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TRIP11 was identified based on the interaction of its protein product with thyroid hormone receptor beta. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.
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Decreased expressions of TRIP11, THRA (zeige THRA Antikörper), and THRB (zeige THRB Antikörper) correlated with poor survival of renal cell cancer patients. Expressions of TRIP11 and HIF-1beta (zeige ARNT Antikörper) correlated with tumor grades.
The authors conclude that the Golgi uses GMAP-210 as a filter to select transport vesicles according to their size and bulk lipid composition.
role for GMAP-210 in several trafficking steps at the ER-Golgi interface
GMAP-210 has a role for membrane tethering in maintaining Golgi structure and a role for Rab2 (zeige RAB2A Antikörper) binding in linking tethering with downstream docking and fusion events at the Golgi apparatus.
Rb is present in HIF1alpha (zeige HIF1A Antikörper)-ARNT/HIF1beta (zeige ARNT Antikörper) transcriptional complexes associated with TRIP230 as determined by co-immuno-precipitation, GST (zeige SLCO6A1 Antikörper)-pull-down and ChIP assays
identification of a mutation affecting GMAP-210 in mice, and then in humans, as the cause of a lethal skeletal dysplasia
demonstrate that the thyroid hormone receptor (zeige THRA Antikörper)/retinoblastoma-interacting protein 230 (TRIP230) interacts directly with aryl hydrocarbon receptor nuclear translocator(ARNT (zeige ARNT Antikörper)) and is essential for both hypoxic and TCDD-mediated transcriptional responses
the attachment of golgin GMAP-210 to lipid membranes
Localisation of GMAP-210 (TRIP11) to Golgi is the result of the combined action of two domains (N- and C-terminal) that recognize different sub-regions of the Golgi apparatus.
Data show that IFT88 (zeige IFT88 Antikörper) is present in the Golgi of spermatids, that the microtubule-associated golgin GMAP210 and IFT88 (zeige IFT88 Antikörper) participate in acrosome, HTCA, and tail biogenesis.
mice with lethal skeletal dysplasia had a nonsense mutation in the thyroid hormone receptor interactor 11 gene (Trip11), which encodes the Golgi microtubule-associated protein (zeige SPAG5 Antikörper) 210 (GMAP-210)
GMAP210 and IFT20 (zeige IFT20 Antikörper) function together at the Golgi in the sorting of proteins destined for the ciliary membrane.
This gene was identified based on the interaction of its protein product with thyroid hormone receptor beta. This protein is associated with the Golgi apparatus. The N-terminal region of the protein binds Golgi membranes and the C-terminal region binds the minus ends of microtubules\\\\; thus, the protein is thought to play a role in assembly and maintenance of the Golgi ribbon structure around the centrosome. Mutations in this gene cause achondrogenesis type IA.
Golgi-microtubule-associated protein of 210 kDa
, TR-interacting protein 11
, clonal evolution-related gene on chromosome 14 protein
, golgi-associated microtubule-binding protein 210
, thyroid receptor-interacting protein 11
, thyroid hormone receptor interactor 11
, thyroid receptor-interacting protein 11-like