anti-Trophoblast Glycoprotein (TPBG) Antikörper

TPBG encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. Zusätzlich bieten wir Ihnen TPBG Proteine (11) und TPBG Kits (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TPBG 7162 Q13641
TPBG 21983 Q9Z0L0
TPBG 83684 Q5PQV5
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Top anti-TPBG Antikörper auf antikoerper-online.de

Showing 10 out of 57 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Maus Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Maus Schaf Unkonjugiert CyTOF, FACS, ICC, WB Detection of 5T4 in D3 Mouse Cell Line by Flow Cytometry. Retinoic acid-treated D3 mouse embryonic stem cell line was stained with Sheep Anti-Mouse 5T4 Antigen Affinity-purified Polyclonal Antibody. 5T4 in D3 Mouse Cell Line. 5T4 was detected in immersion fixed D3 mouse embryonic stem cell line using Sheep Anti-Mouse 5T4 Antigen Affinity-purified Polyclonal Antibody  at 10 ug/mL for 3 hours at room temperature. Cells were stained using the NorthernLightsル 557-conjugated Anti-Sheep IgG Secondary Antibody (red 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$416.30
Details
Human Kaninchen Unkonjugiert WB TPBG Antibody (Center)  western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the TPBG antibody detected the TPBG protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus Fluorescein FACS Detection of 5T4 in BG01V Human Cells by Flow Cytometry. BG01V human embryonic stem cells were stained with Mouse Anti-Human 5T4 Fluorescein-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$299.00
Details
Human Maus PE FACS Detection of 5T4 in BG01V Human Cells by Flow Cytometry. BG01V human embryonic stem cells were stained with Mouse Anti-Human 5T4 PE-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$357.65
Details
Human Maus APC FACS Detection of 5T4 in BG01V Human Cells by Flow Cytometry. BG01V human embryonic stem cells were stained with Mouse Anti-Human 5T4 APC-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$416.30
Details
Human Maus Unkonjugiert CyTOF, FACS Detection of 5T4 in BG01V Human Cells by Flow Cytometry. Differentiated BG01V human embryonic stem cells were stained with Mouse Anti-Human 5T4 Monoclonal Antibody. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$299.00
Details
Maus Schaf Fluorescein FACS Detection of 5T4 in D3 Mouse Cell Line by Flow Cytometry. D3 mouse embryonic stem cell line was stained with Sheep Anti-Mouse 5T4 Fluorescein-conjugated Antigen Affinity-purified Polyclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$299.00
Details
Maus Schaf APC FACS Detection of 5T4 in D3 Mouse Cell Line by Flow Cytometry. D3 mouse embryonic stem cell line was stained with Sheep Anti-Mouse 5T4 APC-conjugated Antigen Affinity-purified Polyclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$410.55
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details

TPBG Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-TPBG Antikörper

  1. Mouse (Murine) Polyclonal TPBG Primary Antibody für CyTOF, FACS - ABIN4900172 : Takahashi, Ogawa, Yoshihara, Asahina, Kinoshita, Kitano, Kitsuki, Tatsumi, Okuda, Tatsumi, Wanaka, Hirai, Stern, Tsuboi: A Subtype of Olfactory Bulb Interneurons Is Required for Odor Detection and Discrimination Behaviors. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen TPBG Interaktionspartner

Human Trophoblast Glycoprotein (TPBG) Interaktionspartner

  1. We obtained GWS evidence (P < 2.7 x 10(-6)) for gene-based association in the total sample with a novel locus, TPBG (P = 1.8 x 10(-6)).

  2. In conclusion, the present study provided evidence that TPBG is involved in PDAC metastasis, and that TPBG and its associated signaling pathways may be a suitable target for pancreatic ductal adenocarcinoma therapy.

  3. 5T4 expression is mechanistically associated with the directional movement of cells through epithelial mesenchymal transition, facilitation of CXCL12 (zeige CXCL12 Antikörper)/CXCR4 (zeige CXCR4 Antikörper) chemotaxis, blocking of canonical Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) while favouring non-canonical pathway signalling

  4. Tyrosine 325 plus the leucine-rich repeat 1 surface centered on a second exposed aromatic residue, phenylalanine 97, are essential for inhibition of Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) signaling.

