Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Zusätzlich bieten wir Ihnen Tumor Necrosis Factor Receptor Superfamily, Member 11b Kits (91) und Tumor Necrosis Factor Receptor Superfamily, Member 11b Proteine (36) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 174 products:
Human Monoclonal TNFRSF11B Primary Antibody für CyTOF, FACS - ABIN252469
Kobayashi, Hashimoto, Miyamoto, Kanaoka, Miyazaki-Kawashita, Nakashima, Shibata, Kobayashi, Kato, Sakai: Force-induced osteoclast apoptosis in vivo is accompanied by elevation in transforming growth factor beta and osteoprotegerin expression. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001
Show all 26 Pubmed References
Cow (Bovine) Polyclonal TNFRSF11B Primary Antibody für IHC, ELISA - ABIN1582232
Fradet, Sorel, Bouazza, Goehrig, Dépalle, Bellahcène, Castronovo, Follet, Descotes, Aubin, Clézardin, Bonnelye: Dual function of ERR? in breast cancer and bone metastasis formation: implication of VEGF and osteoprotegerin. in Cancer research 2011
Show all 5 Pubmed References
Human Monoclonal TNFRSF11B Primary Antibody für ICC, FACS - ABIN969439
Golledge, Biros, Clancy, Cooper, Palmer, Norman: A single-nucleotide polymorphism in the gene encoding osteoprotegerin is associated with diastolic blood pressure in older men. in American journal of hypertension 2009
Show all 2 Pubmed References
Human Monoclonal TNFRSF11B Primary Antibody für IHC, ELISA - ABIN969440
Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ... in American journal of human genetics 2009
Show all 2 Pubmed References
Human Monoclonal TNFRSF11B Primary Antibody für ELISA, WB - ABIN2475981
Westheimer: Why nature chose phosphates. in Science (New York, N.Y.) 1987
Show all 3 Pubmed References
Human Monoclonal TNFRSF11B Primary Antibody für WB - ABIN2668734
Sood, Balasubramanian, Higham, Fernando, Harrison: Osteoprotegerin (OPG) and related proteins (RANK, RANKL and TRAIL) in thyroid disease. in World journal of surgery 2011
Progressive calcification of atherosclerotic plaques is accompanied by insignificant accumulation of calcitonin (zeige CALCA Antikörper) and osteoprotegerin, whereas the osteocalcin (zeige BGLAP Antikörper) expression significantly increased during calcification.
Elevated serum ferritin (zeige FTL Antikörper) concentrations and bone remodeling marker, osteoprotegerin, are independent predictors of hip fracture in postmenopausal women hospitalized for fragility fracture.
Results showed that colorectal liver metastasis tissues exhibited significantly reduced expression of osteoprotegerin compared to primary colorectal carcinomas and normal colorectal mucosa. This reduced expression was significantly associated with the extent of colorectal liver metastasis, including multiplicity of metastatic tumors, involvement of the bilateral hepatic lobes, and higher histological grade.
Data indicate that the RANKL (zeige TNFSF11 Antikörper)/RANK/OPG system is deregulated in post-menopausal women at high risk for breast cancer and in women with circulating tumor cells. Thus, serum levels of RANKL/OPG (zeige TNFSF11 Antikörper) are potentially indicative of predisposition and progression of breast cancer in humans.
High OPG expression is associated with triple negative breast cancer.
show for the first time that OPG improves risk stratification for cardiovascular events in a non-dialysis chronic kidney disease population
OPG has a role in cancer progression, especially breast cancer [review]
OPG rs2073618 polymorphism could be a possible genetic marker for the prediction of increased risk for carotid plaque burden as a measure of advanced subclinical atherosclerosis in T2DM subjects.
The compound with greatest potential is E05657 with high activity and low effective concentration in the HTS (zeige APCDD1 Antikörper) system. It increases the OPG/RANKL (zeige TNFSF11 Antikörper) ratio and OPG secretion, decreases the NFATc1 (zeige NFATC1 Antikörper) expression, and reduces osteoclastogenesis in vitro
OPG T950C polymorphism might be associated with an increased osteoporosis risk in the Chinese population
findings demonstrate that mTORC1 activation-stimulated RANKL (zeige TNFSF11 Antikörper) expression in B cells is sufficient to induce bone loss and osteoporosis. The study also established a link between mTORC1 and the RANKL/OPG (zeige TNFSF11 Antikörper) axis via negative regulation of beta-catenin (zeige CTNNB1 Antikörper).
RANK/RANKL (zeige TNFSF11 Antikörper) signaling is involved in the androgen deprivation therapy-induced acceleration of bone metastasis in castration-insensitive prostate cancer and is inhibited by osteoprotegerin to prevent bone metastasis.
endocortical resorption is driven by reduced OPG (zeige TNFSF11 Antikörper) rather than elevated RANKL (zeige TNFSF11 Antikörper) expression
Diabetes significantly increased OPG (zeige TNFSF11 Antikörper) and the OPG (zeige TNFSF11 Antikörper)/TRAIL ratio expression in the aorta, while dyslipidemia was the major determinant of the changes observed in the heart, where it significantly increased OPG (zeige TNFSF11 Antikörper) and reduced TRAIL expression, thus increasing cardiac OPG (zeige TNFSF11 Antikörper)/TRAIL ratio.
These discoveries strongly suggest that Heparan Sulfate plays an active role in regulating OPG-RANKL (zeige TNFSF11 Antikörper) interaction and osteoclastogenesis.
OPG (zeige TNFSF11 Antikörper) plays an important role in regulating bone marrow mesenchymal stem cells differentiation and bone marrow adipogenesis.
These data suggested that OPG (zeige TNFSF11 Antikörper) played an important role in maintaining the homeostasis of articular cartilage of femoral head.
Data show that p38alpha (zeige MAPK14 Antikörper) mitogen-activated protein kinase (zeige MAPK1 Antikörper) (MAPK (zeige MAPK1 Antikörper)) in paired related homeobox 1 (zeige PRRX1 Antikörper) protein (Prx1 (zeige PRDX1 Antikörper)+) bone marrow-derived mesenchymal stromal cells acts to preserve the bone by sustaining osteoprotegerin (OPG) production.
OPG (zeige TNFSF11 Antikörper) expression in chondrocyte increases bone mass in the proximal metaphysis of tibiae through negative regulation of osteoclast formation.
the generation of Rag2GFP+ regulatory T cells is unaltered in Tnfrsf11b(-/-) mice
The OPG (zeige TNFSF11 Antikörper) expression levels decreased while those of RANKL (zeige TNFSF11 Antikörper) and RUNX2 (zeige RUNX2 Antikörper) increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue.
Low-frequency vibration may promote the osteogenic differentiation capability of BMSC probably through regulating the OPG/RANKL (zeige TNFSF11 Antikörper) mRNA expression.
Regional variation of periosteal activity at the mandibular ramus is regulated by differential expression of osteoprotegerin.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
osteoclastogenesis inhibitory factor
, tumor necrosis factor receptor superfamily member 11B
, tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
, tumor necrosis factor receptor superfamily, member 11b
, tumor necrosis factor receptor superfamily member 11B-like