Tissue Factor Pathway Inhibitor 2 (TFPI2) ELISA Kits

Zebrafish Tissue Factor Pathway Inhibitor 2 (TFPI2) Interaktionspartner

1. Taken together, these results demonstrated a critical role of zTfpi-2 during embryonic cardiac development, as well as an important regulator of hematopoiesis.

2. zTfpi2 is involved in zebrafish central nervous system development

Human Tissue Factor Pathway Inhibitor 2 (TFPI2) Interaktionspartner

1. TFPI-2 role in the proliferation and invasion of breast cancer cells.Translocation of TFPI-2 into nucleus affects the promoter activity of the MMP-2 gene.TFPI-2 suppresses breast cancer cell invasion through the regulation of MMP-2 gene expression.

2. Mono-ADP-ribosylation of H3R117 upregulated methylation of TFPI2 by impact TET1.

3. investigated association between 4 SNPs within TFPI-2 gene and coronary atherosclerosis risk in Chinese Han

4. Proliferation, mRNA level of tissue factor pathway inhibitor 2 (TFPI2), and cell invasion were evaluated using anti-Ki-67 antibody staining, reverse transcriptase-polymerase chain reaction and xCELLigence system.

5. These results suggest that LSD2 achieves a promoting effect on small cell lung cancer by indirectly regulating TFPI2 expression through the mediation of DNMT3B expression or through the regulation of the demethylation of H3K4me1 in the promoter region of the TFPI2 gene.

6. MiR-616-3p binds specifically to the 3'-UTR region of TFPI2 mRNA.

7. Tissue factor pathway Inhibitor 2 potencies differ between antifibrinolytic agents against human and mouse enzymes plasmin, factor XIa, and kallikrein

8. estrogen induced TFPI-2 expression in MCF7 cells is mediated by ERalpha and also by the action of LSD1.

9. TFPI2 hypermethylation is associated with colorectal cancer.

10. our research indicated that miR-130a functions as an oncogene by targeting TFPI2, miR-130a inhibition reduced the growth and angiogenesis of hemangioma by inactivating the FAK/PI3K/Rac1/mdm2 pathway

11. TFPI-2 expression was decreased in bladder cancer. TFPI-2 expression was decreased with progression in tumor grade and stage and was correlated to decreased apoptosis.

12. TFPI2 is a useful serum biomarker for preoperative clinical diagnosis of CCC.

13. This TPR-dependent PP5 inhibition shown by Ro 90-7501 is a unique and novel inhibitory mechanism, which might be a useful tool for studies of PP5 on both regulatory mechanism and drug discovery.

14. Over-expression of TFPI-2 and aberrant promoter methylation status presented in the preeclampsia placentas, suggesting that epigenetic mechanism might contribute to the pathogenesis of preeclampsia.

15. Its methylation is a prognostic biomarker for hepatocellular carcinoma after hepatectomy.

16. Data show that silencing tumor-endothelial cells (EC) for trypsinogen 4 accumulated tissue factor pathway inhibitor-2 (TFPI-2) in the matrix.

17. Hypermethylation of TFPI2 promoter is increased in inflamed colon tissue.

18. DNA methylation of TFPI2 may play an important role in the carcinogenesis of cervical cancer and that the differential methylation of TFPI2 may at least partially explain the disparity in cervical cancer incidence between Uygur and Han women.

19. our findings suggested that the differential expression of MMP-2 and TFPI-2 have a negative correlation in pancreatic carcinoma

20. Our finding suggests that the decreased expression of TFPI-2 may play an important role in the carcinogenesis and progression, and may become a new adjunct marker in the diagnosis and prognosis in cholangiocarcinoma

Mouse (Murine) Tissue Factor Pathway Inhibitor 2 (TFPI2) Interaktionspartner

1. Tissue factor pathway Inhibitor 2 potencies differ between antifibrinolytic agents against human and mouse enzymes plasmin, factor XIa, and kallikrein

2. A novel mouse model is presented and can be used to investigate the role of TFPI-2 in the process of atherosclerosis.

3. Over-expression of TFPI-2 promotes atherosclerotic plaque stability, which may be related to inhibition of matrix metalloproteinases.

4. Bovine TFPI2 was compared to mouse TFPI2.

5. human and murine TFPI-2 have different functions in liver regulation during inflammation in the two species

6. Our data suggest that TFPI-2 may be an important regulator of aberrant angiogenesis associated with tumor growth/metastasis, cardiovascular diseases, chronic inflammation, or diabetes.

7. Deficiency for the histone methyltransferase EHMT2 or for the Polycomb group protein EED, leads to biallelic expression of Tfpi2 in the extra-embryonic lineages, whereas the other genes in the cluster maintain correct imprinting.

8. Dynamic changes of Tfpi2 associated with Il-1beta and Tnf-alpha in the development of acute lung injury are reported.

Cow (Bovine) Tissue Factor Pathway Inhibitor 2 (TFPI2) Interaktionspartner

1. Bovine TFPI2 was cloned and its expression and characterization determined.