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This locus represents naturally occurring read-through transcription between the neighboring transmembrane emp24 protein transport domain containing 7 (TMED7) and toll-like receptor adaptor molecule 2 (TICAM2) genes. Zusätzlich bieten wir Ihnen TMED7 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.
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TMED7 is required to initiate and mediate the delivery of TLR4 (zeige TLR4 Antikörper) to the plasma membrane
TMED7 is essential for TAG-mediated disruption of the TRAM/TRIF (zeige TICAM2 Antikörper) complex and the degradation of toll-like receptor 4 (zeige TLR4 Antikörper)
This locus represents naturally occurring read-through transcription between the neighboring transmembrane emp24 protein transport domain containing 7 (TMED7) and toll-like receptor adaptor molecule 2 (TICAM2) genes. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with the products of each individual gene. This fusion product functions to negatively regulate the adaptor MyD88-independent toll-like receptor 4 pathway.
p24 family protein gamma-3 , p24gamma3 , transmembrane emp24 domain-containing protein 7 , UV36Sp6 ultraviolet B radiation-activated UV36 , transmembrane emp24 protein transport domain containing 7 , transmembrane p24 trafficking protein 7 L homeolog , p24 gamma 3