the effects of salusin-alpha on the expression of some pro- and anti-inflammatory cytokines and on TNF-alpha (zeige TNF ELISA Kits)-induced inflammatory responses in human umbilical vein endothelial cells (HUVECs) were examined
Salusin-beta mediates high glucose-induced endothelial injury via disruption of AMPK (zeige PRKAA1 ELISA Kits) signaling pathway.
Study provides evidence results that salusin-beta induces foam formation and monocyte adhesion via miR155/NOX2 (zeige CYBB ELISA Kits)/NFkappaB (zeige NFKB1 ELISA Kits)-mediated ACAT-1 (zeige ACAT1 ELISA Kits) and VCAM-1 (zeige VCAM1 ELISA Kits) expressions in vascular smooth muscle cells.
These results demonstrate contrasting actions of salusin-beta in the control of water intake via the central and peripheral systems and highlight it as a potent endogenous antidipsogenic neuropeptide.
Salusin-beta is an antimicrobial peptide (zeige cAMP ELISA Kits) with potent antibacterial activity against Gram-positive microorganisms.
Salusin-beta accelerates the development of atherosclerotic lesions in APOE (zeige APOE ELISA Kits) knockout mice whilst salusin-alpha exerts anti-atherosclerotic effects.
Our results suggest that the interaction of tyrosine hydroxylase and mutant torsinA may contribute to the phenotype and reported dopaminergic dysfunction in torsinA-mediated dystonia.
the identification and characterization of two related peptides of 28 and 20 amino acids, which we designated salusin-alpha and salusin-beta. Salusins are translated from an alternatively spliced mRNA of TOR2A
Human salusin beta is a surrogate ligand of mouse MrgA1.
This gene encodes a member of the AAA family of adenosine triphosphatases with similarity to Clp proteases and heat shock proteins. Alternative splicing at this locus results in the translation of multiple isoforms of the encoded protein, some of which contain salusin peptides in the C-terminal region. These peptides may play roles in hypotension, myocardial growth and the induction of mitogenesis, and may also be involved in the pathogenesis of atherosclerosis.
torsin family 2, member A , prosalusin , torsin-2A , torsin-related protein 1 , Torsin family 2 member A
GENE ID | SPEZIES |
---|---|
417224 | Gallus gallus |
447294 | Xenopus laevis |
464752 | Pan troglodytes |
559805 | Danio rerio |
609191 | Canis lupus familiaris |
700203 | Macaca mulatta |
100036593 | Xenopus (Silurana) tropicalis |
100582595 | Nomascus leucogenys |
27433 | Homo sapiens |
534311 | Bos taurus |
30933 | Mus musculus |
362112 | Rattus norvegicus |