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TGOLN2 encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins.
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These results indicate that hepatitis E virus (HEV)forms membrane-associated particles in the cytoplasm, and that the released HEV particles with a lipid membrane retain the antigenicity of TGOLN2 on their surface.
These analyses do not provide support for the hypothesis that common genetic variation in TGOLN2 contributes significantly to the risk for attempted suicide in subjects with major mood disorders.
These data have identified different itineraries for the retrograde transport of Shiga toxin and TGN38 and distinct retromer components that regulate the transport of these cargos.
FXIII-A associated with podosomes & other structures adjacent to the plasma membrane, containing TGN46 & GM130 but not protein disulphide isomerase. FXIII-A was present in GM130-positive intracellular vesicles that could mediate its transport.
This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
trans-Golgi network integral membrane protein 2
, TGN38 homolog
, trans-Golgi network protein (46, 48, 51kD isoforms)
, trans-Golgi network protein TGN51
, trans-golgi network protein 2
, trans-Golgi network integral membrane protein TGN38
, trans-golgi network protein 1