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The protein encoded by THBS2 belongs to the thrombospondin family. Zusätzlich bieten wir Ihnen Thrombospondin 2 Antikörper (83) und Thrombospondin 2 Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.
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Rat (Rattus) Thrombospondin 2 ELISA Kit für Sandwich ELISA - ABIN433960
Kim, Kim, Park, Kim: The wound healing effects of vitamin A eye drops after a corneal alkali burn in rats. in Acta ophthalmologica 2012
data suggest that THBS2 might modulate angiogenesis during wound healing in the horse, which could protect against the disproportionate fibroplasia commonly afflicting limb wounds and leading to the development of exuberant granulation tissue
TWIST2 induces miR (zeige MLXIP ELISA Kits)-221-3p expression and consequently suppresses its direct target, THBS2, in lymphatic metastasis cervical cancer.
THBS2 could be considered as a novel prognostic marker in colorectal cancer.
By testing for THBS2 and another marker, CA19-9, researchers identified blood samples from patients with the disease with 98% specificity and 87% sensitivity.
the combination of THBS2 and CA19-9 yielded a sensitivity of 87% for pancreatic ductal adenocarcinoma in the phase 2b study.
Study found that 2 single nucleotide polymorphisms (rs6422747 and rs6422748) in the THBS2 gene were associated with susceptibility of intervertebral disc degeneration (IDD) but not severity of IDD in a Chinese Han population; results indicated that THBS2 gene polymorphisms might be the risk factors for IDD.
TSP-2 enhances the migration of PCa cells by increasing MMP-2 (zeige MMP2 ELISA Kits) expression through down-regulation of miR (zeige MLXIP ELISA Kits)-376c expression.
we report microRNA-135b (miR (zeige MLXIP ELISA Kits)-135b), a key regulator of the malignancy, highly expressed in the RC component and promoting MLS cell invasion in vitro and metastasis in vivo through the direct suppression of thrombospondin 2 (THBS2).
High THBS2 expression is associated with lung cancer.
STMN1 (zeige STMN1 ELISA Kits),COF1 (zeige CFL1 ELISA Kits) and PAIRBP1 (zeige SERBP1 ELISA Kits) thus represent proteins associated with proliferative and aggressive tumors of high grades, while TSP2 and POSTN (zeige POSTN ELISA Kits) were connected to low grade tumors with better prognosis
the tissue levels of THBS2 and LECT-2 (zeige LECT2 ELISA Kits) may correlate with the stage of atherosclerosis.
Data suggest THBS1 (zeige THBS1 ELISA Kits) expression predominates in luteal endothelial cells; THBS2 expression predominates in luteinized granulosa cells. Luteinization down-regulates expression of THBS1 (zeige THBS1 ELISA Kits)/THBS2, up-regulates expression of FGF2 (fibroblast growth factor 2 (zeige FGF2 ELISA Kits)).
TSP-1 (zeige THBS1 ELISA Kits) and -2 were coordinately expressed in the extravascular compartment of the ovary during early follicle development. VEGF (zeige VEGFA ELISA Kits) was inversely expressed, with expression increasing as follicles developed.
TSP2 deficiency imparted a brittle phenotype on cortical bone. electron microscopy revealed less intensely stained collagen fibrils with altered morphology in the extracellular matrix assembled by osteoblasts on the anterior surface of TSP2-KO femora.
Enhanced levels of TSP-2 in the skin result in reduced susceptibility to chemically-induced skin carcinogenesis.
in the context of osteoblast differentiation, TSP2 promotes the assembly of a type-I collagen-rich matrix by facilitating pro-collagen processing.
The proposed mechanism for the shift in stem cell fate in fracture healing is that increased vascular density and hence oxygen availability in TSP2-null mice regulates differentiation.
The upregulation of TSP-2 mediated by increased oxidative stress contributes to angiogenesis dysfunction in diabetic bone marrow derived angiogenic cells.
TSP2 is a negative regulator of ischemic fracture healing, and in the absence of TSP2 bone regeneration is enhanced.
Using a TSP-2-knockout mouse model and cardiac cell transplantation, we found significantly reduced fibrosis and increased endothelial cell density in the peri (zeige POSTN ELISA Kits)-graft region.
TSP1 (zeige GZMA ELISA Kits)-null and TSP2-null mice have lower IOPs than their WT counterparts. The rate of aqueous turnover suggests that the mechanism is enhanced outflow facility.
the two TSP2 isforms are differentially modulated at injured and noninjured skeletal sites in an animal undergoing fracture healing.
The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angiogenesis. Studies of the mouse counterpart suggest that this protein may modulate the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration.
, thrombospondin 2
, corticotropin-induced secreted protein
, transmembrane protein 200A