anti-Transmembrane 7 Superfamily Member 4 (TM7SF4) Antikörper

TM7SF4 encodes a seven-pass transmembrane protein that is primarily expressed in dendritic cells. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TM7SF4 299889  
TM7SF4 81501 Q9H295
TM7SF4 75766 Q7TNJ0
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Top anti-Transmembrane 7 Superfamily Member 4 Antikörper auf antikoerper-online.de

Showing 10 out of 16 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-TM7SF4 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:12500  Positive Control:  OVCAR-3 cell lysate DCSTAMP is supported by BioGPS gene expression data to be expressed in OVCAR3 WB Suggested Anti-TM7SF4  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:12500  Positive Control: OVCAR-3 cell lysate  DCSTAMP is supported by BioGPS gene expression data to be expressed in OVCAR3 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
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Hund Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
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Human Maus APC FACS Detection of DC-STAMP in Human Denditic Cells by Flow Cytometry. Mature human monocyte-derived dendritic cells were stained with Mouse Anti-Human CD83 Fluorescein-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$396.63
Details
Human Maus Alexa Fluor 488 FACS Detection of DC-STAMP in Human Denditic Cells by Flow Cytometry. Mature human monocyte-derived dendritic cells treated with 20 ng/mL Recombinant Human IL-4. 100 μg Anmelden zum Anzeigen 11 bis 13 Tage
$406.80
Details
Human Maus Unkonjugiert CyTOF, FACS Detection of DC-STAMP in Human Mature Dendritic Cells by Flow Cytometry. Human mature dendritic cells derived from CD14+ Human peripheral blood mononuclear cells (PBMCs) treated with 20 ng/mL Recombinant Human IL-4. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$297.19
Details
Human Kaninchen Unkonjugiert WB Western Blot: DC-STAMP/TM7SF4 Antibody [NBP1-79329] - Titration: 0.2-1 ug/ml, Positive Control: OVCAR-3 cell lysate. 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$488.73
Details
Human Kaninchen Unkonjugiert WB   50 μL Anmelden zum Anzeigen 16 Days
$308.12
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Human Maus Alexa Fluor 350 FACS   100 μg Anmelden zum Anzeigen 11 bis 13 Tage
$406.80
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Human Maus Alexa Fluor 405 FACS   100 μg Anmelden zum Anzeigen 11 bis 13 Tage
$406.80
Details
Human Maus Alexa Fluor 647 FACS   100 μg Anmelden zum Anzeigen 11 bis 13 Tage
$406.80
Details

Am meisten referenzierte anti-Transmembrane 7 Superfamily Member 4 Antikörper

  1. Mouse (Murine) Polyclonal TM7SF4 Primary Antibody für IF - ABIN549034 : Staege, Brauchlin, Schoedon, Schaffner: Two novel genes FIND and LIND differentially expressed in deactivated and Listeria-infected human macrophages. in Immunogenetics 2001 (PubMed)
    Show all 5 Pubmed References

  2. Human Monoclonal TM7SF4 Primary Antibody für FACS - ABIN4897340 : de la Rica, García-Gómez, Comet, Rodríguez-Ubreva, Ciudad, Vento-Tormo, Company, Álvarez-Errico, García, Gómez-Vaquero, Ballestar: NF-κB-direct activation of microRNAs with repressive effects on monocyte-specific genes is critical for osteoclast differentiation. in Genome biology 2015 (PubMed)

Weitere Antikörper gegen Transmembrane 7 Superfamily Member 4 Interaktionspartner

Human Transmembrane 7 Superfamily Member 4 (TM7SF4) Interaktionspartner

  1. TM7SF4 may be involved in the progression of lung cancer.

  2. Our results suggest that the rare genetic variant of TM7SF4 gene, found in our French-Canadian cohort of patients with Paget's disease of bone and which encodes the DC-STAMP protein, increase the number of nuclei per multinucleated cells and affect DC-STAMP expression during osteoclastogenesis in Paget's disease of bone.

  3. TM7SF4 plays an essential role in regulating cell cycle progression in breast cancer.

  4. The EP in TKA differed from EP in aseptically failed THA by lower CCL3 and DC-STAMP mRNA and protein expression. EP of all studied inflammatory and osteoclastogenic molecules were similar in knee and hip OA.

  5. Our findings also suggest that next generation sequencing may help explore the pathogenesis and aid the diagnosis of Juvenile Paget's disease.

  6. Rs62620995 in the TM7SF4 gene was found to have a marginal association with Paget's disease of bone in the French-Canadian population.

  7. DC-STAMP inhibition by RNA interference consequently suppressed fusion and bone resorption of human osteoclasts.

  8. An interaction between OS9 and DC-STAMP was confirmed by yeast-2-hybrid analysis and cellular colocalization.ER-to-Golgi translocation of DC-STAMP following TLR stimulation in CHO cells was demonstrated, involving the DC-STAMP/OS9 interaction. The data indicate that OS9 is critically involved in ER-to-Golgi transport of DC-STAMP, and may be important in both myeloid differentiation and cell fusion.

  9. DC-STAMP is an ITIM-bearing molecule. Based on the 4 distinct patterns of DCSTAMP on human PBMC, it has potential to serve as a susceptible biomarker of psoriasis (Ps) as well as severity marker of Psoriatic Arthritis (PsA).

