescribed multifaceted role of mesenchymal stem cell-released TSG-6 in wound healing.

  16. TSG-6 is implicated in the experimental murine model of allergic pulmonary inflammation and is likely to contribute to the pathogenesis of asthma

  17. TSG-6 increases the accumulation of HA in the cell-associated matrix, partially by preventing its dissolution from the cell-associated matrix into the conditioned medium, but primarily by inducing HA synthesis

  18. analysis of irreversible heavy chain transfer to hyaluronan oligosaccharides by tumor necrosis factor-stimulated gene-6

  19. cells expressing CD44/TSG-6 failed to roll on hyaluronan, instead, they stuck and remained "tethered" to the substrate under fluid flow

  20. observations identify tumor necrosis factor-alpha-stimulated gene 6 as a target of prostaglandin action and show that its production in ovulatory follicles is associated with proper formation of the cumulus-derived extracellular matrix

Human Tumor Necrosis Factor-Inducible Protein 6 (TNFAIP6) Interaktionspartner

  1. TSG-6 is constitutively expressed in some tissues, which are either highly active or subject to challenges. The diversity of its functions depend on its binding to ligands such as glycosaminoglycans, immune regulators and growth factors that themselves interact with these linear polysaccharides. TSG-6 can directly affect matrix structure and modulate its interaction with the extracellular signaling molecules. [review]

  2. The expression levels of Fas, FasL, FADD, caspase-3 and caspase- 8 were significantly raised in the TSG-6 overexpressing hypertrophic scar fibroblasts.

  3. Findings indicate that TSG6 is a novel regulator of keloid fibrogenesis.

  4. TSG-6 secreted by human adipose tissue-derived mesenchymal stem cells (hAT-MSCs) protects pancreatic acinar cells in severe acute pancreatitis model mice via the inhibition of endoplasmic reticulum stress, as well as inflammatory responses. This study has revealed a new area for ER stress-targeted therapy in SAP patients

  5. the results suggest that MSCs inhibit inflammatory neovascularization in the cornea by suppressing pro-angiogenic monocyte/macrophage recruitment in a TSG-6-dependent manner.

  6. We demonstrated that hAT-MSC-secreted TSG-6 induced macrophages that infiltrated into the colon to switch to the M2 phenotype, thus regulating the expression of inflammatory cytokines and the alleviation of DSS-induced colitis symptoms in mice.

  7. TSG-6 up-regulation counteracts the progression of atherosclerosis. (Review)

  8. TSG-6 from MSCs attenuated severe burn-induced excessive inflammation via inhibiting activation of P38 and JNK signaling.

  9. TSG-6 secreted by human mesenchymal stem cells suppresses inflammatory reactions through p38 and ERK in the mitogen-activated protein kinase pathway

  10. This review will focus on the potential of mesenchymal stem/stromal cells for treatment of fibrotic diseases, with emphasis on the role of TSG-6 as a mediator of anti-inflammatory effects

  11. abnormally elevated in both the plasma and aortic wall of patients with abdominal aortic aneurysms

  12. Single nucleotide polymorphism in TNFAIP6 gene is associated with Systemic lupus erythematosus.

  13. TNFAIP6 expression is significantly upregulated in human masticatory mucosa during wound healing

  14. Data show that TNF-stimulated gene-6 (TSG-6) interacts with chemokines through their glycosaminoglycans (GAGs)-binding sites and inhibits their binding to GAGs and endothelial cell surfaces.

  15. The current study describes a novel mechanism linking the TSG-6 transfer of the newly described HC5 to the HA-dependent control of cell phenotype. The interaction of HC5 with cell surface HA was essential for TGFbeta1-dependent differentiation of fibroblasts to myofibroblasts, highlighting its importance as a novel potential therapeutic target.

  16. Data postulate that the molecular cross-linking enhanced by the multiple binding modes of the Link module might be critical for remodeling the ECM during inflammation/ovulation and might contribute to other functions of TSG-6.

  17. the well characterized hyaluronan-binding site in the TSG-6 Link module is not used for recognition during transfer of HCs onto HA.

  18. TSG-6 exhibited anti-inflammatory effects during the wound healing process and cicatrization and significantly diminished hypertrophic scar formation in a rabbit ear model

  19. results suggest that systemic administration of hASC or TSG-6 may be novel approaches to reverse CS-induced myelosuppression.

  20. TSG-6 activity in tissues, was examined.

Tumor Necrosis Factor-Inducible Protein 6 (TNFAIP6) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.

Genbezeichner und Symbole assoziert mit TNFAIP6

  • TNF alpha induced protein 6 (Tnfaip6) Antikörper
  • TNF alpha induced protein 6 (TNFAIP6) Antikörper
  • tumor necrosis factor alpha induced protein 6 (Tnfaip6) Antikörper
  • Tnfip6 Antikörper
  • TSG-6 Antikörper
  • TSG6 Antikörper

Bezeichner auf Proteinebene für TNFAIP6

tumor necrosis factor alpha induced protein 6 , tumor necrosis factor-inducible gene 6 protein , tumor necrosis factor-inducible protein 6 , TNF alpha-induced protein 6 , TNF-stimulated gene 6 protein , tumor necrosis factor alpha-induced protein 6 , tumor necrosis factor induced protein 6 , tumor necrosis factor, alpha-induced protein 6 , hyaluronate-binding protein , tumor necrosis factor alpha-inducible protein 6 , tumor necrosis factor-stimulated gene-6 protein , TSG-6 , hyaluronate-binding protein PS4 , secreted hyaluronate binding protein

GENE ID SPEZIES
84397 Rattus norvegicus
424315 Gallus gallus
21930 Mus musculus
7130 Homo sapiens
100009149 Oryctolagus cuniculus
Ausgewählte Anbieter für anti-Tumor Necrosis Factor-Inducible Protein 6 (TNFAIP6) Antikörper
Haben Sie etwas anderes gesucht?