anti-Thrombospondin 2 (THBS2) Antikörper

The protein encoded by THBS2 belongs to the thrombospondin family. Zusätzlich bieten wir Ihnen Thrombospondin 2 Kits (34) und Thrombospondin 2 Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
THBS2 7058 P35442
THBS2 21826 Q03350
THBS2 292406  
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Top anti-Thrombospondin 2 Antikörper auf

Showing 10 out of 79 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Huhn Kaninchen Unkonjugiert WB Western blot analysis of Thrombospondin 2 expression in A549 (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL 13 bis 14 Tage
Human Kaninchen Unkonjugiert IHC (p), WB Anti-Thrombospondin 2 antibody, IHC(P) IHC(P): Human Placenta Tissue Anti-Thrombospondin 2 antibody, Western blotting All lanes: Anti THBS2  at 0.5ug/ml Lane 1: SMMC Whole Cell Lysate at 40ug Lane 2: MCF-7 Whole Cell Lysate at 40ug Lane 3:  Whole Cell Lysate at 40ug Lane 4: JURKAT Whole Cell Lysate at 40ug Lane 5: NIH 3T3 Whole Cell Lysate at 40ug Predicted bind size: 130KD Observed bind size: 130KD 100 μg 4 bis 6 Tage
Human Kaninchen Unkonjugiert ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg 13 bis 16 Tage
Maus Kaninchen Unkonjugiert ICC, IHC, WB DAB staining on IHC-P; Samples: Mouse Pancreas Tissue 100 μg 13 bis 16 Tage
Human Kaninchen Unkonjugiert ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Rat Testis, antibody was diluted at 1:100. Western Blot (WB) analysis of Mouse Heart lysis using THBS2 antibody. 100 μL Verfügbar
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of various cells, using THBS2 antibody. Immunohistochemistry of paraffin-embedded human stomach using THBS2 antibody at dilution of 1:100 (x40 lens). 100 μL 11 bis 13 Tage
Human Kaninchen Alexa Fluor 350 IF (p)   100 μL 14 bis 21 Tage
Human Kaninchen Cy5 IF (p)   100 μL 14 bis 21 Tage
Human Kaninchen Alexa Fluor 488 IF (p)   100 μL 14 bis 21 Tage
Human Kaninchen Cy5.5 IF (p)   100 μL 14 bis 21 Tage

Am meisten referenzierte anti-Thrombospondin 2 Antikörper

  1. Human Polyclonal Thrombospondin 2 Primary Antibody für IF (p), IHC (p) - ABIN872994 : Chen, Yao, Zhao, He, Ding, Li, Long: MiR-1246 promotes SiHa cervical cancer cell proliferation, invasion, and migration through suppression of its target gene thrombospondin 2. in Archives of gynecology and obstetrics 2014 (PubMed)

Weitere Antikörper gegen Thrombospondin 2 Interaktionspartner

Horse (Equine) Thrombospondin 2 (THBS2) Interaktionspartner

  1. data suggest that THBS2 might modulate angiogenesis during wound healing in the horse, which could protect against the disproportionate fibroplasia commonly afflicting limb wounds and leading to the development of exuberant granulation tissue

Human Thrombospondin 2 (THBS2) Interaktionspartner

  1. High THBS2 expression is associated with colorectal cancer.

  2. High TSP2 expression is associated with Pancreatic Cancer.

  3. the pathological roles of 4N1K-peptide are different from those of TSP-2, and 4N1K-peptide would be a more useful predictive marker and potential therapeutic target compared to TSP-1 and TSP-2 in patients with Bladder Cancer

  4. Collectively, our data disclosed that the downregulation of miR-20a triggered reduced proliferation, decreased autophagy and increased apoptosis by targeting THBS2 in cervical cancer (CC) cells, deepening our understanding on etiology of CC and providing some candidate targets for the therapy of CC.

  5. TSP-2 expression was associated with MMP-13 expression and poor prognosis in lung cancer.

  6. This study demonstrates that COL1A2, COL6A3, and THBS2 gene silencing inhibits gastric cancer cell proliferation, migration, and invasion while promoting apoptosis through the PI3K-Akt signaling pathway.

  7. Data revealed a particularly high expression of a short TSP2 transcript containing only the last 9 (3') exons of the full-length TSP2 transcript. It lacked the anti-angiogenic thrombospondin type 1 repeats domain. The study proposes that sTSP2 expressed by tumor-associated vessels might compete with stromal TSP2 for binding to anti-angiogenic receptors and thus diminish the anti-angiogenic effects of TSP2.

  8. TWIST2 induces miR-221-3p expression and consequently suppresses its direct target, THBS2, in lymphatic metastasis cervical cancer.

  9. THBS2 could be considered as a novel prognostic marker in colorectal cancer.

  10. By testing for THBS2 and another marker, CA19-9, researchers identified blood samples from patients with the disease with 98% specificity and 87% sensitivity.

  11. the combination of THBS2 and CA19-9 yielded a sensitivity of 87% for pancreatic ductal adenocarcinoma in the phase 2b study.

  12. Study found that 2 single nucleotide polymorphisms (rs6422747 and rs6422748) in the THBS2 gene were associated with susceptibility of intervertebral disc degeneration (IDD) but not severity of IDD in a Chinese Han population; results indicated that THBS2 gene polymorphisms might be the risk factors for IDD.

  13. TSP-2 enhances the migration of PCa cells by increasing MMP-2 expression through down-regulation of miR-376c expression.

  14. we report microRNA-135b (miR-135b), a key regulator of the malignancy, highly expressed in the RC component and promoting MLS cell invasion in vitro and metastasis in vivo through the direct suppression of thrombospondin 2 (THBS2).

