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TLL1 encodes an astacin-like, zinc-dependent, metalloprotease that belongs to the peptidase M12A family. Zusätzlich bieten wir Ihnen TLL1 Kits (11) und TLL1 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.
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Loss of BMP1 (zeige BMP1 Antikörper)-like proteinase activity is shown to result in markedly thinned and fragile skin with unusually densely packed collagen fibrils and delayed wound healing.
the proteinases encoded by Bmp1 (zeige BMP1 Antikörper) and Tll1 genes play essential roles in the development and maintenance of mouse dentin and periodontal ligaments.
The presented data demonstrate Bmp1 (zeige BMP1 Antikörper)/Tll1 products to be of profound importance to bone growth and modeling.
TLL1 mRNA levels significantly increased in the tibialis anterior muscle with 3 days of hindlimb suspension and significantly decreased in response to 2 days of food deprivation.
products of Bmp1 (zeige BMP1 Antikörper) and Tll1 are responsible for in vivo cleavage of Chordin (zeige CHRD Antikörper) in mammals
The results show that Nkx2-5 (zeige NKX2-5 Antikörper) is a direct activator of Tll-1 expression and provide insight into the mechanism of the defects found in both the Tll-1 and Nkx2-5 (zeige NKX2-5 Antikörper) knockout mice.
Multivariate analysis showed rs17047200 AT/TT to be an independent risk factor for HCC (zeige FAM126A Antikörper) (hazard ratio, 1.78; P = .008).
This SNP [TLL1 gene ]could not be confirmed as a risk factor for CHD (zeige CHDH Antikörper) [coronary heart disease]in T2DM [type-2 Diabetes mellitus]patients
This study identified TLL1 as a new susceptibility gene for PTSD.
TLL-1 gene mutation with an insertion mutation of base A in exon 10 is common in Chinese patients with sporadic congenital heart diseases.
We identified a variant in a single PPAR (zeige PPARA Antikörper) pathway gene, TLL1, that is associated with the extent of coronary artery disease independently of clinical predictors, specifically in patients with type 2 diabetes mellitus.
Data demonstrate that TLL-1, which has intermediate activity, forms a calcium-ion dependent dimer with monomers stacked side-by-side.
tolloid-like 1 binds procollagen C-proteinase enhancer protein (zeige PCOLCE Antikörper) 1 and differs from bone morphogenetic protein 1 (zeige BMP1 Antikörper) in the functional roles of homologous protein domains
The crystal structures of the protease domains of human BMP-1 (zeige BMP1 Antikörper) and the closely related Tolloid-like protease 1 (TLL-1), are reported.
Mutations in mammalian tolloid-like 1 gene detected in adult patients with Atrial septal defect
These results indicate that the hypoxia responsive motif is directly involved in the activation of the mTll (zeige NR2E1 Antikörper)-1 transcription under hypoxic conditions.
Acts specifically in the ventral tail bud during a approximately 4 h period extending from the completion of gastrulation to early somitogenesis stages to regulate bone morphogenetic protein signaling.
bmp1 (zeige BMP1 Antikörper) and mfn (tll1) gene products functionally overlap and are together responsible for a key portion of the chordin (zeige CHRD Antikörper) processing activity necessary to formation of the zebrafish dorsoventral axis.
Szl negatively regulates Tll (zeige NR2E1 Antikörper) activity to control deposition of a fibronectin (FN (zeige FN1 Antikörper)) matrix between the mesoderm and endoderm, which is required to maintain BMP signaling
This gene encodes an astacin-like, zinc-dependent, metalloprotease that belongs to the peptidase M12A family. This protease processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Studies in mice suggest that this gene plays multiple roles in the development of mammalian heart, and is essential for the formation of the interventricular septum. Allelic variants of this gene are associated with atrial septal defect type 6. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, tolloid-like protein 1
, chicken tolloid-like protein 1
, colloid protein
, metalloprotease colloid
, tolloid-like 2
, dorsal-ventral patterning tolloid-like protein 1
, mini fin protein
, xenopus tolloid-like protein 1
, xolloid-like metalloprotease