anti-Tetraspanin 8 (TSPAN8) Antikörper

The protein encoded by TSPAN8 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Zusätzlich bieten wir Ihnen Tetraspanin 8 Proteine (7) und Tetraspanin 8 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TSPAN8 7103 P19075
TSPAN8 216350 Q8R3G9
TSPAN8 171048  
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Top anti-Tetraspanin 8 Antikörper auf

Showing 10 out of 63 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Meerschweinchen Kaninchen Unkonjugiert WB WB Suggested Anti-TSPAN8 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Human brain 100 μL 2 bis 3 Tage
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of Tetraspanin 8 staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Tetraspanin 8 expression in human colon (A), COLO205 (B) whole cell lysates. 200 μL 13 bis 14 Tage
Human Ziege Unkonjugiert ELISA, WB   100 μg 6 bis 7 Tage
Human Kaninchen Unkonjugiert IF, ELISA, WB Western blot analysis of extracts from 293/COLO cells, using TSPAN8 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HeLa cells, using TSPAN8 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 bis 3 Tage
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB 100 μL Verfügbar
Human Ziege Unkonjugiert ELISA, WB 100 μg 11 bis 14 Tage
Human Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
Human Kaninchen Unkonjugiert ELISA, ICC, IF, WB Western blot analysis on Jurkat and K562 cell lysate using TSPAN8 Antibody,The lane on the left is treated with the antigen-specific peptide. ABIN6266740 staining HeLa cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibody. 100 μL 11 bis 12 Tage
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti TM4SF3 Polyclonal Antibody, Unconjugated (ABIN716246) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 3 bis 7 Tage
Human Kaninchen Unkonjugiert WB Tetraspanin 8 antibody used at 1 ug/ml to detect target protein. 50 μg 9 bis 11 Tage

Am meisten referenzierte anti-Tetraspanin 8 Antikörper

  1. Human Monoclonal Tetraspanin 8 Primary Antibody für IF, ELISA - ABIN563195 : Zhou, Ran, Hu, Pan, Li, Chen, Sun, Peng, Zhao, Yu, Sun, Yang: TM4SF3 promotes esophageal carcinoma metastasis via upregulating ADAM12m expression. in Clinical & experimental metastasis 2008 (PubMed)

  2. Human Polyclonal Tetraspanin 8 Primary Antibody für ELISA, WB - ABIN542452 : Grarup, Andersen, Krarup, Albrechtsen, Schmitz, Jørgensen, Borch-Johnsen, Hansen, Pedersen et al.: Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a ... in Diabetes 2008 (PubMed)

  3. Human Polyclonal Tetraspanin 8 Primary Antibody für IF (p), IHC (p) - ABIN716246 : Bhansali, Zhou, Shemshedini: TM4SF3 and AR: A Nuclear Complex that Stabilizes Both Proteins. in Molecular endocrinology (Baltimore, Md.) 2016 (PubMed)

  4. Mouse (Murine) Monoclonal Tetraspanin 8 Primary Antibody für FACS - ABIN4898915 : Fu, Rios, Pal, Law, Jamieson, Liu, Vaillant, Jackling, Liu, Smyth, Lindeman, Ritchie, Visvader: Identification of quiescent and spatially restricted mammary stem cells that are hormone responsive. in Nature cell biology 2017 (PubMed)

Weitere Antikörper gegen Tetraspanin 8 Interaktionspartner

Xenopus laevis Tetraspanin 8 (TSPAN8) Interaktionspartner

  1. overexpression of tm4sf3 promoted development of annular pancreas.

Human Tetraspanin 8 (TSPAN8) Interaktionspartner

  1. These findings reveal a molecular basis of TSPAN8-enhanced Sonic Hedgehog signaling and highlight a role for TSPAN8 in promoting cancer stemness.

  2. High TSPAN8 expression is associated with Drug Resistance in Colorectal Cancer.

  3. miR-324-5p inhibited gastric cancer cell survival by targeting TSPAN8 expression.

  4. TSPAN8 mediated Wnt/beta-catenin pathway through binding to NOTCH2. The role of TSPAN8 in the drug resistance of gastric cancer.

  5. these data point to a crucial role of Co-029 in the modulation of colon cancer cell motility which could be related to the protumoral effect reported for this tetraspanin. Among surface molecules able to mediate Co-029 function, E-cadherin, EGFR and CD44 appear as likely candidates.