  10. Results show that T cells played a pivotal role in a new in vitro Langhans giant cells (LGCs) formation system, in which DC-STAMP was involved, and occurred via a molecular mechanism that involved CD40-CD40L interaction and IFN-gamma secretion.

  11. genetic risk for Paget's disease of bone is associated with variants close to CSF1, OPTN, TM7SF4, and TNFRSF11A genes

  12. DC-STAMP interacts with ER-resident transcription factor LUMAN which becomes activated during DC maturation.

  13. The dendritic cell-specific transmembrane protein is a multimembrane-spanning protein preferentially expressed by human DC (hDC).

  14. 2 differentially expressed genes over-expressed in papillary thyroid cancers were identified as DC-STAMP and type I collagen A1

Mouse (Murine) Transmembrane 7 Superfamily Member 4 (TM7SF4) Interaktionspartner

  1. These results suggested that hyperphosphatemia in the patients with CKD suppresses bone resorption by inhibiting osteoclastogenesis, and this impairs the regulation of bone metabolism.

  2. Immunoreceptor tyrosine-based inhibitory motif DC-STAMP is a functional motif that regulates osteoclast differentiation through the NFATc1/Ca(2+) axis.

  3. These results suggest that Luman regulates the multinucleation of osteoclasts by promoting cell fusion of mononuclear osteoclasts through DC-STAMP induction and intracellular distribution during osteoclastogenesis.

  4. miR-7b inhibits osteoclastogenesis and cell-cell fusion by directly targeting DC-STAMP.

  5. our data indicate that Pin1 is a determinant of bone mass through the regulation of the osteoclast fusion protein DC-STAMP

  6. Mechanical vibration of osteoclast precursor cells reduces DC-STAMP expression in osteoclast precursor cells.

  7. DC-STAMP, Siglec-15, Tspan7 and Mst1r expression was downregulated by docosahexaenoic acid, but not eicosapentaenoic acid during osteoclastogenesis in vitro.

  8. Results indicate that NFATc1 binding to the DC-STAMP promoter was inhibited by 60.9% with RvE1 treatment.

  9. Strawberry notch homologue 2 regulates osteoclast fusion by enhancing the expression of DC-STAMP.

  10. These results suggest that short-term mechanical stress strongly inhibits osteoclastogenesis through the downregulation of DC-STAMP.

  11. Fusogenic mechanisms in macrophage-lineage cells are regulated via OC-STAMP and DC-STAMP.

  12. found that DC-STAMP, a key regulator of osteoclast cell fusion, is a direct target gene of Tal1 and show that Tal1 represses DC-STAMP expression by counteracting the activating function of the transcription factors PU.1 and MITF

  13. DC-STAMP is an ITIM-bearing molecule. Based on the 4 distinct patterns of DCSTAMP on human PBMC, it has potential to serve as a susceptible biomarker of psoriasis (Ps) as well as severity marker of Psoriatic Arthritis (PsA).

  14. regulates cytokine production and T-cell stimulatory capacity of LPS-matured dendritic cells

  15. CCN2 expressed during osteoclastogenesis promotes osteoclast formation via induction of and interaction with DC-STAMP

  16. DC-STAMP is expressed on osteoclast precursors as a dimer. RANKL induces osteoclastogenesis by stimulating DC-STAMP internalization in some osteoclast progenitors.

  17. DC-STAMP has an essential role in osteoclastogenesis.

  18. DC-STAMP expression is regulated differently in osteoclasts and macrophage giant cells.

  19. the expression of DC-STAMP affects myeloid development of hematopoietic progenitor cells, specifically suppressing granulocytic development

  20. dendritic cell antigen presentation activity is up-regulated in DC-STAMP-deficient mice; autoimmunity is present

Transmembrane 7 Superfamily Member 4 (TM7SF4) Antigen-Profil

Protein Überblick

This gene encodes a seven-pass transmembrane protein that is primarily expressed in dendritic cells. The encoded protein is involved in a range of immunological functions carried out by dendritic cells. This protein plays a role in osteoclastogenesis and myeloid differentiation. Alternate splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit TM7SF4

  • dendrocyte expressed seven transmembrane protein (Dcstamp) Antikörper
  • dendrocyte expressed seven transmembrane protein (DCSTAMP) Antikörper
  • 4833414I07Rik Antikörper
  • DC-STAMP Antikörper
  • FIND Antikörper
  • hDC-STAMP Antikörper
  • mDC-STAMP Antikörper
  • TM7SF4 Antikörper

Bezeichner auf Proteinebene für TM7SF4

transmembrane 7 superfamily member 4 , dendritic cell-specific transmembrane protein , DC-specific transmembrane protein , Dendritic cells (DC)-specific transmembrane protein , IL-4-induced protein , IL-Four (IL-4) induced , IL-Four INDuced , IL-four-induced protein , dendrocyte-expressed seven transmembrane protein

GENE ID SPEZIES
299889 Rattus norvegicus
420265 Gallus gallus
472835 Pan troglodytes
512133 Bos taurus
695237 Macaca mulatta
100062879 Equus caballus
100340223 Oryctolagus cuniculus
100394920 Callithrix jacchus
100437772 Pongo abelii
100474957 Ailuropoda melanoleuca
100158149 Sus scrofa
81501 Homo sapiens
75766 Mus musculus
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