Tripartite Motif Containing 25 Proteine (TRIM25)

The protein encoded by TRIM25 is a member of the tripartite motif (TRIM) family. Zusätzlich bieten wir Ihnen TRIM25 Antikörper (149) und TRIM25 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TRIM25 7706 Q14258
TRIM25 217069 Q61510
Ratte TRIM25 TRIM25 494338  
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Top TRIM25 Proteine auf antikoerper-online.de

Showing 4 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
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TRIM25 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Tripartite Motif Containing 25 (TRIM25) Interaktionspartnern

Human Tripartite Motif Containing 25 (TRIM25) Interaktionspartner

  1. The RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain, which we postulate to be a novel RNA-binding domain.

  2. TRIM25 inhibits hepatocellular carcinoma progression by targeting MTA1 (zeige MTA1 Proteine).

  3. TRIM25 is a key determinant of breast cancer metastasis.

  4. V interaction with TRIM25 and RIG-I (zeige DDX58 Proteine) prevents TRIM25-mediated ubiquitination of RIG-I (zeige DDX58 Proteine) and disrupts downstream RIG-I (zeige DDX58 Proteine) signaling to the mitochondrial antiviral signaling protein (zeige MAVS Proteine).

  5. HPV E6 oncoprotein antagonizes the activation of the cytoplasmic innate immune sensor RIG-I (zeige DDX58 Proteine) by targeting its upstream regulatory enzymes TRIM25 and USP15 (zeige USP15 Proteine). We further show that the RIG-I (zeige DDX58 Proteine) signaling cascade is important for an antiviral innate immune response to HPV16 infection

  6. this study shows thatTRIM25 targets ERG (zeige ERG Proteine) for degradation in prostate cancer

  7. TRIM25 actively participates in higher-order assembly of the RIG-I (zeige DDX58 Proteine) signalosome.

  8. Our results indicate that TRIM25 is associated with cisplatin resistance and 14-3-3sigma-MDM2 (zeige MDM2 Proteine)-p53 (zeige TP53 Proteine) signaling pathway is involved in this process, suggesting targeting TRIM25 may be a potential strategy for the reversal of cisplatin resistance.

  9. expression of TRIM25 might be critical for lung cancer cell migration, proliferation as well as doxorubicin resistance.

  10. Disturbed p53 (zeige TP53 Proteine)-MDM2 (zeige MDM2 Proteine) feedback loop contributing to the pathogenesis of thoracic aortic dissection may be linked to TRIM25 overexpression.

Mouse (Murine) Tripartite Motif Containing 25 (TRIM25) Interaktionspartner

  1. TRIM25 as a key determinant of breast cancer metastasis.

  2. Studies indicated that mice with disrupted Trim25 were viable and fertile, uterine response to oestrogen was greatly attenuated and the uteri were underdeveloped.

  3. Two key residues (Asp (zeige C3 Proteine)(488) and Trp (zeige TYRP1 Proteine)(621)) in the TRIM25 B30.2 domain are critical for binding to the RIG-I (zeige DDX58 Proteine) CARDs.

  4. Two well-known E3 ubiquitin ligases, Trim25 (also called Efp) and Trim71 (zeige TRIM71 Proteine) (also called Lin41 (zeige TRIM71 Proteine)), are validated as RNA-binding proteins, revealing a potential link between RNA biology and protein-modification pathways.

TRIM25 Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

Genbezeichner und Symbole assoziert mit TRIM25

  • E3 ubiquitin/ISG15 ligase TRIM25 (LOC100146440)
  • tripartite motif containing 25 (trim25)
  • E3 ubiquitin/ISG15 ligase TRIM25-like L homeolog (LOC100490741.L)
  • tripartite motif containing 25 (TRIM25)
  • microRNA 3614 (MIR3614)
  • tripartite motif-containing 25 (Trim25)
  • AA960166 Protein
  • AL022677 Protein
  • Efp Protein
  • MGC130751 Protein
  • RNF147 Protein
  • Z147 Protein
  • Zfp147 Protein
  • zgc:55773 Protein
  • Znf147 Protein

Bezeichner auf Proteinebene für TRIM25

tripartite motif-containing 25 , E3 ubiquitin/ISG15 ligase TRIM25 , tripartite motif containing 25 , RING finger protein 147 , estrogen-responsive finger protein , tripartite motif protein TRIM25 , tripartite motif-containing protein 25 , ubiquitin/ISG15-conjugating enzyme TRIM25 , zinc finger protein 147 (estrogen-responsive finger protein) , zinc finger protein-147 , tripartite motif protein 25 , zinc finger protein 147

GENE ID SPEZIES
100146440 Equus caballus
393144 Danio rerio
431932 Xenopus laevis
455146 Pan troglodytes
100013883 Monodelphis domestica
100127751 Xenopus (Silurana) tropicalis
100440167 Pongo abelii
100599729 Nomascus leucogenys
7706 Homo sapiens
417401 Gallus gallus
510923 Bos taurus
491103 Canis lupus familiaris
217069 Mus musculus
494338 Rattus norvegicus
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