Transformer 2 beta Homolog (Drosophila) Proteine (TRA2B)

TRA2B encodes a nuclear protein which functions as sequence-specific serine/arginine splicing factor which plays a role in mRNA processing, splicing patterns, and gene expression. Zusätzlich bieten wir Ihnen TRA2B Antikörper (54) und TRA2B Kits (5) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TRA2B 6434 P62995
TRA2B 20462 P62996
Ratte TRA2B TRA2B 117259 P62997
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Top TRA2B Proteine auf antikoerper-online.de

Showing 6 out of 8 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,370.21
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,370.21
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$888.80
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Escherichia coli (E. coli) Human His tag   100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$800.00
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,755.50
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TRA2B Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Transformer 2 beta Homolog (Drosophila) (TRA2B) Interaktionspartnern

Human Transformer 2 beta Homolog (Drosophila) (TRA2B) Interaktionspartner

  1. Findings demonstrate that Tra2b is upregulated in non-small cell lung cancer (NSCLC) and is associated with poor prognosis. Furthermore, Tra2b was identified as a direct target of miR-335. These results indicate that the interaction between miR-335 and Tra2b may play a vital role in the pathogenesis of NSCLC.

  2. It seems that a new signaling axis, SIRT1-SFRS10-LPIN1 axis, acting in the pathogenesis of alcoholic fatty liver disease exists.

  3. that TRA2beta promotes glioma cell growth and migration, and could be a candidate for molecular targeting during gene therapy treatments of glioma

  4. Tra2beta was significantly upregulated in prostate carcinoma, and multivariate analysis confirmed Tra2beta as an independent prognostic factor.

  5. Overexpression of either Tra2alpha or Tra2beta results in a marked reduction in HIV-1 Gag/ Env expression.

  6. Results showed that HNRNPG and HTRA2-BETA1 were specific antagonistic regulators of ERa exon7 splicing and increased HNRNPG levels were associated with improved clinical outcome of endometrial cancer through up-regulation of ERaD7 expression.

  7. findings suggest that Tra2beta regulates apoptosis by modulating Bcl-2 expression through its competition with miR-204. This novel function may have a crucial role in tumor growth.

  8. SRPK1 is a regulator of Tra2beta1 splicing function and individual domains engage in considerable cross-talk, assuming novel functions with regard to RNA binding, splicing, and catalysis.

  9. Simultaneous depletion of Tra2alpha and Tra2beta induces substantial shifts in splicing of endogenous Tra2beta target exons, and both constitutive and alternative target exons are under dual Tra2alpha-Tra2beta control.

  10. Results indicate that transformer 2beta (Tra2beta) was involved in the tumorigenesis of NSCLC and might be a potential therapeutic target of non-small cell lung cancer (NSCLC).

  11. Facilitating Tra2beta-dependent inclusion of exons in target pre-mRNAs.

  12. Oxidative stress-responsive Transformer 2beta may play an important role in colon cancer growth.

  13. SFRS10 is not expressed in normal human retinae but is upregulated in Age-related macular degeneration retinae.

  14. Specific induction of hTra2beta1 due to Alternative splicing is associated with epithelial ovarian cancer.

  15. analysis of mechanisms by which the subcellular and subnuclear localization of Tra2beta proteins are regulated

  16. findings show the inclusion of both HIV-1 exon 3 and vpr mRNA processing is promoted by an exonic splicing enhancer (ESEvpr) localized between exonic splicing silencer ESSV and 5'ss D3; the ESEvpr sequence was found to be bound by members of the Tra2 protein family

  17. reduced expression of SFRS10, as observed in tissues from obese humans, alters LPIN1 splicing, induces lipogenesis, and therefore contributes to metabolic phenotypes associated with obesity.

  18. nuclear hnRNP G level as well as hTra2-beta1 level were independent prognostic factors for endometrial cancer progression-free survival

  19. Results indicates that the Human Transformer2-beta RNA recognition motif recognizes two types of RNA sequences in different RNA binding modes.

  20. DARPP-32 changes the usage of tra2-beta1 dependent alternative exons in a concentration-dependent manner, suggesting that the DARPP-32:tra2-beta1 interaction is a molecular link between signaling pathways and pre-mRNA processing.

Mouse (Murine) Transformer 2 beta Homolog (Drosophila) (TRA2B) Interaktionspartner

  1. results indicate that high expression level of Tra2-beta1 is responsible for increased SMN2 exon 7 inclusion in the testis of SMA mice.

  2. Maturation of mesenteric artery smooth muscle involves TRA2beta mediated Mypt1 exon 24 splicing.

  3. TRA2B has a role in regulating protein kinase C deltaI splice variant expression during 3T3L1 preadipocyte cell cycle

  4. Tra2b regulates splicing events essential for maintaining neuronal viability during development.

  5. TRA2B is essential for proper development of the cerebral cortex.

  6. Sfrs10 expression is observed in rod photoreceptors in a peri-nuclear pattern.

  7. Tra2beta, by regulating the splicing of Mypt1 E23, sets the sensitivity of smooth muscle to cGMP-mediated relaxation.

  8. Normal activation of these regulated exons depends on multiple Tra2b binding sites, and significant mis-regulation of these exons is observed during mouse development when Tra2b is removed.

TRA2B Protein Überblick

Protein Überblick

This gene encodes a nuclear protein which functions as sequence-specific serine/arginine splicing factor which plays a role in mRNA processing, splicing patterns, and gene expression. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit TRA2B

  • transformer 2 beta homolog (Drosophila) (tra2b)
  • transformer 2 beta homolog L homeolog (tra2b.L)
  • transformer 2 beta homolog (Drosophila) (TRA2B)
  • transformer 2 beta homolog (TRA2B)
  • transformer 2 beta homolog (Drosophila) (Tra2b)
  • transformer 2 beta homolog (Tra2b)
  • transformer 2 beta homolog (tra2b)
  • 5730405G21Rik Protein
  • D16Ertd266e Protein
  • Htra2-beta Protein
  • Sfrs10 Protein
  • SIG-41 Protein
  • Silg41 Protein
  • SRFS10 Protein
  • Srsf10 Protein
  • TRA2-BETA Protein
  • TRA2beta Protein
  • TRAN2B Protein
  • zgc:56612 Protein

Bezeichner auf Proteinebene für TRA2B

transformer-2 protein homolog beta , Splicing factor, arginine/serine-rich 10 , splicing factor, arginine/serine-rich 10 , splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) , transformer-2 beta , TRA-2 beta , transformer-2 protein homolog B , TRA2-beta , silica-induced gene 41 protein , RA301 , serine/arginine-rich splicing factor 10 , splicing factor, arginine/serine-rich, 10

GENE ID SPEZIES
100195215 Salmo salar
398448 Xenopus laevis
395403 Gallus gallus
6434 Homo sapiens
478663 Canis lupus familiaris
768108 Sus scrofa
615156 Bos taurus
20462 Mus musculus
117259 Rattus norvegicus
394172 Danio rerio
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