Thrombospondin 2 Proteine (THBS2)

The protein encoded by THBS2 belongs to the thrombospondin family. Zusätzlich bieten wir Ihnen Thrombospondin 2 Antikörper (74) und Thrombospondin 2 Kits (44) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
THBS2 7058 P35442
THBS2 21826 Q03350
THBS2 292406  
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Showing 8 out of 8 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
Escherichia coli (E. coli) Maus His tag,GST tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Escherichia coli (E. coli) Ratte His tag,GST tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Escherichia coli (E. coli) Maus His tag   50 μg Anmelden zum Anzeigen 11 Days
Hefe Maus His tag   50 μg Anmelden zum Anzeigen 8 bis 11 Tage
Escherichia coli (E. coli) Human T7 tag,His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Escherichia coli (E. coli) Maus Unkonjugiert   100 μg Anmelden zum Anzeigen 11 bis 18 Tage

THBS2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
Mouse (Murine) , ,
Rat (Rattus)

Weitere Proteine zu Thrombospondin 2 (THBS2) Interaktionspartnern

Horse (Equine) Thrombospondin 2 (THBS2) Interaktionspartner

  1. data suggest that THBS2 might modulate angiogenesis during wound healing in the horse, which could protect against the disproportionate fibroplasia commonly afflicting limb wounds and leading to the development of exuberant granulation tissue

Human Thrombospondin 2 (THBS2) Interaktionspartner

  1. TSP-2 enhances the migration of PCa (zeige FLVCR1 Proteine) cells by increasing MMP-2 (zeige MMP2 Proteine) expression through down-regulation of miR (zeige MLXIP Proteine)-376c expression.

  2. we report microRNA-135b (miR (zeige MLXIP Proteine)-135b), a key regulator of the malignancy, highly expressed in the RC component and promoting MLS cell invasion in vitro and metastasis in vivo through the direct suppression of thrombospondin 2 (THBS2).

  3. High THBS2 expression is associated with lung cancer.

  4. STMN1 (zeige STMN1 Proteine),COF1 (zeige CFL1 Proteine) and PAIRBP1 (zeige SERBP1 Proteine) thus represent proteins associated with proliferative and aggressive tumors of high grades, while TSP2 and POSTN (zeige POSTN Proteine) were connected to low grade tumors with better prognosis

  5. the tissue levels of THBS2 and LECT-2 (zeige LECT2 Proteine) may correlate with the stage of atherosclerosis.

  6. THBS2 and THBS4 (zeige THBS4 Proteine) mRNA are overexpressed in gastric cancer in a Southeast Chinese population.

  7. THBS2, but not COL1A2 (zeige COL1A2 Proteine) and SPP1 (zeige SPP1 Proteine), may serve as an indicator of gastric cancer prognosis.

  8. The level of THBS2 in differentiating stem cells, influences chondrogenic differentiation potential.

  9. THBS2 protein, human is predicting lymph node metastases in OSCC, overall survival and disease-free survival.

  10. Study suggests THBS2 is aberrantly expressed in gastric cancer and plays a critical role in cancer progression.

Cow (Bovine) Thrombospondin 2 (THBS2) Interaktionspartner

  1. Data suggest THBS1 (zeige THBS1 Proteine) expression predominates in luteal endothelial cells; THBS2 expression predominates in luteinized granulosa cells. Luteinization down-regulates expression of THBS1 (zeige THBS1 Proteine)/THBS2, up-regulates expression of FGF2 (fibroblast growth factor 2 (zeige FGF2 Proteine)).

  2. TSP-1 and -2 were coordinately expressed in the extravascular compartment of the ovary during early follicle development. VEGF was inversely expressed, with expression increasing as follicles developed.

Mouse (Murine) Thrombospondin 2 (THBS2) Interaktionspartner

  1. TSP2 deficiency imparted a brittle phenotype on cortical bone. electron microscopy revealed less intensely stained collagen fibrils with altered morphology in the extracellular matrix assembled by osteoblasts on the anterior surface of TSP2-KO femora.

  2. Enhanced levels of TSP-2 in the skin result in reduced susceptibility to chemically-induced skin carcinogenesis.

  3. in the context of osteoblast differentiation, TSP2 promotes the assembly of a type-I collagen-rich matrix by facilitating pro-collagen processing.

  4. The proposed mechanism for the shift in stem cell fate in fracture healing is that increased vascular density and hence oxygen availability in TSP2-null mice regulates differentiation.

  5. The upregulation of TSP-2 mediated by increased oxidative stress contributes to angiogenesis dysfunction in diabetic bone marrow derived angiogenic cells.

  6. TSP2 is a negative regulator of ischemic fracture healing, and in the absence of TSP2 bone regeneration is enhanced.

  7. Using a TSP-2-knockout mouse model and cardiac cell transplantation, we found significantly reduced fibrosis and increased endothelial cell density in the peri (zeige POSTN Proteine)-graft region.

  8. TSP1 (zeige GZMA Proteine)-null and TSP2-null mice have lower IOPs than their WT counterparts. The rate of aqueous turnover suggests that the mechanism is enhanced outflow facility.

  9. the two TSP2 isforms are differentially modulated at injured and noninjured skeletal sites in an animal undergoing fracture healing.

  10. TSP-2 has a protective role against cardiac inflammation, injury, and dysfunction in acute viral myocarditis.

Thrombospondin 2 (THBS2) Protein Überblick

Protein Überblick

The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angiogenesis. Studies of the mouse counterpart suggest that this protein may modulate the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration.

Genbezeichner und Symbole assoziert mit Thrombospondin 2 Proteine (THBS2)

  • thrombospondin 2 (THBS2)
  • thrombospondin 2 L homeolog (thbs2.L)
  • thrombospondin 2a (thbs2a)
  • thrombospondin 2 (Thbs2)
  • Thbs-2 Protein
  • THBS1 Protein
  • thbs2 Protein
  • TMEM200A Protein
  • TSP-2 Protein
  • TSP2 Protein

Bezeichner auf Proteinebene für Thrombospondin 2 Proteine (THBS2)

thrombospondin-2 , thrombospondin 2 , Tsp-2 , CISP , corticotropin-induced secreted protein , transmembrane protein 200A

484087 Canis lupus familiaris
100050044 Equus caballus
708165 Macaca mulatta
779026 Xenopus laevis
794881 Danio rerio
100221289 Taeniopygia guttata
7058 Homo sapiens
338092 Bos taurus
21826 Mus musculus
414837 Gallus gallus
292406 Rattus norvegicus
100357972 Oryctolagus cuniculus
100735538 Cavia porcellus
100153940 Sus scrofa
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