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a zinc binding nuclear protein in sperm [RGD, Feb 2006].. Zusätzlich bieten wir Ihnen TNP2 Antikörper (34) und TNP2 Kits (11) und viele weitere Produktgruppen zu diesem Protein an.
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the quantity of PRM1 (zeige PRM1 Proteine), PRM2 (zeige PRM2 Proteine), and TNP2 transcripts and the PRM1 (zeige PRM1 Proteine)/PRM2 (zeige PRM2 Proteine) mRNA ratio affect spermiogenesis, sperm morphology
MiR (zeige MLXIP Proteine)-122 may influence spermatozoa-like cells by suppressing TNP2 expression and inhibiting the expression of proteins associated with sperm development.
analysis of the TNP2 gene did not show any association with infertility.
We found significantly lower levels of HILS1, TNP1 (zeige TNP1 Proteine), and TNP2 transcripts in spermatozoa from asthenozoospermic men compared to normozoospermic men.
The presence of transition proteins (TP1 (zeige RPLP2 Proteine) and/or TP2 (zeige TERT Proteine)) in spermatids in semen indicates inhibition in the differentiation pathway from round spermatids to spermatozoa in infertile men.
Acetylation of transition protein 2 (TP2) by KAT3B (p300 (zeige EP300 Proteine)) alters its DNA condensation property and interaction with putative histone chaperone NPM3 (zeige NPM3 Proteine).
juvenile spermatids from Ip6k1 (zeige IP6K1 Proteine)(-/-) mice display premature expression of the transition protein TNP2 and the protamine PRM2 (zeige PRM2 Proteine) due to translational derepression.
The association of Tp2 (zeige TERT Proteine) expression via binding to the conserved RNA binding motifs of GRTH (zeige DDX25 Proteine) protein and the basis for understanding GRTH (zeige DDX25 Proteine) in the regulation of the genes essential for germ cell elongation and completion of spermatogenesis is revealed.
Testis-specific (zeige AIF1 Proteine) miRNA-469 up-regulated in gonadotropin-regulated testicular RNA helicase (GRTH/DDX25 (zeige DDX25 Proteine))-null mice silences transition protein 2 and protamine 2 (zeige PRM2 Proteine) messages at sites within coding region: implications of its role in germ cell development.
Cannabinoid receptor 1 influences chromatin remodeling in mouse spermatids by affecting content of transition protein 2 mRNA.
The elevated levels of the remaining TP in Tnp-mutant mice appeared to be a consequence of the prolonged nucleus retention, rather than increased synthesis
Epididymal sperm from Tnp2 null genotypes demonstrated a general decrease in normal morphology, motility, chromatin condensation, and degree of protamine 2 (zeige PRM2 Proteine) processing with decreasing levels of transition proteins in mutant sperm.
Specific microRNAs, such as Mirn122a, could be involved in the posttranscriptional regulation of mRNAs such as Tnp2 in the mammalian testis.
These results show clearly that a strict temporal and stage-specific Tnp2 translation is necessary for the correct differentiation of round spermatids into mature spermatozoa and for male fertility.
Data show that Parp2 (zeige PARP2 Proteine) interacts significantly with both the transition protein TP2 (zeige TERT Proteine) and the transition chaperone HSPA2, whereas Parp1 (zeige PARP1 Proteine) binds weakly to HSPA2 (zeige HSPA2 Proteine).
SNP g.1536 C>T in the TNP2 3'-UTR, which altered the binding of TNP2 with bta-miR (zeige MYLIP Proteine)-154, was found to be associated with the semen quality traits of Chinese Holstein bulls
a zinc binding nuclear protein in sperm
, nuclear transition protein 2
, transition protein 2 (alt.)
, haploid expressed, male germcell specific, chromatin binding