  15. High THBS2 expression is associated with lung cancer.

  16. STMN1,COF1 and PAIRBP1 thus represent proteins associated with proliferative and aggressive tumors of high grades, while TSP2 and POSTN were connected to low grade tumors with better prognosis

  17. the tissue levels of THBS2 and LECT-2 may correlate with the stage of atherosclerosis.

  18. THBS2 and THBS4 mRNA are overexpressed in gastric cancer in a Southeast Chinese population.

  19. THBS2, but not COL1A2 and SPP1, may serve as an indicator of gastric cancer prognosis.

  20. The level of THBS2 in differentiating stem cells, influences chondrogenic differentiation potential.

Cow (Bovine) Thrombospondin 2 (THBS2) Interaktionspartner

  1. temporal expression and localization pattern of the thrombospondins and their specific receptors in the antral follicles and corpora lutea during the different physiological phases of the estrous cycle and induced luteolysis appear to be compatible with their inhibitory role in the control of ovarian angiogenesis

  2. Data suggest THBS1 expression predominates in luteal endothelial cells; THBS2 expression predominates in luteinized granulosa cells. Luteinization down-regulates expression of THBS1/THBS2, up-regulates expression of FGF2 (fibroblast growth factor 2).

  3. TSP-1 and -2 were coordinately expressed in the extravascular compartment of the ovary during early follicle development. VEGF was inversely expressed, with expression increasing as follicles developed.

Mouse (Murine) Thrombospondin 2 (THBS2) Interaktionspartner

  1. Data provide evidence that TSP2 transcription is suppressed by hypoxia through a mechanism that requires HIF-1alpha.

  2. TWIST2 induces miR-221-3p expression and consequently suppresses its direct target, THBS2, in lymphatic metastasis cervical cancer.

  3. TSP2 deficiency imparted a brittle phenotype on cortical bone. electron microscopy revealed less intensely stained collagen fibrils with altered morphology in the extracellular matrix assembled by osteoblasts on the anterior surface of TSP2-KO femora.

  4. Enhanced levels of TSP-2 in the skin result in reduced susceptibility to chemically-induced skin carcinogenesis.

  5. in the context of osteoblast differentiation, TSP2 promotes the assembly of a type-I collagen-rich matrix by facilitating pro-collagen processing.

  6. The proposed mechanism for the shift in stem cell fate in fracture healing is that increased vascular density and hence oxygen availability in TSP2-null mice regulates differentiation.

  7. The upregulation of TSP-2 mediated by increased oxidative stress contributes to angiogenesis dysfunction in diabetic bone marrow derived angiogenic cells.

  8. TSP2 is a negative regulator of ischemic fracture healing, and in the absence of TSP2 bone regeneration is enhanced.

  9. Using a TSP-2-knockout mouse model and cardiac cell transplantation, we found significantly reduced fibrosis and increased endothelial cell density in the peri-graft region.

  10. TSP1-null and TSP2-null mice have lower IOPs than their WT counterparts. The rate of aqueous turnover suggests that the mechanism is enhanced outflow facility.

  11. the two TSP2 isforms are differentially modulated at injured and noninjured skeletal sites in an animal undergoing fracture healing.

  12. TSP-2 has a protective role against cardiac inflammation, injury, and dysfunction in acute viral myocarditis.

  13. astrocyte-derived TSP-2 is critical for the maintenance of physiological MMP-2 and MMP-9 levels during the foreign body response and contributes to the repair of the BBB

  14. Endothelial nitric oxide synthase controls the expression of the angiogenesis inhibitor thrombospondin 2

  15. The secreted protein is an autocrine inhibitor of marrow stromal cell proliferation.

  16. Megakaryocytes require this protein for normal platelet formation and function.

  17. Thrombospondin 2 regulates cell proliferation induced by Rac1 redox-dependent signaling

  18. TSP2-null mice provide an animal model to assist in the understanding of the molecular basis of spontaneous, premature softening of the uterine cervix.

  19. Delay in expression of TSP2 and metalloproteinase 2 in the wounds of aged mice could contribute to their impaired rate of wound healing.

  20. CD36 mediates the antiangiogenic effect of thrombospondin-2, which is modulated by histidine-rich glycoprotein

Thrombospondin 2 (THBS2) Antigen-Profil

Protein Überblick

The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angiogenesis. Studies of the mouse counterpart suggest that this protein may modulate the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration.

Genbezeichner und Symbole assoziert mit THBS2

  • thrombospondin 2 (THBS2) Antikörper
  • thrombospondin 2 L homeolog (thbs2.L) Antikörper
  • thrombospondin 2a (thbs2a) Antikörper
  • thrombospondin 2 (Thbs2) Antikörper
  • Thbs-2 Antikörper
  • THBS1 Antikörper
  • thbs2 Antikörper
  • TMEM200A Antikörper
  • TSP-2 Antikörper
  • TSP2 Antikörper

Bezeichner auf Proteinebene für THBS2

thrombospondin-2 , thrombospondin 2 , Tsp-2 , CISP , corticotropin-induced secreted protein , transmembrane protein 200A

484087 Canis lupus familiaris
100050044 Equus caballus
708165 Macaca mulatta
779026 Xenopus laevis
794881 Danio rerio
100221289 Taeniopygia guttata
7058 Homo sapiens
338092 Bos taurus
21826 Mus musculus
414837 Gallus gallus
292406 Rattus norvegicus
100357972 Oryctolagus cuniculus
100735538 Cavia porcellus
100153940 Sus scrofa
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