Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) Proteine (TFPI)

TFPI encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. Zusätzlich bieten wir Ihnen TFPI Antikörper (205) und TFPI Kits (98) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TFPI 7035 P10646
TFPI 21788 O54819
TFPI 29436 Q02445
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Top TFPI Proteine auf antikoerper-online.de

Showing 10 out of 34 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Human Cells Human His tag 10 μg Anmelden zum Anzeigen 20 bis 21 Tage
$250.80
Details
Human Cells Maus His tag 10 μg Anmelden zum Anzeigen 20 bis 21 Tage
$250.80
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
HEK-293 Cells Human His tag 10 μg Anmelden zum Anzeigen 2 bis 3 Tage
$205.00
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Escherichia coli (E. coli) Human GST tag Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI) (AA 29-280), (partial) protein (GST tag) 50 μg Anmelden zum Anzeigen 13 bis 16 Tage
$242.00
Details
Escherichia coli (E. coli) Human His tag,GST tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$672.00
Details
HEK-293 Cells Human Biotin,His tag Biotinylated Human TFPI on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%. 200 μg Anmelden zum Anzeigen 2 bis 3 Tage
$1,375.00
Details
Escherichia coli (E. coli) Kaninchen His tag,GST tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$736.00
Details
Hefe Kaninchen His tag Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI) (AA 25-300) protein (His tag) 500 μg Anmelden zum Anzeigen 60 bis 71 Tage
$1,155.00
Details

TFPI Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , ,
, , , ,
Mouse (Murine) , ,

Rat (Rattus)

Am meisten referenzierte TFPI Proteine

  1. Human TFPI Protein expressed in Escherichia coli (E. coli) - ABIN2123670 : Ranasinghe, Duke, Harvie, McManus: Kunitz-type protease inhibitor as a vaccine candidate against schistosomiasis mansoni. in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2017 (PubMed)

  2. Human TFPI Protein expressed in Human Cells - ABIN2003062 : Broze, Warren, Novotny, Higuchi, Girard, Miletich: The lipoprotein-associated coagulation inhibitor that inhibits the factor VII-tissue factor complex also inhibits factor Xa: insight into its possible mechanism of action. in Blood 1988 (PubMed)
    Show all 5 Pubmed References

  3. Human TFPI Protein expressed in Escherichia coli (E. coli) - ABIN1080946 : Gamperl, Plattfaut, Freund, Quecke, Theophil, Gieseler: Extracellular vesicles from malignant effusions induce tumor cell migration: inhibitory effect of LMWH tinzaparin. in Cell biology international 2016 (PubMed)

Weitere Proteine zu Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI) Interaktionspartnern

Human Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI) Interaktionspartner

  1. Patients with early onset preeclampsia are characterised by an attenuated coagulation response characterised by reduced thrombin (zeige F2 Proteine) generation stimulated by low-dose TF and elevated plasma TFPI activity.

  2. Developed functional protein S assays that measure both the activated protein C (zeige PROC Proteine)- and TFPI-cofactor activities of protein S in plasma, which are hardly if at all affected by the FV Leiden mutation.

  3. These data indicate that both isoforms of TFPI are present in advanced plaques and that anti-inflammatory M2 macrophages may be a potential source of TFPI.

  4. Among the various candidate genes involved in acute rejection, CD47 (zeige CD47 Proteine) inhibits monocyte/macrophage-mediated phagocytosis by identifying the CD47 (zeige CD47 Proteine) signal regulatory protein alpha (SIRP (zeige SIRPA Proteine)-alpha) as self/non-self. Tissue factor pathway inhibitor (TFPI) is involved in the regulation of the coagulation pathway and is able to bind to another ligand of CD47 (zeige CD47 Proteine), thrombospondin-1 (TSP-1 (zeige THBS1 Proteine)).

  5. Tissue Factor Pathway Inhibitor Gene Polymorphism is associated with response to therapy in Colorectal Cancer.

  6. For the first time, we show that a TFPI variant is significantly associated with fibrinogen levels and risk of coronary artery disease.

  7. miR (zeige MLXIP Proteine)-27a/b and miR (zeige MLXIP Proteine)-494 regulate TFPIalpha expression; there may be a role of these miRNAs in the estrogen-mediated downregulation of TFPIalpha

  8. Genetic variations of the TFPI genes seem to be related with coronary artery disease, which likely cooperate with metabolic risk factor (diabetes mellitus) and play critical roles in the pathogenesis of coronary artery disease in Han Chinese.