  6. Single nucleotide polymorphism in TSPAN8 gene is associated with pathogenesis of bipolar disorder.

  7. Tetraspanin-8 has a role in promoting hepatocellular carcinoma metastasis by increasing ADAM12m expression

  8. LCMR1 modulation was sufficient to positively regulate endogenous Tspan8 expression, with concomitant in vitro phenotypic changes such as loss of melanoma cell-matrix adherence and increase in invasion, and Tspan8 expression promoted tumourigenicity in vivo.

  9. Data indicate a regulatory role for tetraspanin 8 (Tspan8) in melanoma progression by modulating cell-matrix interactions through beta1 integrin - integrin-linked kinase (ILK) axis and establish Tspan8 as a negative regulator of ILK activity.

  10. TSPAN8 might be important for the orchestration of meprin beta at the cell surface with impact on certain proteolytic processes

  11. Knocking down TSPAN8 in AEG-1-overexpressing human hepatocellular carcinoma (HCC) cells markedly inhibited invasion and migration without affecting proliferation. TSPAN8 knockdown profoundly abrogated AEG-1-induced primary tumor and intrahepatic metastasis in an orthopic xenograft model in athymic nude mice

  12. Knockdown and knockout models revealed that CD151 and Tspan8 act as molecular facilitators in wound healing, angiogenesis and tumor progression. [review]

  13. Results provide evidence that TSPAN8 may contribute to the pathogenesis of lung cancer by promoting cell viability and proliferation.

  14. TSPAN8 is involved in tumor progression and is an independent prognostic classifier in patients with gastric cancer.

  15. This novel nuclear localization of TM4SF3 depends on androgen-induced nuclear localization of androgen receptor (AR) in both androgen-dependent and androgen-independent prostate cancer cell lines

  16. Our data suggest that TSPAN8-LEL may play an important role in mCRC cell invasion, and that the antibody we have developed could be a useful tool for inhibiting the invasion of TSPAN8-expressing mCRCs.

  17. Based on nasopharyngeal TSPAN8 gene expression in readily available Nasopharyngeal aspirate samples , we can discriminate between severity of disease in Respiratory syncytial virus infected infants.

  18. Tspn8 was over-expressed in multiple clinical malignant glioma tissues, and its expression level correlated with the grade of tumors.

  19. CO-029 functions as a regulator of both cell-matrix and cell-cell adhesion. During colon cancer progression, CO-029 promotes cancer cell movement by deregulating cell adhesions.

  20. PMA-induced Tspan8-internalization promotes cell migration, but reduces matrix and cell adhesion.

Mouse (Murine) Tetraspanin 8 (TSPAN8) Interaktionspartner

  1. Single nucleotide polymorphism in TSPAN8 gene is associated with pathogenesis of bipolar disorder.

  2. Transplantation studies provided definitive evidence that a TSPAN8-high subpopulation is enriched for spermatogonial stem cells.

  3. results argue for a role for Tspan8 in body-weight regulation in males, but do not show differences in T2D-associated traits that were anticipated from previous human genome-wide association studies.

  4. Results suggest that alterations in gene expression of Gata6, Tspan8, S100a8, and Lmo2 may act via novel pathways that play functionally important roles in Men1-associated tumor progression.

Tetraspanin 8 (TSPAN8) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene.

Genbezeichner und Symbole assoziert mit anti-Tetraspanin 8 (TSPAN8) Antikörper

  • tetraspanin 8 L homeolog (tspan8.L) Antikörper
  • tetraspanin-1 (LOC409511) Antikörper
  • tetraspanin 8 (TSPAN8) Antikörper
  • tetraspanin 8 (tspan8) Antikörper
  • tetraspanin 8 (Tspan8) Antikörper
  • C76990 Antikörper
  • CO-029 Antikörper
  • CO-29 Antikörper
  • E330007O21Rik Antikörper
  • GB13255 Antikörper
  • MGC64550 Antikörper
  • tetraspanin-8 Antikörper
  • Tm4sf3 Antikörper
  • TSPAN-8 Antikörper
  • TSPAN8 Antikörper

Bezeichner auf Proteinebene für anti-Tetraspanin 8 (TSPAN8) Antikörper

tetraspanin 8 , transmembrane 4 superfamily member 3 , tetraspanin-8 , tspan-8 , tumor-associated antigen CO-029 , D6.1A

380553 Xenopus laevis
409511 Apis mellifera
417854 Gallus gallus
496915 Xenopus (Silurana) tropicalis
718622 Macaca mulatta
743174 Pan troglodytes
474448 Canis lupus familiaris
7103 Homo sapiens
216350 Mus musculus
171048 Rattus norvegicus
617508 Bos taurus
100174494 Pongo abelii
Ausgewählte Anbieter für anti-Tetraspanin 8 (TSPAN8) Antikörper
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