Tektin 4 Proteine (TEKT4)

Structural component of ciliary and flagellar microtubules. Zusätzlich bieten wir Ihnen Tektin 4 Antikörper (46) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TEKT4 7184 P14625
TEKT4 71840 Q149S1
TEKT4 302991 Q6AXV2
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
Hefe Xenopus laevis His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage

TEKT4 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu Tektin 4 (TEKT4) Interaktionspartnern

Human Tektin 4 (TEKT4) Interaktionspartner

  1. GRP94 silencing modulates antineoplastic drug resistance of MG63 and 143B cells by inhibiting the induction of apoptosis.

  2. Among infants, an HSP90B1 gene-region variant is associated with BCG-induced IL-2 production and may be associated with protection from TB disease. HSP90B1 knockdown in human monocyte-like cell lines did not influence TLR2 surface localization nor Mtb replication. Together, these data suggest that HSP90B1 regulates T-cell, but not monocyte, responses to mycobacteria in humans.

  3. Our study revealed that TEKT4 shows important biological implications in papillary thyroid cancer

  4. we found that Hsp90beta was positively correlated with vasculogenic mimicry and epithelial-mesenchymal transformation-related proteins in hepatocellular carcinoma

  5. Glucose-regulated protein GRP94 contributes to the development of an aggressive phenotype in breast cancer cells.

  6. Concomitant high expression of ERalpha36, GRP78 and GRP94 is associated with aggressive papillary thyroid cancer behavior and may be used as a predictor for extrathyroid extension, lymph node metastasis, and distant metastasis.

  7. Overexpressed miR-150 attenuates hypoxia-induced human cardiomyocyte cell apoptosis by targeting GRP94.

  8. Regulation of CLC-1 chloride channel biosynthesis by FKBP8 and Hsp90beta as a molecular model for myotonia congenita has been described.

  9. Study demonstrated that the lack of gp96 in both the human monocytic cell line MM6 and in macrophages from LysMcre-gp96 floxed mice neither leads to a complete loss of TLR 2 expression nor to a complete loss of TLR-induced signaling, but is associated with an impaired phosphorylation of ERK and p38. These results reveal for the first time a crucial role for gp96 in the regulation of ERK and p38 kinases.

  10. HSP-gp96 promotes T cell response, enhances DC antigen presentation and induces cytokine secretion in human gastric cancer cell lines.

  11. our results besides adding further evidence in support of Grp94 as the shared tumor antigen in tumors of the GI tract, prove that it can be measured in plasma as valuable diagnostic marker of disease in the form of complexes with IgG that also exert immune-modulating activities on circulating immune cells.

  12. High GRP94 expression is associated with endometrioid adenocarcinoma.

  13. Immuno-stimulating peptide derived from HMGB1 is more effective than the N-terminal domain of Gp96 as an endogenous adjuvant for improvement of protein vaccines.

  14. These data demonstrate the essential role of the gp96-TLR interaction in priming T cell immunity and provide further molecular basis for the coupling of gp96-mediated innate with adaptive immunity.

  15. mutations in GRP94 that affect its IGF chaperone activity represent a novel causal genetic mechanism that limits IGF biosynthesis, quite a distinct mechanism from the known genes in the GH/IGF signaling network.

  16. In this instance, the ATP5B/CALR/HSP90B1/HSPB1/HSPD1-signaling network was revealed as the predominant target which was associated with the majority of the observed protein-protein interactions. As a result, the identified targets may be useful in explaining the anticancer mechanisms of ursolic acid and as potential targets for colorectal cancer therapy.

  17. High HSP90B1 expression is associated with non-small-cell lung cancer.

  18. data suggest that the GRP94/CCT8/c-Jun/EMT signaling cascade might be a new therapeutic target for HCC

  19. We filtered four OSCC genes including SERPINB9, SERPINE2, GAK, and HSP90B1 through the gene global prioritization score (P < 0.005).

  20. Our results demonstrated that GRP94 is a key molecule in Hepatocellular carcinoma (HCC) progression that modulates the AKT pathway and eNOS levels

Mouse (Murine) Tektin 4 (TEKT4) Interaktionspartner

  1. Data suggest that Tektin 4 is not associated with axonemal tubulins but instead associated with Outer Dense Fibers in rodent spermatozoa.

  2. TEKT4 is necessary for the proper coordinated beating of the sperm flagellum and male reproductive physiology

Cow (Bovine) Tektin 4 (TEKT4) Interaktionspartner

  1. This study demonstrates that the expression patterns of tektin-4 were a proxy for an effect on spermatozoa motility and consequently bull infertility.

Tektin 4 (TEKT4) Protein Überblick

Protein Überblick

This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15.

Genbezeichner und Symbole assoziert mit Tektin 4 Proteine (TEKT4)

  • heat shock protein 90 beta family member 1 (HSP90B1)
  • tektin 4 (Tekt4)
  • tektin 4 (TEKT4)
  • tektin-4 (LOC490081)
  • tektin 4 S homeolog (tekt4.S)
  • tektin 4 (tekt4)
  • tektin-4 (LOC100719827)
  • tektin-4 (LOC110259951)
  • 1700010L19Rik Protein
  • ECGP Protein
  • GP96 Protein
  • GRP94 Protein
  • RGD1308075 Protein
  • Tek4 Protein
  • Tekt4 Protein
  • Tektin4 Protein
  • TRA1 Protein

Bezeichner auf Proteinebene für Tektin 4 Proteine (TEKT4)

94 kDa glucose-regulated protein , endoplasmin , endothelial cell (HBMEC) glycoprotein , heat shock protein 90 kDa beta member 1 , stress-inducible tumor rejection antigen gp96 , tumor rejection antigen (gp96) 1 , tumor rejection antigen 1 , tektin-4 , testicular microtubules-related protein 4 , tektin 4

7184 Homo sapiens
71840 Mus musculus
150483 Homo sapiens
302991 Rattus norvegicus
416527 Gallus gallus
459397 Pan troglodytes
490081 Canis lupus familiaris
496070 Xenopus laevis
510343 Bos taurus
559407 Danio rerio
708925 Macaca mulatta
100145069 Xenopus (Silurana) tropicalis
100598078 Nomascus leucogenys
100719827 Cavia porcellus
110259951 Sus scrofa
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