  9. Cleavage of FV at Arg(1545) , which abolishes the anticoagulant properties of FV and commits FV to the procoagulant pathway, is inhibited by binding of the TFPIalpha C-terminus to the FV acidic region

  10. The aim of this study was to evaluate the concentration of TF and its inhibitor TFPI in blood plasma, the impact of traditional and non-traditional cardiovascular risk factors on their concentration and the impact of both markers of haemostasis on the severity of subclinical atherosclerosis.

Mouse (Murine) Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI) Interaktionspartner

  1. endogenous TFPI from vascular smooth muscle cells inhibited ferric chloride-induced arterial thrombosis without causing hemostatic effects

  2. TFPI-1 interacts with AMOT (zeige AMOT Proteine), which led to a decrease in the phosphorylation of YAP (zeige YAP1 Proteine) and further increased the genes expression of the proliferation and migration involved. Our results further confirmed that atherosclerosis was a localized disease.

  3. Results suggest that endothelial cell-anchored TFPI controls lung tumor metastasis, and does so largely through the inhibition of local TF-induced thrombin (zeige F2 Proteine) generation and the regulation of the lung microenvironment in mice.

  4. Data argue against an important role for endogenous TFPI in the antibacterial, inflammatory and procoagulant response during pneumococcal pneumonia.

  5. TFPI has an anti-proliferative role in TNF-alpha (zeige TNF Proteine) stimulated-VSMCs at least partly by interfering with the MCP-3 (zeige CCL7 Proteine)/CCR2 (zeige CCR2 Proteine) pathway and then via suppression of the ERK1/2 and PI3K/AKT (zeige AKT1 Proteine) signaling pathways

  6. Results demonstrate that TFPI physiologically modulates thrombin (zeige F2 Proteine)-dependent platelet activation in a manner that is required for successful embryonic development

  7. Tissue factor (zeige F3 Proteine) plays a hitherto unreported role in the generation of macrophage migratory inhibitory factor by vascular smooth muscle cells in atherosclerosis-prone ApoE (zeige APOE Proteine)(-/-) mice.

  8. The increased plasmin (zeige PLG Proteine) generation during the early stages of sepsis could cleave/inactivate TFPI and thus lead to thrombotic complications.

  9. structural features within residues of the 39-loop contribute to the resistance of FIXa (zeige ETFB Proteine) to inhibition by plasma inhibitors ZPI (zeige SERPINA10 Proteine) and TFPI.

  10. PAK1 (zeige PAK1 Proteine) negatively regulates the expression of TFPI and additionally contributes to increased TF activity.

Rabbit Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI) Interaktionspartner

  1. Upregulated TF expression and increased plasma TF level during reperfusion period, reduced plasma TFPI-1 level during reperfusion period.

Cow (Bovine) Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI) Interaktionspartner

  1. structural features within residues of the 39-loop contribute to the resistance of FIXa (zeige ETFB Proteine) to inhibition by plasma inhibitors ZPI (zeige SERPINA10 Proteine) and TFPI.

TFPI Protein Überblick

Protein Überblick

This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed.

Genbezeichner und Symbole assoziert mit TFPI

  • tissue factor pathway inhibitor (TFPI)
  • tissue factor pathway inhibitor (Tfpi)
  • tissue factor pathway inhibitor a (tfpia)
  • A630013F22Rik Protein
  • AW552122 Protein
  • EPI Protein
  • LACI Protein
  • si:dz44f8.1 Protein
  • TFI Protein
  • TFPI Protein
  • TFPI1 Protein
  • tfpib Protein
  • wu:fb92g01 Protein
  • zgc:152844 Protein
  • zgc:158592 Protein

Bezeichner auf Proteinebene für TFPI

anti-convertin , extrinsic pathway inhibitor , tissue factor pathway inhibitor , lipoprotein-associated coagulation inhibitor , EPI , LACI , uncharacterized protein LOC100155068 , LOW QUALITY PROTEIN: tissue factor pathway inhibitor , coagulation inhibitor , lipoprotein-associated , tissue factor pathway inhibitor b

GENE ID SPEZIES
7035 Homo sapiens
21788 Mus musculus
29436 Rattus norvegicus
403921 Canis lupus familiaris
613026 Macaca mulatta
100009401 Oryctolagus cuniculus
423989 Gallus gallus
508763 Bos taurus
100155068 Sus scrofa
101120391 Ovis aries
100727170 Cavia porcellus
359833 Danio rerio
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