Transient Receptor Potential Cation Channel, Subfamily M, Member 5 Proteine (TRPM5)

TRPM5 encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. Zusätzlich bieten wir Ihnen TRPM5 Antikörper (52) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TRPM5 29850 Q9NZQ8
TRPM5 56843 Q9JJH7
Ratte TRPM5 TRPM5 365391  
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Showing 4 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details

TRPM5 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine) ,
,

Weitere Proteine zu Transient Receptor Potential Cation Channel, Subfamily M, Member 5 (TRPM5) Interaktionspartnern

Human Transient Receptor Potential Cation Channel, Subfamily M, Member 5 (TRPM5) Interaktionspartner

  1. genetic association studies in populations in Northern Europe, Maghreb, and Sri (zeige SRI Proteine) Lanka: Data suggest that SNPs in TAS2R50 (rs1376251), TRPM5 (rs800345), and TAS2R16 (zeige TAS2R16 Proteine) (rs860170) are associated with cultural food preferences; TAS2R16 (zeige TAS2R16 Proteine) (rs860170) strongly differentiates populations and is associated to salicin bitterness perception. (TAS2R = taste receptor type 2)

  2. Our results suggest roles of TRPM3 (zeige TRPM3 Proteine) and TRPM5 gene variants in the susceptibility to or clinical expression of Systemic sclerosis

  3. The PKC (zeige PRRT2 Proteine)-dependent effect of GLP-1 (zeige GCG Proteine) on membrane potential and electrical activity was mediated by activation of Na(+)-permeable TRPM4 (zeige TRPM4 Proteine) and TRPM5 channels by mobilization of intracellular Ca(2 (zeige CA2 Proteine)+) from thapsigargin-sensitive Ca(2 (zeige CA2 Proteine)+) stores

  4. In a Turkish population, genetic polymorphism in TRPM5 genes modify individual susceptibility to metabolic syndrome.

  5. TRPM5-mediated Na(+) entry to promote Ca(2+) uptake via an NCX to trigger MUC5AC secretion

  6. TrpM5 expression was similar throughout the olfactory glomeruli.

  7. The TRPM5 gene rs34551253 (Ala456Thr) polymorphism may be associated with increased risk of developing primary open angle glaucoma in the Turkish population.

  8. AZIN1 (zeige AZIN1 Proteine) rs2679757 and TRPM5 rs886277 are associated with the risk of HBV-related liver cirrhosis in Chinese.

  9. extracellular Zn(2+) inhibits TRPM5 channels, and the residues in the outer pore loop of TRPM5 are critically involved in the inhibition.

  10. common TRPM5 variants are likely to be associated with prediabetic phenotypes; and this may in turn contribute to the development of type 2 diabetes mellitus

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily M, Member 5 (TRPM5) Interaktionspartner

  1. Both TRPM4 (zeige TRPM4 Proteine) and TRPM5 are required for normal responses to bitter, sweet, and umami stimuli.

  2. This physiological and behavioral results indicate that TRPM5-MCs (zeige SMCP Proteine) play a protective role in maintaining the olfactory function of the mammalian main olfactory epithelium.

  3. conclude that nAChR (zeige CHRNA4 Proteine) subunits are expressed in Trpm5-positive TRCs and their expression levels are differentially altered by chronic oral exposure to nicotine and ethanol

  4. propose that Skn-1a/Pou2f3 (zeige POU2F3 Proteine) is the master regulator for the generation of the Trpm5-expressing microvillous cells in multiple tissues

  5. This study demonstrate that Trpm5 is transiently expressed in a subpopulation of mature OSNs in the embryonic olfactory epithelium, indicating that Trpm5 channels could play a specific role in utero during a narrow developmental time window.

  6. The PKC-dependent effect of GLP-1 (zeige GCG Proteine) on membrane potential and electrical activity was mediated by activation of Na(+)-permeable TRPM4 (zeige TRPM4 Proteine) and TRPM5 channels by mobilization of intracellular Ca(2 (zeige CA2 Proteine)+) from thapsigargin-sensitive Ca(2 (zeige CA2 Proteine)+) stores

  7. The present findings confirm and extend our recent findings that Trpm5 KO mice express significant preferences for 8% glucose and galactose.

  8. Skn-1a (zeige POU2F3 Proteine) is expressed in a minority of Mash1 (zeige ASCL1 Proteine)-positive olfactory progenitor cells and a majority of Trpm5-expressing microvillous cells in the main olfactory epithelium.

  9. The Trpm5 (but not T1r3 (zeige TAS1R3 Proteine)) signaling is essential for starch preference, Trpm5 KO mice can learn to prefer starch based on its postoral effects.

  10. This study show that olfactory sensory neurons expressing TRPM5 respond to pheromones, but not to regular odors through the opening of CNG (zeige CNGA1 Proteine) channels leading to Ca2 (zeige CA2 Proteine)+ gating of TRPM5

TRPM5 Protein Überblick

Protein Überblick

This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele.

Genbezeichner und Symbole assoziert mit TRPM5

  • transient receptor potential cation channel subfamily M member 5 (TRPM5)
  • transient receptor potential cation channel, subfamily M, member 5 (Trpm5)
  • transient receptor potential cation channel, subfamily M, member 5 (trpm5)
  • 9430099A16Rik Protein
  • LTrpC-5 Protein
  • Ltrpc5 Protein
  • Mtr1 Protein

Bezeichner auf Proteinebene für TRPM5

transient receptor potential cation channel, subfamily M, member 5 , transient receptor potential cation channel subfamily M member 5-like , LTrpC-5 , MLSN1 and TRP-related , MLSN1- and TRP-related gene 1 protein , long transient receptor potential channel 5 , transient receptor potential cation channel subfamily M member 5 , long transient receptor potential-related channel 5

GENE ID SPEZIES
100299596 Bos taurus
100457245 Pongo abelii
100466736 Ailuropoda melanoleuca
100533558 Sus scrofa
466320 Pan troglodytes
705070 Macaca mulatta
29850 Homo sapiens
483668 Canis lupus familiaris
56843 Mus musculus
557722 Danio rerio
365391 Rattus norvegicus
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