  5. The surface expression of 5T4 marks the use of the CXCR4 (zeige CXCR4 Antikörper) rather than the CXCR7 (zeige CXCR7 Antikörper) receptor, with distinct consequences for CXCL12 (zeige CXCL12 Antikörper) exposure.

  6. 5T4 is a potential new antigen for targeted therapies such as immunotherapy in MPM, as it is overexpressed on mesothelioma cells and recognised by 5T4-specific cytotoxic T-cells.

  7. Glycosylation and epitope mapping of the 5T4 glycoprotein oncofoetal antigen

  8. Results sugest that 5T4 is a transient marker of human embryonic stem cell differentiation & that 5T4 phenotype, colony seeding density and culture conditions influence the maintenance of pluripotent hES (zeige RRBP1 Antikörper) cells and their differentiation to neural lineages.

  9. there is a repertoire of CD8 T cell recognition of 5T4 in normal human donors and some candidate HLA-A*0201 epitopes have been identified

  10. the mRNA expression of trophoblast glycoprotein is up-regulated in cells circulating within blood from women with preeclampsia.

Mouse (Murine) Trophoblast Glycoprotein (TPBG) Interaktionspartner

  1. The surface expression of 5T4 marks the use of the CXCR4 (zeige CXCR4 Antikörper) rather than the CXCR7 (zeige CXCR7 Antikörper) receptor, with distinct consequences for CXCL12 (zeige CXCL12 Antikörper) exposure.

  2. 5T4 overexpression in newborn olfactory bulb interneurons facilitates their dendritic arborization even under a sensory input-deprived condition.

  3. molecular interaction of 5T4 and CXCR4 (zeige CXCR4 Antikörper) occurring at the cell surface which directly facilitates the biological response to CXCL12 (zeige CXCL12 Antikörper)

  4. Spry4 (zeige SPRY4 Antikörper) and Tpbg/5T4 were detected in Kit-immunoreactive cells only in Kit(K641E), but not in Kit(WT/WT) animals.

  5. Glycosylation and epitope mapping of the 5T4 glycoprotein oncofoetal antigen

  6. 5T4 glycoprotein expression is associated with early differentiative events of embryonic stem cells

  7. A limited expression profile of 5T4 may contribute to the migration of actively cycling, undifferentiated epithelial progenitor cells during embryogenesis

  8. Because 5T4 is known to interact with actin cytoskeleton, these observations suggest that 5T4 is involved in the formation or maintenance of strata-specific dendritic ramification or synaptic connection of subsets of local interneurons.

  9. E-cadherin (zeige CDH1 Antikörper) protein stabilizes cortical actin cytoskeletal arrangement in embryonic stem cells, and this can prevent cell surface localization of the promigratory 5T4 antigen.

TPBG Antigen-Profil

Protein Überblick

This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein.

Genbezeichner und Symbole assoziert mit TPBG

  • trophoblast glycoprotein (TPBG) Antikörper
  • trophoblast glycoprotein (Tpbg) Antikörper
  • trophoblast glycoprotein b (tpbgb) Antikörper
  • trophoblast glycoprotein (tpbg) Antikörper
  • 5T4 Antikörper
  • 5T4AG Antikörper
  • AW495680 Antikörper
  • M6P1 Antikörper
  • tpbg Antikörper

Bezeichner auf Proteinebene für TPBG

5T4 oncofetal antigen , 5T4 oncofetal trophoblast glycoprotein , 5T4 oncotrophoblast glycoprotein , trophoblast glycoprotein , sc:d0347 , Trophoblast glycoprotein , trophoblast glycoprotein-like

GENE ID SPEZIES
7162 Homo sapiens
21983 Mus musculus
83684 Rattus norvegicus
462850 Pan troglodytes
481899 Canis lupus familiaris
540358 Bos taurus
772098 Gallus gallus
792712 Danio rerio
100286624 Salmo salar
100379816 Xenopus (Silurana) tropicalis
100405225 Callithrix jacchus
100444954 Pongo abelii
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